Previously, we found that nodule formation, a cellular defense response in insects, is regulated
by humoral factors called C-type lectins in the hemolymph. To elucidate the factors that …

Although microtubule inhibitors (MTI) remain a therapeutically valuable payload option for
antibody drug conjugates (ADCs), some cancers do not respond to MTI-based ADCs. Efforts …

Pyrrolobenzodiazepine (PBD) dimers are well-known highly potent antibody drug conjugate
(ADC) payloads. The corresponding PBD monomers, in contrast, have received much less …

Tourism has become the most rapidly growing industry worldwide and ecotourism is
considered as the fastest growing tourism segment. Ecotourism is a method to conserve the …

Bone cancer pain (BCP) is a common chronic pain that is caused by a primary or metastatic
bone tumor. More detailed molecular mechanisms of BCP are warranted. In this study, we …

Nodule formation is a two-step cell-mediated immune response that is elicited by the
cytokine spätzle1. Spätzle1 is activated within 30 s of invasion by microorganisms via an …

An analysis and statistical evaluation of the environmental air quality, meteorological conditions,
and human health effects were carried out for major cities and towns in Tibet. The study …

Although China has a profound history of health culture, the development of health tourism
started late. At present, there are few kinds of eco-health tourism products, and the quality is …

This article considers the pricing strategies of a manufacturer in a two-echelon supply chain
with service leveldependent demand. This chain consists of one manufacturer and two …

The existence of an extracellular signaling pathway that mediates nodule formation, a cell‐mediated
immune response, has been reported in Bombyx mori larvae. In this pathway, C‐…