User profiles for Olabode P. Oluwole

Professor Olabode Peter Oluwole

College of Health Sciences, University of Abuja
Verified email at uniabuja.edu.ng
Cited by 356

Evidence of novel susceptibility variants for prostate cancer and a multiancestry polygenic risk score associated with aggressive disease in men of African ancestry

…, HO Ajibola, MA Jamda, OP Oluwole… - European urology, 2023 - Elsevier
Background Genetic factors play an important role in prostate cancer (PCa) susceptibility.
Objective To discover common genetic variants contributing to the risk of PCa in men of African …

[HTML][HTML] Testing the generalizability of ancestry-specific polygenic risk scores to predict prostate cancer in sub-Saharan Africa

…, MM Nwegbu, HO Ajibola, OP Oluwole… - Genome biology, 2022 - Springer
Background Genome-wide association studies do not always replicate well across populations,
limiting the generalizability of polygenic risk scores (PRS). Despite higher incidence and …

Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations

…, HO Ajibola, MA Jamda, OP Oluwole… - Elife, 2022 - elifesciences.org
Background: We recently developed a multi-ancestry polygenic risk score (PRS) that
effectively stratifies prostate cancer risk across populations. In this study, we validated the …

Whole-exome sequencing of Nigerian prostate tumors from the prostate cancer transatlantic consortium (CaPTC) reveals DNA repair genes associated with african …

…, A Popoola, OA Fatiregun, OP Oluwole… - Cancer Research …, 2022 - AACR
In this study, we used whole-exome sequencing of a cohort of 45 advanced-stage, treatment-naïve
Nigerian (NG) primary prostate cancer tumors and 11 unmatched nontumor tissues to …

Whole‐exome sequencing of Nigerian benign prostatic hyperplasia reveals increased alterations in apoptotic pathways

…, A Popoola, OA Fatiregun, OP Oluwole… - The …, 2024 - Wiley Online Library
Background Through whole‐exome sequencing of 60 formalin‐fixed paraffin‐embedded
Nigerian (NGRn) benign prostatic hyperplasia (BPH) samples, we identified germline and …

[PDF][PDF] Utility of formalin-fixed, paraffin-embedded prostate biospecimens from low-resource settings for use in next-generation sequencing studies in African-descent …

…, AA Popoola, OA Fatiregun, OP Oluwole… - Journal of Global Health …, 2023 - joghr.org
# Background Men of African ancestry experience higher burden from prostate cancer
compared to men of other ancestral backgrounds. Limitations in the availability of high-quality …

[HTML][HTML] Gossypiboma: a cause of iatrogenic fecal entero-cutaneous fistula

OP Oluwole, AMF Akinnagbe, EJC Nwana… - Journal of Medicine in …, 2015 - journals.lww.com
Gossypiboma or textiloma is used to describe a retained surgical swab in the body after an
operation. Inadvertent retention of a foreign body in the abdomen often requires another …

Tumor only analysis of whole exome sequencing from a multi-institutional Nigerian prostate cancer cohort reveals DNA repair genes associated with African ancestry

…, S Rotimi, A Popoola, OA Fatiregun, OP Oluwole… - Cancer Research, 2022 - AACR
Men of African ancestry (MAA) have the highest global incidence and mortality of prostate
cancer (PCa); however, the biology underlying this harsh disease presentation remains poorly …

Development, evaluation, and implementation of a pan-African cancer research network: men of African descent and carcinoma of the prostate

…, AM Jamda, PO Olabode… - Journal of global …, 2018 - ascopubs.org
Purpose Cancer of the prostate (CaP) is the leading cancer among men in sub-Saharan
Africa (SSA). A substantial proportion of these men with CaP are diagnosed at late (usually …

[PDF][PDF] Superficial skin ulcers

…, AH Rafindadi, SA Adewuyi, OP Oluwole - Saudi medical …, 2007 - researchgate.net
Methods. A total of 670 patients with superficial skin ulcers were retrospectively analyzed
over a 15-year period (January 1991 to December 2005). Tissue biopsies of these patients …