User profiles for Neelam Malik

Dr. Neelam Malik

Associate professor, department of pharmacy, PIET
Verified email at piet.co.in
Cited by 387

Quercetin and related chromenone derivatives as monoamine oxidase inhibitors: targeting neurological and mental disorders

P Dhiman, N Malik, E Sobarzo-Sánchez, E Uriarte… - Molecules, 2019 - mdpi.com
Monoamine oxidase inhibitions are considered as important targets for the treatment of
depression, anxiety, and neurodegenerative disorders, including Alzheimer’s and Parkinson’s …

Mechanistic approach towards interaction of newly synthesized Hesperidin derivatives against xanthine oxidase

N Malik, P Dhiman, A Khatkar - International journal of biological …, 2019 - Elsevier
Xanthine oxidase is an important enzyme of purine catabolism pathway and has been
associated directly in pathogenesis of gout and indirectly in many pathological conditions like …

Lead optimization for promising monoamine oxidase inhibitor from eugenol for the treatment of neurological disorder: Synthesis and in silico based study

P Dhiman, N Malik, A Khatkar - BMC chemistry, 2019 - Springer
Natural based inhibitors of monoamine oxidase are promising drug candidates for the treatment
of several neurodegenerative and neuropsychological disorders including depression, …

Leiomyoma of bladder

PJ Sudhakar, N Malik, A Malik - Saudi Journal of Kidney Diseases …, 2008 - journals.lww.com
A case of leiomyoma of urinary bladder, a rare benign tumor, is presented. The patient was
a 45-year-old woman with long duration history of dysuria. Intravenous urography (IVU), …

3D-QSAR and in-silico studies of natural products and related derivatives as monoamine oxidase inhibitors

P Dhiman, N Malik, A Khatkar - Current neuropharmacology, 2018 - ingentaconnect.com
Background: The computational development of human monoamine oxidase (MAO)
inhibitors led to advancement in drug design and the treatment of many neurodegenerative …

In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

N Malik, P Dhiman, A Khatkar - BMC chemistry, 2019 - Springer
Background Xanthine oxidase is an important enzyme of purine catabolism pathway and
has been associated directly in pathogenesis of gout and indirectly in many pathological …

Molecular docking, synthesis, α-amylase inhibition, urease inhibition and antioxidant evaluation of 4-hydroxy-3-methoxy benzoic acid derivatives

A Malik, N Malik, P Dhiman, A Khatkar… - Research Journal of …, 2019 - indianjournals.com
Different derivatives of 4-hydroxy-3-methoxy benzoic acid were synthesized and evaluated
for their antioxidant, α-amylase inhibition and urease inhibition ability. Antioxidant evaluation …

Flavonoids and anthranquinones as xanthine oxidase and monoamine oxidase inhibitors: a new approach towards inflammation and oxidative stress

N Malik, P Dhiman… - Current Topics in …, 2018 - ingentaconnect.com
The development of xanthine oxidase and monoamine oxidase inhibitors led to important
breakthroughs in the therapy of oxidative damage, hyperuricemia, gout, neurological, …

Natural based piperine derivatives as potent monoamine oxidase inhibitors: an in silico ADMET analysis and molecular docking studies

P Dhiman, N Malik, A Khatkar - BMC chemistry, 2020 - Springer
Neurodegenerative disorders follow numerous pathological ways concerning overexpression
of monoamine oxidase and formation of reactive oxygen species. The computational …

Hybrid caffeic acid derivatives as monoamine oxidases inhibitors: synthesis, radical scavenging activity, molecular docking studies and in silico ADMET analysis

P Dhiman, N Malik, A Khatkar - Chemistry Central Journal, 2018 - Springer
Background Monoamine oxidase has been implicated in numerous neurological disorders.
Although synthetic monoamine oxidase inhibitors (MAOI) have emerged with many side …