In 30% of epileptic individuals, intractable epilepsy represents a problem for the management
of seizures and severely affects the patient's quality of life due to pharmacoresistance with …

… disease (CD) and ulcerative colitis (UC), results in substantial morbidity and is difficult to
treat. New strategies for adjunct therapies are needed. Systemic corticosteroids are highly …

Hepatocellular carcinoma accounts for about 80–90% of all liver cancer and is the fourth most
common cause of cancer mortality. Although there are many strategies for the treatment of …

This study has been initiated to investigate whether endogenous carnitine depletion and/or
carnitine deficiency is a risk factor during development of cisplatin (CDDP)-induced …

Diabetic retinopathy (DR) is one of the leading causes of decreased vision and blindness
worldwide. Diabetes-induced oxidative stress is believed to be the key factor that initiates …

… mechanism(s) is poorly understood. Our objective is to help in understanding such mechanism(s)
… Lipopolysaccaride (LPS) is used as a model of animal sepsis while L-carnitine (LCR) …

AIM: To investigate whether carnitine deficiency is a risk factor during the development of
diethylnitrosamine (DENA)-induced hepatic carcinogenesis. METHODS: A total of 60 male …

Diabetic retinopathy is widely recognized as a neurodegenerative disease of the eye.
Increased oxidative stress has been considered the central factor in damaging neural retina in …

Objectives: Present study aims to investigate the ameliorative effects of naringenin (NG) on
experimentally induced diabetic neuropathy (DN) in rats. Methods: Diabetes was induced by …

Diabetes-induced damages in brain are known as diabetic encephalopathy, which is well
characterized by cellular, molecular and functional changes in the brain of diabetic subjects …