[HTML][HTML] Efficacy and safety of sintilimab plus pemetrexed and platinum as first-line treatment for locally advanced or metastatic nonsquamous NSCLC: a randomized …
Y Yang, Z Wang, J Fang, Q Yu, B Han, S Cang… - Journal of Thoracic …, 2020 - Elsevier
Introduction Sintilimab, an anti–programmed death 1 antibody, plus pemetrexed and
platinum had revealed promising efficacy for nonsquamous NSCLC in a phase 1b study. We …
platinum had revealed promising efficacy for nonsquamous NSCLC in a phase 1b study. We …
Measuring daily accessed street greenery: A human-scale approach for informing better urban planning practices
The public benefits of visible street greenery have been well recognised in a growing
literature. Nevertheless, this issue was rare to be included into urban greenery and planning …
literature. Nevertheless, this issue was rare to be included into urban greenery and planning …
The origin of negative stacking fault energies and nano-twin formation in face-centered cubic high entropy alloys
The secrets behind the exceptional mechanical properties of high entropy alloys (HEAs) at
cryogenic temperatures have drawn much attention in recent years. In this work, the negative …
cryogenic temperatures have drawn much attention in recent years. In this work, the negative …
[HTML][HTML] Resveratrol attenuates oxidative stress-induced intestinal barrier injury through PI3K/Akt-mediated Nrf2 signaling pathway
Y Zhuang, H Wu, X Wang, J He, S He… - Oxidative medicine and …, 2019 - hindawi.com
Oxidative stress is implicated in a wide range of intestinal disorders and closely associated
with their pathological processes. Resveratrol (RSV), a plant extract, plays a vital role in …
with their pathological processes. Resveratrol (RSV), a plant extract, plays a vital role in …
Conceptual design of the triple-column extractive distillation processes with single entrainer and double entrainer for separating the N-hexane/acetone/chloroform …
Currently, there are very limited efforts on investigating triple-column extractive distillation
process with single entrainer (S-TCED) for separating ternary multi-azeotropic mixture with …
process with single entrainer (S-TCED) for separating ternary multi-azeotropic mixture with …
Effect of first-line serplulimab vs placebo added to chemotherapy on survival in patients with extensive-stage small cell lung cancer: the ASTRUM-005 randomized …
…, Y Hotko, O Goloborodko, D Chen, M Wang, Z Yu… - Jama, 2022 - jamanetwork.com
Importance Programmed cell death ligand 1 inhibitors combined with chemotherapy has
changed the approach to first-line treatment in patients with extensive-stage small cell lung …
changed the approach to first-line treatment in patients with extensive-stage small cell lung …
Apatinib as second-line or later therapy in patients with advanced hepatocellular carcinoma (AHELP): a multicentre, double-blind, randomised, placebo-controlled …
…, W Fang, W Wu, G Wang, Y Cheng, Z Yu… - The lancet …, 2021 - thelancet.com
Background Inhibition of vascular endothelial growth factor receptor (VEGFR) has shown
antitumour activity in advanced hepatocellular carcinoma, but few studies of VEGFR inhibitors …
antitumour activity in advanced hepatocellular carcinoma, but few studies of VEGFR inhibitors …
Molecular targeted therapies elicit concurrent apoptotic and GSDME-dependent pyroptotic tumor cell death
Purpose: The induced death signals following oncogene inhibition underlie clinical efficacy
of molecular targeted therapies against human cancer, and defects of intact cell apoptosis …
of molecular targeted therapies against human cancer, and defects of intact cell apoptosis …
Effect of fruquintinib vs placebo on overall survival in patients with previously treated metastatic colorectal cancer: the FRESCO randomized clinical trial
…, D Ma, C Wu, Y Cheng, D Chen, W Li, S Sun, Z Yu… - Jama, 2018 - jamanetwork.com
Importance Patients with metastatic colorectal cancer (CRC) have limited effective and
tolerable treatment options. Objective To evaluate the efficacy and safety of oral fruquintinib, a …
tolerable treatment options. Objective To evaluate the efficacy and safety of oral fruquintinib, a …
[HTML][HTML] AENEAS: a randomized phase III trial of aumolertinib versus gefitinib as first-line therapy for locally advanced or metastaticnon–small-cell lung cancer with …
…, G Zhang, C Liu, J Li, X Yu, Z Lin, Z Yu… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
PURPOSE Aumolertinib (formerly almonertinib; HS-10296) is a novel third-generation
epidermal growth factor receptor tyrosine kinase inhibitor approved in China. This double-blind …
epidermal growth factor receptor tyrosine kinase inhibitor approved in China. This double-blind …