Aims: Ischemia-reperfusion injury (IRI)-induced acute kidney injury (IRI-AKI) is characterized
by elevated levels of reactive oxygen species (ROS), mitochondrial dysfunction, and …

Hydraulic tomography (ie, a sequential aquifer test) has recently been proposed as a method
for characterizing aquifer heterogeneity. During a hydraulic tomography experiment, water …

Metagenome of gut microbes has been implicated in metabolism, immunity, and health
maintenance of its host. However, in most of previous studies, the microbiota was sampled from …

The ability of articular cartilage to repair itself is limited because it lacks blood vessels, nerves,
and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating the …

Cartilage extracellular matrix (ECM) is composed primarily of the network type II collagen (COLII)
and an interlocking mesh of fibrous proteins and proteoglycans (PGs), hyaluronic acid (…

Mitochondrial dysfunction is a key feature of injury to numerous tissues and stem cell aging.
Although the tissue regenerative role of mesenchymal stem cell (MSC)-derived extracellular …

Articular cartilage (AC) injury repair has always been a difficult problem for clinicians and
researchers. Recently, a promising therapy based on mesenchymal stem cells (MSCs) has …

Articular cartilage is susceptible to damage but hard to self-repair due to its avascular nature.
Traditional treatment methods are not able to produce satisfactory effects. Mesenchymal …

In mammals, the microbiota can be transmitted from the placenta, uterus, and vagina of the
mother to the infant. Unlike mammals, development of the avian embryo is a process isolated …

Macrophages (Mφ) are primary innate immune cells that exhibit diverse functions in response
to different pathogens or stimuli, and they are extensively involved in the pathology of …