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Research ArticleOriginal Article
Open Access

Chloral hydrate. An effective agent for sedation in children with age and weight dependent response

Omar M. Hijazi, Nasser A. Haidar and Youssef A. Al-Eissa
Saudi Medical Journal May 2005, 26 (5) 746-749;
Omar M. Hijazi
Department of Pediatrics, King Fahad National Guard Hospital, PO Box 22490, Riyadh 11426, Kingdom of Saudi Arabia. Fax. +966 (1) 2520088 Ext. 1641. E-mail: [email protected]
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  • For correspondence: [email protected]
Nasser A. Haidar
Department of Pediatrics, King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia.
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Youssef A. Al-Eissa
Department of Pediatrics, King Fahad National Guard Hospital, Riyadh, Kingdom of Saudi Arabia.
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Abstract

OBJECTIVE: Diagnostic and therapeutic procedures in children are made easier using sedation. However, there is no consensus about which drug should be used to achieve this. Furthermore, none of the drugs used for sedation are risk free. The aim of this work is to study sedation indications, effectiveness, and safety at our center.

METHODS: A prospective observational study conducted at the Pediatric Day Care Unit, King Fahad National Guard Hospital, Riyadh, Saudi Arabia. The study covered 17.5 weeks in 2 periods: May 9th 1999 to June 13th 1999 and October 31st 2001 to February 11th 2002. Children <12 years were included. Collected data included demographics, indication, drug dosing and outcome. Data were reported as mean ± SD.

RESULTS: We included 148 patients, age 38 ± 30 months. Adequate sedation was achieved in 79% after initial chloral hydrate (CH) dose of 56.9 ± 9.3 mg/kg, in 95% after adding 18.5 ± 6.4mg/kg CH and in 96% after adding second drug. Compared to nonrespondents, first CH dose respondents were younger and lower in weight. The CH side effects were few and mild.

CONCLUSION: Chloral hydrate is a safe and effective agent for sedation in children with an age and weight dependent response.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 26 (5)
Saudi Medical Journal
Vol. 26, Issue 5
1 May 2005
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Chloral hydrate. An effective agent for sedation in children with age and weight dependent response
Omar M. Hijazi, Nasser A. Haidar, Youssef A. Al-Eissa
Saudi Medical Journal May 2005, 26 (5) 746-749;

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Chloral hydrate. An effective agent for sedation in children with age and weight dependent response
Omar M. Hijazi, Nasser A. Haidar, Youssef A. Al-Eissa
Saudi Medical Journal May 2005, 26 (5) 746-749;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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