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Research ArticleOriginal Article
Open Access

Evaluation of some essential element levels in thalassemia major patients in Mosul district, Iraq

Abdulmunaim H. Al-Samarrai, Mohaisen H. Adaay, Khudhair A. Al-Tikriti and Muayed M. Al-Anzy
Saudi Medical Journal January 2008, 29 (1) 94-97;
Abdulmunaim H. Al-Samarrai
Department of Biochemistry, College of Medicine, University of Tikrit, Tikrit, Iraq.
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Mohaisen H. Adaay
Department of Biochemistry, College of Medicine, University of Tikrit, Tikrit, Iraq.
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Khudhair A. Al-Tikriti
Department of Biochemistry, College of Medicine, University of Tikrit, Tikrit, Iraq.
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Muayed M. Al-Anzy
Department of Biochemistry, College of Medicine, University of Tikrit, Tikrit, Iraq.
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Abstract

OBJECTIVE: To evaluate the levels of some essential elements in thalassemic patients in Mosul, Iraq.

METHODS: One hundred and five thalassemic blood transfusion dependent children, 2.5-18 years of age attending Ibn-Al-Atheer teaching hospital in Mosul City, Iraq, during 2005, were used in this study. Fifty-four healthy subjects served as a control group. Patients were allocated in a non-randomized prospective cross-sectional hospital based study. Essential elements levels were estimated. The mean, standard deviation, correlation coefficient, and z-test were used. P-values <0.05 were considered statistically significant.

RESULTS: Low serum zinc, and magnesium, and high serum copper, and potassium levels were found among the 105 thalassemic patients compared to the 54 controls. Levels of calcium, phosphate, and sodium were within normal limits.

CONCLUSION: Fluctuations in the essential elements levels seem to be related to the different complications associated with the disease. Zinc deficiency may be attributed to hyperzincuria resulted from the release of Zn from hemolyzed red cells. Hypercupremia occurs in acute and chronic infections and hemochromatosis, which is a principal complication of thalassemia. Increased Na levels may be due to renal damage. Hypomagnesemia may occur due to hypoparathyroidism.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 29 (1)
Saudi Medical Journal
Vol. 29, Issue 1
1 Jan 2008
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Evaluation of some essential element levels in thalassemia major patients in Mosul district, Iraq
Abdulmunaim H. Al-Samarrai, Mohaisen H. Adaay, Khudhair A. Al-Tikriti, Muayed M. Al-Anzy
Saudi Medical Journal Jan 2008, 29 (1) 94-97;

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Evaluation of some essential element levels in thalassemia major patients in Mosul district, Iraq
Abdulmunaim H. Al-Samarrai, Mohaisen H. Adaay, Khudhair A. Al-Tikriti, Muayed M. Al-Anzy
Saudi Medical Journal Jan 2008, 29 (1) 94-97;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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