[HTML][HTML] Long non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy

M Wang, D Han, Z Yuan, H Hu, Z Zhao, R Yang… - Cell death & …, 2018 - nature.com
Chemotherapy failure is the major cause of recurrence and poor prognosis in colorectal
cancer (CRC) patients. The role of the differentially expressed lncRNAs in 5-Fluorouracil …

Tumor-Triggered Controlled Drug Release from Electrospun Fibers Using Inorganic Caps for Inhibiting Cancer Relapse.

X Zhao, Z Yuan, L Yildirimer, J Zhao, ZY Lin… - Small (Weinheim an …, 2015 - europepmc.org
A smart, tumor-trigged, controlled drug release using inorganic" caps" with CO3 (2-) functional
groups in electrospun fibers is presented for inhibiting cancer relapse. When the drug-…

Doxorubicin-loaded mesoporous silica nanoparticle composite nanofibers for long-term adjustments of tumor apoptosis

Z Yuan, Y Pan, R Cheng, L Sheng, W Wu, G Pan… - …, 2016 - iopscience.iop.org
There is a high local recurrence (LR) rate in breast-conserving therapy (BCT) and enhancement
of the local treatment is promising as a way to improve this. Thus we propose a drug …

Targeted thrombolysis by using of magnetic mesoporous silica nanoparticles

M Wang, J Zhang, Z Yuan, W Yang… - Journal of biomedical …, 2012 - ingentaconnect.com
Thrombolytics inevitably led to the risk of hemorrhagic complications due to their non-specific
plasminogen activation in treatment of thrombosis. The aim of this study was to determine …

[HTML][HTML] Integrated analyses of microRNA and mRNA expression profiles in aggressive papillary thyroid carcinoma

Z Yang, Z Yuan, Y Fan, X Deng… - Molecular medicine …, 2013 - spandidos-publications.com
microRNAs (miRNAs) are involved in the pathogenesis of diverse human cancers through
its target genes, including papillary thyroid cancer (PTC). However, there are few studies …

Ibuprofen-loaded electrospun fibrous scaffold doped with sodium bicarbonate for responsively inhibiting inflammation and promoting muscle wound healing in vivo

Z Yuan, J Zhao, W Zhu, Z Yang, B Li, H Yang… - Biomaterials …, 2014 - pubs.rsc.org
Infection or inflammation can cause the in vivo microenvironment to become acidic, and an
inappropriately excessive inflammatory response can significantly delay the healing process. …

[HTML][HTML] LncRNA NEAT1 remodels chromatin to promote the 5-Fu resistance by maintaining colorectal cancer stemness

Y Zhu, H Hu, Z Yuan, Q Zhang, H Xiong, Z Hu… - Cell Death & …, 2020 - nature.com
Resistance of chemotherapy is one of causes of recurrence and poor prognosis in patients
with colorectal cancer (CRC). The role of differentially expressed long non-coding RNA (…

[HTML][HTML] Colorectal cancer cell intrinsic fibroblast activation protein alpha binds to Enolase1 and activates NF-κB pathway to promote metastasis

Z Yuan, H Hu, Y Zhu, W Zhang, Q Fang, T Qiao… - Cell death & …, 2021 - nature.com
Fibroblast activation protein alpha (FAP) is a marker of cancer-associated fibroblast, which
is also expressed in cancer epithelial cells. However, the role of FAP in colorectal cancer (…

[HTML][HTML] Genome-wide discovery of circulating cell-free DNA methylation biomarkers for colorectal cancer detection

Q Fang, Z Yuan, H Hu, W Zhang, G Wang, X Wang - Clinical Epigenetics, 2023 - Springer
Background Colorectal polyp is known a precursor of colorectal cancer (CRC) that holds an
increased risk for progression to CRC. Circulating cell-free DNA (cfDNA) methylation has …

[HTML][HTML] Ang-(1-7) treatment attenuates lipopolysaccharide-induced early pulmonary fibrosis

Y Cao, Y Liu, J Shang, Z Yuan, F Ping, S Yao… - Laboratory …, 2019 - Elsevier
Early pulmonary fibrosis is the leading cause of poor prognosis in patients with acute respiratory
distress syndrome (ARDS). However, whether the renin-angiotensin system (RAS) can …