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Research ArticleOriginal Article
Open Access

Does serum calcium in pre-eclampsia and normal pregnancy differ?

Nasser O. Malas and Ziad M. Shurideh
Saudi Medical Journal October 2001, 22 (10) 868-871;
Nasser O. Malas
Department of Obstetrics & Gynecology, King Hussein Medical Centre, Fetal Medicine Sub-speciality at Queen Charlotte's Hospital, PO Box 352-11621, Amman, Jordan. Tel. +962 (6) 5856856.
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Ziad M. Shurideh
Department of Obstetrics & Gynecology, King Hussein Medical Centre, Fetal Medicine Sub-speciality at Queen Charlotte's Hospital, Amman, Jordan.
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Abstract

OBJECTIVE: To determine the calcium and parathyroid hormone levels in normal pregnancy and pregnancy induced hypertension.

METHODS: Eighty pregnant women were enrolled in this study, 50 women represented the study group (Pregnancy-induced hypertension), and 30 women represented the control group (normal pregnancy). This study was carried out between March 1998 to February 2000 at King Hussein Medical Center, starting from the first or 2nd trimester. Once the patient developed hypertension for the first time in the 3rd trimester and fullfilled the selected criteria she was enrolled in this study.

RESULTS: The mean serum total calcium of the study group was (8.22±0.12mg%), while the mean serum total calcium of the control group was (9.50±0.16mg%). There was a statistical significance between the 2 groups, lower in the study group P<0.005. Serum parathyroid hormone concentration was significantly higher in the study group P< 0.005.

CONCLUSION: It has been widely documented that there is a relationship between low calcium level and pregnancy induced hypertension. Our study suggests that maternal serum total calcium and parathyroid hormone be related to pregnancy-induced hypertension. The low level of maternal total calcium may have a role in the development of this disorder in pregnancy, therefore calcium supplementation during late pregnancy may be used to help in the prevention of this disorder. However, to date there is still no evidence regarding this supplementation and there are no available reports conclusively demonstrating the actual mechanism.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 22 (10)
Saudi Medical Journal
Vol. 22, Issue 10
1 Oct 2001
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Does serum calcium in pre-eclampsia and normal pregnancy differ?
Nasser O. Malas, Ziad M. Shurideh
Saudi Medical Journal Oct 2001, 22 (10) 868-871;

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Does serum calcium in pre-eclampsia and normal pregnancy differ?
Nasser O. Malas, Ziad M. Shurideh
Saudi Medical Journal Oct 2001, 22 (10) 868-871;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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