[HTML][HTML] Hydrazinocurcumin Encapsuled nanoparticles “re-educate” tumor-associated macrophages and exhibit anti-tumor effects on breast cancer following STAT3 …
…, X Wang, W Dang, H Tang, H Cao, L Wang, T Chen - PloS one, 2013 - journals.plos.org
Tumor-associated macrophages (TAMs) are essential cellular components within tumor
microenvironment (TME). TAMs are educated by TME to transform to M2 polarized population, …
microenvironment (TME). TAMs are educated by TME to transform to M2 polarized population, …
[HTML][HTML] Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T …
…, H Qian, Q Zeng, Y Wang, F Jin, C Chai, T Chen - Journal of Experimental …, 2021 - Springer
Background Progranulin (PGRN), as a multifunctional growth factor, is overexpressed in
multiple tumors, but the role of PGRN on tumor immunity is still unclear. Here, we studied the …
multiple tumors, but the role of PGRN on tumor immunity is still unclear. Here, we studied the …
Activation of IL-8 via PI3K/Akt-dependent pathway is involved in leptin-mediated epithelial-mesenchymal transition in human breast cancer cells
…, H Tang, Y Huang, L Wei, M Su, T Chen - Cancer biology & …, 2015 - Taylor & Francis
… Lin Wang, Cuiping Tang and Tingmei Chen concepted and designed the research, wrote the
… Yunxiu Huang providied reagents; Lan Wei, Min Su and Tingmei Chen analyzed the data. …
… Yunxiu Huang providied reagents; Lan Wei, Min Su and Tingmei Chen analyzed the data. …
[HTML][HTML] Leptin promotes breast cancer cell migration and invasion via IL-18 expression and secretion
…, N Wang, F Ji, C Zhong, T Chen - International …, 2016 - spandidos-publications.com
In recent years, crosstalk between tumor microenvironment and cancer cells have received
increasing attention. Accumulating research data suggests that leptin, a key adipokine …
increasing attention. Accumulating research data suggests that leptin, a key adipokine …
Reduced mother-to-child transmission of hepatitis B after implementation of completely charge-free active-passive immunoprophylaxis: an observational cohort study
B Xu, C Xu, J Feng, J Chen, Y Rui, Z Qiu… - Expert Review of …, 2021 - Taylor & Francis
Objectives: China has implemented universal hepatitis B vaccination since 2002 and provided
charge-free hepatitis B immunoglobulin (HBIG) to infants of HBV-infected mothers since …
charge-free hepatitis B immunoglobulin (HBIG) to infants of HBV-infected mothers since …
The miR-186-3p/EREG axis orchestrates tamoxifen resistance and aerobic glycolysis in breast cancer cells
M He, Q Jin, C Chen, Y Liu, X Ye, Y Jiang, F Ji, H Qian… - Oncogene, 2019 - nature.com
Tamoxifen resistance is one of the major challenges for its medical uses in estrogen receptor
(ER)-positive breast cancer. Aerobic glycolysis, an anomalous characteristic of glucose …
(ER)-positive breast cancer. Aerobic glycolysis, an anomalous characteristic of glucose …
[HTML][HTML] Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2
…, J Yang, Z Zhang, Y Jiang, Y Liu, T Chen - Journal of Experimental …, 2016 - Springer
Background Accumulating researches have shown that epithelial-mesenchymal transition (EMT)
contributes to tumor metastasis. Leptin, a key adipokine secreted from adipocytes, …
contributes to tumor metastasis. Leptin, a key adipokine secreted from adipocytes, …
The role of proto-oncogene Fra-1 in remodeling the tumor microenvironment in support of breast tumor cell invasion and progression
…, C Kaplan, D Liao, D Markowitz, C Liu, T Chen… - Oncogene, 2010 - nature.com
A growing body of evidence indicates that interactions between neoplastic cells and tumor-associated
macrophages (TAMs) in the tumor microenvironment (TME) are crucial in …
macrophages (TAMs) in the tumor microenvironment (TME) are crucial in …
Fiber optic surface plasmon resonance biosensor for detection of PDGF-BB in serum based on self-assembled aptamer and antifouling peptide monolayer
…, X Wei, Y Fan, D Gan, S Yue, W Cheng, T Chen - Biosensors and …, 2019 - Elsevier
Herein, a home-build fiber optic surface plasmon resonance (FO-SPR) biosensing platform
has been developed for highly sensitive detection of platelet-derived growth factor (PDGF-BB…
has been developed for highly sensitive detection of platelet-derived growth factor (PDGF-BB…
Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2
…, Y Jiang, Y Liu, Z Zhang, J Yang, L Wei, T Chen… - Cellular Oncology, 2017 - Springer
Background Previously, it has been shown that obesity may be considered as a risk factor
for breast cancer in postmenopausal women. Leptin, a hormone whose level is elevated in …
for breast cancer in postmenopausal women. Leptin, a hormone whose level is elevated in …