Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells

…, J Huang, L Zhang, L Hu, L He, F Li, Y Xiao… - Biological and …, 2008 - jstage.jst.go.jp
Biol. Pharm. Bull. 31(4) 592-597 (2008) Page 1 Triptolide (Fig. 1), a highly oxygenated
diterpene separated from Tripterygium wilfordii HOOK. f (TWHf), is one of the main active …

BUB1 is identified as a potential therapeutic target for pancreatic cancer treatment

M Li, X Duan, Y Xiao, M Yuan, Z Zhao, X Cui… - Frontiers in Public …, 2022 - frontiersin.org
Pancreatic cancer is one of the most challenging cancer types in clinical treatment worldwide.
This study aimed to understand the tumorigenesis mechanism and explore potential …

Genomic correlates of programmed cell death ligand 1 (PD-L1) expression in Chinese lung adenocarcinoma patients

K Li, J Liu, L Wu, Y Xiao, J Li, H Du, Z Zhao… - Cancer Cell …, 2022 - Springer
Background Although PD-L1 expression is a crucial predictive biomarker for immunotherapy,
it can be influenced by many factors. Methods A total of 248 Chinese patients with lung …

Investigations of sequencing data and sample type on HLA class Ia typing with different computational tools

J Yi, L Chen, Y Xiao, Z Zhao, X Su - Briefings in Bioinformatics, 2021 - academic.oup.com
Human leukocyte antigen (HLA) can encode the human major histocompatibility complex (MHC)
proteins and play a key role in adaptive and innate immunity. Emerging clinical …

Identification of Clonal Neoantigens Derived From Driver Mutations in an EGFR-Mutated Lung Cancer Patient Benefitting From Anti-PD-1

…, Y Liu, J Wu, C Tian, Y Zeng, Z Zhao, Y Xiao… - Frontiers in …, 2020 - frontiersin.org
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have been
recommended as the first-line therapy for non-small cell lung cancer (NSCLC) patients harboring …

Will the use of solid fuels reduce the life satisfaction of rural residents—Evidence from China

L Zhang, Y Xiao, Q Wu, J Li - Energy for Sustainable Development, 2022 - Elsevier
Solid fuels usage may have a negative impact on people's living environment, worsen indoor
air quality, thus affect people's health status. Using CFPS panel data from 2010 to 2018, …

[HTML][HTML] The potential bioactive components of nine TCM prescriptions against COVID-19 in lung cancer were explored based on network pharmacology and …

L Du, Y Xiao, Y Xu, F Chen, X Chu, Y Cao… - Frontiers in …, 2022 - frontiersin.org
Objective: The purpose of this study was to screen active components and molecular targets
of nine prescriptions recommended by National Health Commission (NHC) of China by …

Transcription factor NFIC functions as a tumor suppressor in lung squamous cell carcinoma progression by modulating lncRNA CASC2

H Zhang, Z Luo, JM Tang, J Tian, Y Xiao, C Sun… - Cell Cycle, 2022 - Taylor & Francis
Nuclear factor I (NFI) family is emerging found playing oncogenic or tumor-suppressive
potential in cancers. However, the function and underlying mechanisms of NFIC, in the …

Complete response to first-line osimertinib monotherapy in a complex epidermal growth factor receptor mutant (L833V/H835L) lung adenocarcinoma patient: a case …

Z Luo, C Luo, R Zhou, Y Xiao, T Wang - Anti-Cancer Drugs, 2023 - journals.lww.com
Although uncommon epidermal growth factor receptor (EGFR) mutations account for 10–15%
EGFR mutant non-small cell lung cancer (NSCLC) patients, clinical evidence for …

[HTML][HTML] Identification of APC mutation as a potential predictor for immunotherapy in colorectal cancer

…, Z Zhao, C Sun, Y Zhao, H Lin, J Yang, Y Xiao… - Journal of …, 2022 - hindawi.com
To date, anticancer immunotherapy has presented some clinical benefits to most of advanced
mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) colorectal cancer (…