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Review ArticleReview Article
Open Access

Molecular nature of alpha-globin genes in the Saudi population

J. Francis Borgio
Saudi Medical Journal November 2015, 36 (11) 1271-1276; DOI: https://doi.org/10.15537/smj.2015.11.12704
J. Francis Borgio
From the Center for Research and Medical Consultation, University of Dammam, Dammam, Kingdom of Saudi Arabia
MSc, PhD
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    Figure 1

    An image showing 3 types of globin genes prevalent in the Saudi population: HBA2 (α2), HBA1 (α1), and HBA12 (α12). The α2 gene is colored in nut brown and α1 gene is colored in violet. The undistinguished sequences (α1 or α2 ?) are colored in black. Reproduced and modified from: Borgio JF, AbdulAzeez S, Al-Nafie AN, Naserullah ZA, Al-Jarrash S, Al-Madan MS, et al. A novel HBA2 gene conversion in cis or trans: “α12 allele” in a Saudi population. Blood Cells Mol Dis 2014; 53: 199-203.8 With permission from Elsevier.

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    Figure 2

    Molecular types of thalassemia and types of globin gene deletions prevalent in the Saudi population. Filled boxes of genes α1, α2, and α12 indicates normal genes, while empty boxes of genes α1, α2, and α12 indicate the deleted genes.

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Saudi Medical Journal: 36 (11)
Saudi Medical Journal
Vol. 36, Issue 11
1 Nov 2015
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Molecular nature of alpha-globin genes in the Saudi population
J. Francis Borgio
Saudi Medical Journal Nov 2015, 36 (11) 1271-1276; DOI: 10.15537/smj.2015.11.12704

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Molecular nature of alpha-globin genes in the Saudi population
J. Francis Borgio
Saudi Medical Journal Nov 2015, 36 (11) 1271-1276; DOI: 10.15537/smj.2015.11.12704
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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