Objectives: This project was designed to evaluate the effects of melatonin and zinc on the
glycemic control in type 2 diabetes mellitus (T2DM) patients with inadequate response to the …

The protective effect of ginger extract against cisplatin-induced hepatotoxicity and cardiotoxicity
was evaluated in 30 albino white rats(weighing 200-300 gm ) classified into 5groups (6 …

Background Ciliopathies are a group of diseases associated with abnormal structure or
function of primary cilia. Ciliopathies include polycystic kidney disease (PKD), a pathology …

Drug–induced nephrotoxicity is an important cause of renal failure. Aminoglycoside antibiotics,
such as amikacin, which causes ototoxicity and nephrtotoxicity as a main side effects, this …

Objective: This study evaluated the effect of melatonin on the response of patients suffering
from metabolic syndrome (MEBS) treated with metformin. Design: This study used two-armed …

Glycemic control and prevention of secondary complications are the most important goals of
using pharmacologic treatment of diabetes mellitus (DM). The inadequate responses to oral …

L-carnitine is a small compound found mostly in milk and meat. Supplementation with L-carnitine
in animals has been associated with improvement in some abnormalities. Carnitine …

Probiotics are defined as live microorganisms that, when administered in adequate amount,
confer a health benefit on the host. The aim of this study was to investigate the effects of …

The α-pyrone antibiotic myxopyronin (Myx) inhibits bacterial RNA polymerase (RNAP). Here,
through a combination of genetic, biochemical, and structural approaches, we show that …

We define the target, mechanism, and structural basis of inhibition of bacterial RNA polymerase
(RNAP) by the tetramic acid antibiotic streptolydigin (Stl). Stl binds to a site adjacent to …