Cleft lip and palate

PA Mossey, J Little, RG Munger, MJ Dixon, WC Shaw - The Lancet, 2009 - thelancet.com
Clefts of the lip and palate are generally divided into two groups, isolated cleft palate and
cleft lip with or without cleft palate, representing a heterogeneous group of disorders affecting …

Size and shape measurement in contemporary cephalometrics

GT McIntyre, PA Mossey - The European Journal of …, 2003 - academic.oup.com
The traditional method of analysing cephalograms—conventional cephalometric analysis (CCA)—involves
the calculation of linear distance measurements, angular measurements, …

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24

…, B Horsthemke, FJ Kramer, TF Wienker, PA Mossey… - Nature …, 2009 - nature.com
We conducted a genome-wide association study involving 224 cases and 383 controls of
Central European origin to identify susceptibility loci for nonsyndromic cleft lip with or without …

[PDF][PDF] Global registry and database on craniofacial anomalies: Report of a WHO Registry Meeting on Craniofacial Anomalies

PA Mossey, EE Catilla - 2003 - apps.who.int
Acknowledgemen wledgemen wledgements: This meeting was organized by the World Health
Organization, with financial support from the National Insititute of Dental and Craniofacial …

Global economic impact of dental diseases

S Listl, J Galloway, PA Mossey… - Journal of dental …, 2015 - journals.sagepub.com
Reporting the economic burden of oral diseases is important to evaluate the societal
relevance of preventing and addressing oral diseases. In addition to treatment costs, there are …

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

…, TF Wienker, M Knapp, M Rubini, PA Mossey… - Nature …, 2010 - nature.com
We conducted a genome-wide association study for nonsyndromic cleft lip with or without
cleft palate (NSCL/P) in 401 affected individuals and 1,323 controls, with replication in an …

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

…, PA Mossey… - Nature …, 2008 - nature.com
Previously we have shown that nonsyndromic cleft lip with or without cleft palate (NSCL/P) 1
is strongly associated with SNPs in IRF6 (interferon regulatory factor 6) 2 . Here, we use …

[PDF][PDF] Hypodontia—a retrospective review of prevalence and etiology. Part I

CJ Larmour, PA Mossey, BS Thind, AH Forgie… - Quintessence …, 2005 - academia.edu
A retrospective literature review was carried out to determine the prevalence of hypodontia
and current knowledge of associated etiological factors. Reported studies vary widely in their …

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

…, RP Steegers-Theunissen, M Rubini, PA Mossey… - Nature …, 2012 - nature.com
We have conducted the first meta-analyses for nonsyndromic cleft lip with or without cleft
palate (NSCL/P) using data from the two largest genome-wide association studies published to …

A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24. 2, 17q23 and 19q13

…, CJ Buxó, A Butali, PA Mossey… - Human molecular …, 2016 - academic.oup.com
Orofacial clefts (OFCs), which include non-syndromic cleft lip with or without cleft palate (CL/P),
are among the most common birth defects in humans, affecting approximately 1 in 700 …