[HTML][HTML] Activation of stimulation of interferon genes (STING) signal and cancer immunotherapy

K Luo, N Li, W Ye, H Gao, X Luo, B Cheng - Molecules, 2022 - mdpi.com
Stimulator of interferon gene (STING), an intracellular receptor in the endoplasmic reticulum,
could induce the production of cytokines such as type I interferon (IFN) by activating the …

Iron overload-induced osteocyte apoptosis stimulates osteoclast differentiation through increasing osteocytic RANKL production in vitro

J Yang, D Dong, X Luo, J Zhou, P Shang… - Calcified Tissue …, 2020 - Springer
Iron overload is closely associated with osteoporosis, the potential cellular mechanism involved
in decreased osteoblast differentiation and increased osteoclast formation. However, the …

Piperlongumine inhibits the progression of osteosarcoma by downregulating the SOCS3/JAK2/STAT3 pathway via miR-30d-5p

Y Hu, X Luo, J Zhou, S Chen, M Gong, Y Deng… - Life sciences, 2021 - Elsevier
Aims The present study evaluated the functions of Piperlongumine (PL) in osteosarcoma (OS)
cell growth and metastasis both in vitro and in vivo. Main methods MTT assay was …

[HTML][HTML] Epothilone B facilitates peripheral nerve regeneration by promoting autophagy and migration in schwann cells

…, Y Hu, S Chen, X Luo, H Zhang, Z Luo… - Frontiers in Cellular …, 2020 - frontiersin.org
The search for drugs that can facilitate axonal regeneration and elongation following peripheral
nerve injury has been an area of increasing interest in recent years. Epothilone B (EpoB) …

Tea polyphenol EGCG inhibited colorectal-cancer-cell proliferation and migration via downregulation of STAT3

KW Luo, J Xia, BH Cheng, HC Gao… - Gastroenterology …, 2021 - academic.oup.com
Background Green tea is a popular beverage worldwide and epigallocatechin-3-gallate (EGCG)
is the most bioactive polyphenol in green tea. Our study aims to investigate the anti-…

[HTML][HTML] EGCG inhibited bladder cancer T24 and 5637 cell proliferation and migration via PI3K/AKT pathway

KW Luo, WY Lung, XL Luo, WR Huang - Oncotarget, 2018 - ncbi.nlm.nih.gov
Epigallocatechin-3-gallate (EGCG), the bioactive polyphenol in green tea, has been demonstrated
to have various biological activities. We previously found that EGCG inhibited SW780 …

[HTML][HTML] EGCG enhanced the anti-tumor effect of doxorubicine in bladder cancer via NF-κB/MDM2/p53 pathway

KW Luo, X Zhu, T Zhao, J Zhong, H Gao… - Frontiers in Cell and …, 2020 - frontiersin.org
Doxorubicin (DOX), the first-line chemotherapy for bladder cancer, usually induces side
effects. We previously demonstrated that green tea polyphenol EGCG had potent anti-tumor …

Effects of salmon calcitonin on fracture healing in ovariectomized rats.

X Li, X Luo, N Yu, B Zeng - Saudi medical journal, 2007 - europepmc.org
Objective To explore the effects of salmon calcitonin on the healing process of osteoporotic
fractures in ovariectomized rats. Methods We performed this study in The First Affiliated …

Methoxytetrahydro‐2H‐pyran‐2‐yl) methyl benzoate inhibits spinal cord injury in the rat model via PPAR‐γ/PI3K/p‐Akt activation

H Zhang, M Gong, X Luo - Environmental toxicology, 2020 - Wiley Online Library
Spinal cord injury (SCI) is the most commonly seen trauma leading to disability in people
worldwide. The purpose of current study was to determine the protective effect of …

[HTML][HTML] Identification and validation of a potent multi-mirna signature for prediction of prognosis of osteosarcoma patients

X Luo, J Tang, H Xuan, J Liu, X Li - Medical Science Monitor …, 2020 - ncbi.nlm.nih.gov
Xinle Luo, A, B Jiuyang Tang, corresponding author A, B, F Huabing Xuan, B, E Jianlin
Liu, B, E, F and Xi Li A, E … Luo et al. revealed that miR-212 was significantly …