Macrophages and Polymorphonuclear neutrophils in lung defense and Injury1-2

Y Sibille, HY Reynolds - Am Rev Respir Dis, 1990 - atsjournals.org
Through the release of numerous secretory products (table 1) and the expression of several
surface receptors (table 2), the macrophage can interact with other cells and molecules. This …

Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease

P Bulpa, A Dive, Y Sibille - European Respiratory Journal, 2007 - Eur Respiratory Soc
Aspergillus spp. cultured in specimens from the airways of chronic obstructive pulmonary
disease (COPD) patients are frequently considered as a contaminant. However, growing …

Respiratory health and disease in Europe: the new European Lung White Book

…, B Lundbäck, Y Sibille - European Respiratory …, 2013 - Eur Respiratory Soc
The European Lung White Book–a major new overview of respiratory health in Europe
http://ow. ly/n7kRq http://ow. ly/n7kVX

Asthma phenotypes and IgE responses

…, SR Durham, P Chanez, Y Sibille… - European …, 2016 - Eur Respiratory Soc
The discovery of IgE represented a major breakthrough in allergy and asthma research,
whereas the clinical interest given to IgE in asthma has been blurred until the arrival of anti-IgE …

Lung mucosal immunity: immunoglobulin-A revisited

…, V Godding, JP Vaerman, Y Sibille - European …, 2001 - Eur Respiratory Soc
Mucosal defence mechanisms are critical in preventing colonization of the respiratory tract
by pathogens and penetration of antigens through the epithelial barrier. Recent research has …

Reduced epithelial expression of secretory component in small airways correlates with airflow obstruction in chronic obstructive pulmonary disease

…, JP Vaerman, M Decramer, Y Sibille - American journal of …, 2001 - atsjournals.org
The epithelial polymeric immunoglobulin receptor/transmembrane secretory component (pIgR/SC)
transports into secretions polymeric immunoglobulin A (pIgA), which is considered …

Clara cell protein in serum and bronchoalveolar lavage

…, S Depelchin, R Lauwerys, Y Sibille - European …, 1992 - Eur Respiratory Soc
The 10 kDa Clara cell protein was measured in serum and bronchoalveolar lavage (BAL)
from 39 healthy subjects (14 smokers, 25 nonsmokers) and from 41 patients with respiratory …

[HTML][HTML] LPS induces IL-10 production by human alveolar macrophages via MAPKinases-and Sp1-dependent mechanisms

H Chanteux, AC Guisset, C Pilette, Y Sibille - Respiratory research, 2007 - Springer
Background IL-10 is a cytokine mainly produced by macrophages that plays key roles in
tolerance to inhaled antigens and in lung homeostasis. Its regulation in alveolar macrophages (…

Protein content in bronchoalveolar lavage fluid of patients with asthma and control subjects

…, J Bousquet, P Godard, R Lauwerijs, Y Sibille… - Journal of allergy and …, 1995 - Elsevier
Background: Secretory component (SC), Clara cell protein (CC10) and to some extent, IgM
are proteins locally synthetized in airways. Albumin, α2-macroglobulin and α1-antitrypsin are …

Polymeric immunoglobulin receptor down-regulation in chronic obstructive pulmonary disease. Persistence in the cultured epithelium and role of transforming growth …

…, BA Weynand, GD Amatngalim, YM Sibille… - American journal of …, 2014 - atsjournals.org
Rationale: The generation of protective secretory IgA relies on the epithelial polymeric
immunoglobulin receptor (pIgR). pIgR expression is reduced in chronic obstructive pulmonary …