Background Over the last two decades, many epidemiological studies were performed to
describe risks and clinical presentations of melioidosis in endemic countries. Methods We …

Polymyxin B and colistin were examined for their ability to inhibit the type II NADH-quinone
oxidoreductases (NDH-2) of three species of Gram-negative bacteria. Polymyxin B and …

Early diagnosis is still as crucial as the initial stage of the COVID-19 pandemic. As RT-PCR
sometimes is not feasible in developing nations or rural areas, health professionals may use …

The dry antibiotic development pipeline coupled with the emergence of multidrug resistant
Gram-negative ‘superbugs’ has driven the revival of the polymyxin lipopeptide antibiotics. …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents
significant social, economic and political challenges worldwide. SARS-CoV-2 has caused …

Multidrug-resistant (MDR) Klebsiella pneumoniae may require combination therapy. We
systematically investigated bacterial killing with colistin and doripenem mono- and combination …

This study examines the interaction of polymyxin B and colistin with the surface and outer
membrane components of a susceptible and resistant strain of Klebsiella pneumoniae. The …

Background Respiratory symptoms including cough, runny nose, sore throat, and fever are
the most common clinical manifestations faced by hajj pilgrims in Mecca. The aim of the study …

Background Hajj pilgrimage faces numerous challenges including a high prevalence of
respiratory tract infection as well as its prevention strategies. The aim of this study was to …

Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
the causative agent of coronavirus disease 2019 (COVID-19) in late 2019, hundreds of …