Zwitterionic nanocarriers have emerged as a new class of biocompatible nanomaterials
with outstanding stealth capability in blood circulation. In this work, a novel biodegradable …

Nanoparticles (NPs) are promising carriers for dermal and transdermal drug delivery. However,
the underlying dynamics of drug release from the NPs, especially, how the physiological …

The unique structure and protective mechanisms of the eye result in low bioavailability of
ocular drugs. Using a mucoadhesive material is an efficient solution to improve ocular drug …

The dissolving microneedle array (DMNA) offers a novel potential approach for transdermal
delivery of biological macromolecular drugs and vaccines, because it can be as efficient as …

Paclitaxel is a widely used chemotherapy drug for advanced laryngeal cancer patients.
However, the fact that there are 20-40% of advanced laryngeal cancer patients do not response …

Background Pathological levels of blood lipids could be one of the causes of sudden
sensorineural hearing loss (SSNHL). The objective of this manuscript is therefore to evaluate the …

Objectives: To investigate whether hypoxia has an effect on regulation of multidrug resistance
(MDR) to chemotherapeutic drugs in laryngeal carcinoma cells and explore the role of …

Objectives Previous reports suggest a strong association between human papillomavirus (HPV)
and the etiology of laryngeal squamous cell carcinoma (LSCC). However, clinical data …

N4-acetylcytidine (ac4C) is a post-transcriptional RNA modification that regulates in various
important biological processes. However, its role in human cancer, especially lymph node …

Background Obstructive sleep apnea (OSA) is a common and severe social problem.
Erectile dysfunction (ED) is an important health concern. The prevalence of OSA with ED is …