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Research ArticleOriginal Article
Open Access

Tramadol as an adjuvant to intravenous regional anesthesia with lignocaine

Ahsan K. Siddiqui, Hany A. Mowafi, AbdulMohsin Al-Ghamdi, Salah A. Ismail and Haitham A. AbuZeid
Saudi Medical Journal August 2008, 29 (8) 1151-1155;
Ahsan K. Siddiqui
Department of Anesthesiology, King Fahd Teaching Hospital, King Faisal University, PO Box 40081, Al-Khobar 31952, Kingdom of Saudi Arabia. Tel. +966 502085613. Fax. +966 (3) 8823650. E-mail: [email protected]
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Hany A. Mowafi
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AbdulMohsin Al-Ghamdi
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Salah A. Ismail
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Haitham A. AbuZeid
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Abstract

OBJECTIVE: To assess the effect of different doses of tramadol when added to lignocaine during intravenous regional anesthesia (IVRA).

METHODS: Sixty patients, scheduled for hand surgery under IVRA in King Fahd University Hospital, Al-Khobar, Saudi Arabia from January 2006 to January 2007 were randomly allocated into 3 groups (20 patients each) in a double blind controlled study. All patients received 0.5% lignocaine, 40ml plus 2ml of a study solution containing either isotonic saline control group, or tramadol 50mg (group T50) or tramadol 100 mg (group T100). Hemodynamic changes, sensory and motor block onset and recovery times, tourniquet tolerance time, the quality of intraoperative anesthesia and the duration of postoperative analgesia were assessed.

RESULTS: All patients, 20 in each group completed the study period. Patients who received tramadol had earlier onset of sensory block (5.2 +/= 1.2; 4.9 +/= 1.2 min in the T50; and T100 groups) compared with the control group (7.6 +/= 1.4 min). Patients who received 100mg of tramadol had better tolerance of tourniquet (p=0.011), and less intraoperative fentanyl supplementation (p=0.042). They had also a longer time to the first postoperative analgesic request (p=0.001) compared with the control group.

CONCLUSION: Tramadol 100 mg is a beneficial additive to lignocaine for IVRA since it shortened the onset of sensory block, enhanced the tourniquet tolerance and improved the perioperative analgesia.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 29 (8)
Saudi Medical Journal
Vol. 29, Issue 8
1 Aug 2008
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Tramadol as an adjuvant to intravenous regional anesthesia with lignocaine
Ahsan K. Siddiqui, Hany A. Mowafi, AbdulMohsin Al-Ghamdi, Salah A. Ismail, Haitham A. AbuZeid
Saudi Medical Journal Aug 2008, 29 (8) 1151-1155;

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Tramadol as an adjuvant to intravenous regional anesthesia with lignocaine
Ahsan K. Siddiqui, Hany A. Mowafi, AbdulMohsin Al-Ghamdi, Salah A. Ismail, Haitham A. AbuZeid
Saudi Medical Journal Aug 2008, 29 (8) 1151-1155;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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