7.3 A 189× 600 back-illuminated stacked SPAD direct time-of-flight depth sensor for automotive LiDAR systems

…, Y Otake, T Wakano, T Izawa - … Solid-State Circuits …, 2021 - ieeexplore.ieee.org
There have been many developments in Light Detection And Ranging (LiDAR) sensors used
in Autonomous Driving (AD) and Advanced Driver Assistance Systems (ADAS) to measure …

4.9 A 1ms high-speed vision chip with 3D-stacked 140GOPS column-parallel PEs for spatio-temporal image processing

…, L Miyashita, Y Watanabe, T Izawa… - … Solid-State Circuits …, 2017 - ieeexplore.ieee.org
High-speed vision systems that combine high-frame-rate imaging and highly parallel signal
processing enable instantaneous visual feedback to rapidly control machines over human-…

Talin1 and Rap1 are critical for osteoclast function

W Zou, T Izawa, T Zhu, J Chappel, K Otero… - … and cellular biology, 2013 - Am Soc Microbiol
To determine talin1's role in osteoclasts, we mated TLN1 fl/fl mice with those expressing
cathepsin K-Cre (CtsK-TLN1) to delete the gene in mature osteoclasts or with lysozyme M-Cre (…

9.6 A 1/2.3 inch 12.3 Mpixel with on-chip 4.97 TOPS/W CNN processor back-illuminated stacked CMOS image sensor

…, Y Livne, G Yuval, E Zyss, T Izawa - … Solid-State Circuits …, 2021 - ieeexplore.ieee.org
Within the Internet of Things (IoT) market, retail, smart city, and so on, the need for camera
products which have Artificial Intelligence (AI) processing capabilities is growing. AI …

c-Src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton

T Izawa, W Zou, JC Chappel, JW Ashley… - … and cellular biology, 2012 - Am Soc Microbiol
RANK ligand (RANKL), by mechanisms unknown, directly activates osteoclasts to resorb bone.
Because c-Src is key to organizing the cell's cytoskeleton, we asked if the tyrosine kinase …

[HTML][HTML] The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-Fos signaling axis

T Izawa, R Arakaki, H Mori, T Tsunematsu… - The Journal of …, 2016 - journals.aai.org
The aryl hydrocarbon receptor (AhR) pathway plays a key role in receptor activator of NF-κB
ligand (RANKL)–mediated osteoclastogenesis. However, the mechanism underlying the …

[PDF][PDF] ASXL2 regulates glucose, lipid, and skeletal homeostasis

T Izawa, N Rohatgi, T Fukunaga, QT Wang, MJ Silva… - Cell reports, 2015 - cell.com
ASXL2 is an ETP family protein that interacts with PPARγ. We find that ASXL2−/− mice are
insulin resistant, lipodystrophic, and fail to respond to a high-fat diet. Consistent with genetic …

[HTML][HTML] Macrophage motility in wound healing is regulated by HIF-1α via S1P signaling

IR Hutami, T Izawa, T Khurel-Ochir, T Sakamaki… - International journal of …, 2021 - mdpi.com
Accumulating evidence indicates that the molecular pathways mediating wound healing
induce cell migration and localization of cytokines to sites of injury. Macrophages are immune …

Estrogen deficiency accelerates murine autoimmune arthritis associated with receptor activator of nuclear factor-κB ligand-mediated osteoclastogenesis

…, N Ishimaru, R Arakaki, M Kobayashi, T Izawa… - …, 2004 - academic.oup.com
The aims of this study were to evaluate the in vivo effects of estrogen deficiency in MRL/lpr
mice as a model for rheumatoid arthritis and to analyze the possible relationship between …

[HTML][HTML] Effectiveness of presurgical nasoalveolar molding therapy on unilateral cleft lip nasal deformity

…, Y Kuroda, N Kawai, K Watanabe, T Izawa… - Saudi medical …, 2018 - ncbi.nlm.nih.gov
Objectives: To evaluate the effectiveness of pre-surgical nasoalveolar molding (PNAM) in
patients with unilateral cleft lip nasal deformities. Methods: This was a retrospective study …