Introduction: Opioid-induced constipation (OIC) is a common adverse effect in patients under
long-term opioid therapy. Naldemedine is a novel peripherally acting μ-opioid receptor …

MicroRNAs (miRNAs) are small non-coding RNAs that play critical roles in cervical
carcinogenesis and progression. microRNA-133a (miR-133a) has been reported to play a tumor-…

Background: Gastric cancer is one of the most important malignancies with poor prognosis.
Ferroptosis and cuproptosis are newly discovered metal-dependent types of programmed …

Purpose: Ketamine is widely used in pediatric anesthesia. Recent studies have demonstrated
that excessive application of ketamine leads to cortical neurodegeneration in neonatal …

Background Radial artery cannulation in young children is challenging. A single-operator
laser-assisted ultrasound-guidance system was invented to project the path of the target artery …

Electrocatalysis plays a vital role in energy conversion and storage in modern society.
Localized surface plasmon resonance (LSPR) is a highly attractive approach to enhance the …

Kisspeptin (Kiss) plays a critical role in mediating gonadal steroid feedback to the
gonadotropin-releasing hormone (GnRH) neurons in mammals. However, little information regarding …

The electrochemical (EC) reduction of CO2 is a promising approach for value-added fuel or
chemical production. Cu-based electrodes have been extensively used as a ‘star’ material …

Leptin (Lep) is a key factor for the regulation of food intake and energy homeostasis in
mammals. To date, a number of studies have provided evidence for the existence of multiple …

There has been growing concern in recent years about contamination of foods by engineered
nanoparticles (NPs) due to their increasing applications in food packaging materials, …