Review ArticleReview Article
Open Access

Current techniques of lamellar keratoplasty for keratoconus

Leopoldo Spadea and Victoria De Rosa
Saudi Medical Journal February 2016, 37 (2) 127-136; DOI: https://doi.org/10.15537/smj.2016.2.12985

References

  1. ↵
    1. Jhanji V,
    2. Sharma N,
    3. Vajpayee RB
    (2011) Management of keratoconus: current scenario. Br J Ophthalmol 95:1044–1050.
    OpenUrlAbstract/FREE Full Text
    1. Spadea L,
    2. Bianco G,
    3. Mastrofini MC,
    4. Balestrazzi E
    (1996) Penetrating keratoplasty with donor and recipient corneas of the same diameter. Ophthalmic Surg Lasers 27:425–430.
    OpenUrlPubMed
  3. ↵
    1. Arenas E,
    2. Esquenazi S,
    3. Anwar M,
    4. Terry M
    (2012) Lamellar corneal transplantation. Surv Ophthalmol 57:510–529.
    OpenUrlPubMed
  4. ↵
    1. Zhang YM,
    2. Wu SQ,
    3. Yao YF
    (2013) Long-term comparison of full-bed deep anterior lamellar keratoplasty and penetrating keratoplasty in treating keratoconus. J Zhejiang Univ Sci B 14:438–450.
    OpenUrlCrossRefPubMed
  5. ↵
    1. Coster DJ,
    2. Lowe MT,
    3. Keane MC,
    4. Williams KA
    (2014) Australian Corneal Graft Registry Contributors. A comparison of lamellar and penetrating keratoplasty outcomes: a registry study. Ophthalmology 121:978–987.
    OpenUrl
  6. ↵
    1. Reinhart WJ,
    2. Musch DC,
    3. Jacobs DS,
    4. Lee WB,
    5. Kaufman S,
    6. Shtein RM
    (2011) Deep anterior lamellar keratoplasty as an alternative to penetrating keratoplasty a report by the american academy of ophthalmology. Ophthalmology 118:209–218.
    OpenUrlCrossRefPubMedWeb of Science
  7. ↵
    1. Fasolo A,
    2. Frigo AC,
    3. Böhm E,
    4. Genisi C,
    5. Rama P,
    6. Spadea L,
    7. et al.
    (2006) The CORTES study: corneal transplant indications and graft survival in an Italian cohort of patients. Cornea 25:507–515.
    OpenUrlCrossRefPubMed
  8. ↵
    1. Liu H,
    2. Chen Y,
    3. Wang P,
    4. Li B,
    5. Wang W,
    6. Su Y,
    7. et al.
    (2015) Efficacy and safety of deep anterior lamellar keratoplasty vs. penetrating keratoplasty for keratoconus: a meta-analysis. PLoS One 10:e0113332.
    OpenUrl
  9. ↵
    1. Abdelkader A
    (2013) Influence of different keratoplasty techniques on the biomechanical properties of the cornea. Acta Ophthalmol 91:e567–e572.
    OpenUrl
  10. ↵
    1. Tan DT,
    2. Ang LP
    (2004) Automated lamellar therapeutic keratoplasty for post-PRK corneal scarring and thinning. Am J Ophthalmol 138:1067–1069.
    OpenUrlCrossRefPubMed
  11. ↵
    1. Jiménez-Alfaro I,
    2. Pérez-Santonja JJ,
    3. Gómez Tellería G,
    4. Bueno Palacín JL,
    5. Puy P
    (2001) Therapeutic lamellar keratoplasty with an automated microkeratome. J Cataract Refract Surg 27:1161–1165.
    OpenUrlCrossRefPubMed
    1. Tan DTH,
    2. Ang LP
    (2006) Modified automated lamellar therapeutic keratoplasty for keratoconus: a new technique. Cornea 25:1217–1219.
    OpenUrlCrossRefPubMed
  13. ↵
    1. Acar BT,
    2. Arslan OS,
    3. Buttanri IB,
    4. Sevim MS,
    5. Acar S
    (2011) Comparing deep anterior lamellar keratoplasty and automated lamellar therapeutic keratoplasty in patients with keratoconus. Jpn J Ophthalmol 55:327–332.
    OpenUrlPubMed
  14. ↵
    1. Bilgihan K,
    2. Ozdek SC,
    3. Sari A,
    4. Hasanreisoglu B
    (2003) Microkeratome-assisted lamellar keratoplasty for keratoconus: stromal sandwich. J Cataract Refract Surg 29:1267–1272.
    OpenUrlPubMed
  15. ↵
    1. Busin M,
    2. Zambianchi L,
    3. Arffa RC
    (2005) Microkeratome-assisted lamellar keratoplasty for the surgical treatment of keratoconus. Ophthalmology 112:987–997.
    OpenUrlCrossRefPubMedWeb of Science
  16. ↵
    1. Busin M,
    2. Scorcia V,
    3. Zambianchi L,
    4. Ponzin D
    (2012) Outcomes from a modified microkeratome-assisted lamellar keratoplasty for keratoconus. Arch Ophthalmol 130:776–782.
    OpenUrlPubMed
  17. ↵
    1. Buratto L,
    2. Belloni S,
    3. Valeri R
    (1998) Excimer laser lamellar keratoplasty of augmented thickness for keratoconus. J Refract Surg 14:517–525.
    OpenUrlPubMed
  18. ↵
    1. Serdarevic ON,
    2. Hanna K,
    3. Gribomont AC,
    4. Savoldelli M,
    5. Renard G,
    6. Pouliquen Y
    (1988) Excimer laser trephination in penetrating keratoplasty. Morphologic features and wound healing. Ophthalmology 95:493–505.
    OpenUrlPubMedWeb of Science
  19. ↵
    1. Kubota T,
    2. Seitz B,
    3. Tetsumoto K,
    4. Naumann GO
    (1992) Lamellar excimer laser keratoplasty: reproducible photoablation of corneal tissue. A laboratory study. Doc Ophthalmol 82:193–200.
    OpenUrlPubMed
  20. ↵
    1. Bilgihan K,
    2. Ozdek SC,
    3. Sari A,
    4. Hasanreisoğlu B
    (2006) Excimer laser-assisted anterior lamellar keratoplasty for keratoconus, corneal problems after laser in situ keratomileusis, and corneal stromal opacities. J Cataract Refract Surg 32:1264–1269.
    OpenUrlCrossRefPubMed
  21. ↵
    1. Spadea L,
    2. Giammaria D,
    3. Fiasca A,
    4. Verrecchia V
    (2009) Excimer laser-assisted lamellar keratoplasty for the surgical treatment of keratoconus. J Cataract Refract Surg 35:105–112.
    OpenUrlPubMed
  22. ↵
    1. Spadea L,
    2. Gizzi R,
    3. Evangelista Conocchia N,
    4. Urbano S
    (2012) Optical pachymetry-guided custom excimer laser-assisted lamellar keratoplasty for the surgical treatment of keratoconus. J Cataract Refract Surg 38:1559–1567.
    OpenUrlPubMed
  23. ↵
    1. Spadea L
    (2012) Collagen crosslinking for ectasia following PRK performed in excimer laser-assisted keratoplasty for keratoconus. Eur J Ophthalmol 22:274–277.
    OpenUrlPubMed
  24. ↵
    1. Spadea L,
    2. Paroli M
    (2012) Simultaneous topography-guided PRK followed by corneal collagen cross-linking after lamellar keratoplasty for keratoconus. Clin Ophthalmol 6:1793–1800.
    OpenUrlPubMed
  25. ↵
    1. Hou P,
    2. Lu Y,
    3. Ye F,
    4. Lan W,
    5. Huang Z
    (2013) Application of femtosecond laser in ocular surgery. Eye Sci 28:103–107.
    OpenUrl
  26. ↵
    1. Farid M,
    2. Steinert RF
    (2010) Femtosecond laser-assisted corneal surgery. Curr Opin Ophtahalmol 21:288–292.
    OpenUrl
  27. ↵
    1. Jones YJ,
    2. Goins KM,
    3. Sutphin JE,
    4. Mullins R,
    5. Skeie JM
    (2008) Comparison of the femtosecond laser (IntraLase) versus manual microkeratome (Moria ALTK) in dissection of the donor in endothelial keratoplasty: initial study in eye bank eyes. Cornea 27:88–93.
    OpenUrlCrossRefPubMedWeb of Science
  28. ↵
    1. Almousa R,
    2. Samaras KE,
    3. Khan S,
    4. Lake DB,
    5. Daya SM
    (2014) Femtosecond laser-assisted lamellar keratoplasty (FSLK) for anterior corneal stromal diseases. Int Ophthalmol 34:49–58.
    OpenUrl
  29. ↵
    1. Flanagan GW,
    2. Binder PS
    (2003) Precision of flap measurements for laser in situ keratomileusis in 4428 eyes. J Refract Surg 19:113–123.
    OpenUrlPubMedWeb of Science
    1. Kezirian GM,
    2. Stonecipher KG
    (2004) Comparison of the IntraLase femtosecond laser and mechanical keratomes for laser in situ keratomileusis. J Cataract Refract Surg 30:804–811.
    OpenUrlCrossRefPubMedWeb of Science
  31. ↵
    1. Binder PS
    (2004) Flap dimensions created with the IntraLase FS laser. J Cataract Refract Surg 30:26–32.
    OpenUrlCrossRefPubMedWeb of Science
  32. ↵
    1. Mosca L,
    2. Fasciani R,
    3. Tamburelli C,
    4. Buzzonetti L,
    5. Guccione L,
    6. Mandarà E,
    7. et al.
    (2008) Femtosecond laser-assisted lamellar keratoplasty: early results. Cornea 27:668–672.
    OpenUrlCrossRefPubMed
    1. Baradaran-Rafii A,
    2. Eslani M
    (2013) Femtosecond laser assisted corneal transplantation. Br J Ophthalmol 97:675–676.
    OpenUrlFREE Full Text
    1. Hoffart L,
    2. Proust H,
    3. Matonti F,
    4. Catanèse M,
    5. Conrath J,
    6. Ridings B
    (2007) [Femtosecond-assisted anterior lamellar keratoplasty]. J Fr Ophthalmol 30:689–694, French.
    OpenUrlPubMed
    1. Hou P,
    2. Lu Y,
    3. Ye F,
    4. Lan W,
    5. Huang Z
    (2013) Application of femtosecond laser in ocular surgery. Eye Sci 28:103–107.
    OpenUrl
  36. ↵
    1. Shousha MA,
    2. Yoo SH,
    3. Kymionis GD,
    4. Ide T,
    5. Feuer W,
    6. Karp CL,
    7. et al.
    (2011) Long-term results of femtosecond laser-assisted sutureless anterior lamellar keratoplasty. Ophthalmology 118:315–323.
    OpenUrlPubMed
  37. ↵
    1. Yoo SH,
    2. Kymionis GD,
    3. Koreishi A,
    4. Ide T,
    5. Goldman D,
    6. Karp CL,
    7. et al.
    (2008) Femtosecond laser–assisted sutureless anterior lamellar keratoplasty. Ophthalmology 115:1303–1307, 1307.e1.
    OpenUrlCrossRefPubMedWeb of Science
  38. ↵
    1. Chan CC,
    2. Ritenour RJ,
    3. Kumar NL,
    4. Sansanayudh W,
    5. Rootman DS
    (2010) Femtosecond laser-assisted mushroom configuration deep anterior lamellar keratoplasty. Cornea 29:290–295.
    OpenUrlCrossRefPubMed
  39. ↵
    1. Anwar M
    (1972) Dissection technique in lamellar keratoplasty. Br J Ophthalmol 56:711–713.
    OpenUrlFREE Full Text
  40. ↵
    1. Sarnicola V,
    2. Toro P,
    3. Sarnicola C,
    4. Sarnicola E,
    5. Ruggiero A
    (2012) Long-term graft survival in deep anterior lamellar keratoplasty. Cornea 31:621–626.
    OpenUrlCrossRefPubMedWeb of Science
  41. ↵
    1. Sugita J,
    2. Kondo J
    (1997) Deep lamellar keratoplasty with complete removal of pathological stroma for vision improvement. Br J Ophthalmol 81:184–188.
    OpenUrlAbstract/FREE Full Text
  42. ↵
    1. Marchini G,
    2. Mastropasqua L,
    3. Pedrotti E,
    4. Nubile M,
    5. Ciancaglini M,
    6. et al.
    (2006) Deep lamellar keratoplasty by intracorneal dissection: a prospective clinical and confocal microscopic study. Ophthalmology 113:1289–1300.
    OpenUrlCrossRefPubMedWeb of Science
  43. ↵
    1. Ardjomand N,
    2. Hau S,
    3. McAlister JC,
    4. Bunce C,
    5. Galaretta D,
    6. Tuft SJ,
    7. et al.
    (2007) Quality of vision and graft thickness in deep anterior lamellar and penetrating corneal allografts. Am J Ophthalmol 143:228–235.
    OpenUrlCrossRefPubMedWeb of Science
  44. ↵
    1. Rama P,
    2. Knutsson KA,
    3. Razzoli G,
    4. Matuska S,
    5. Viganò M,
    6. Paganoni G
    (2013) Deep anterior lamellar keratoplasty using an original manual technique. Br J Ophthalmol 97:23–27.
    OpenUrlAbstract/FREE Full Text
  45. ↵
    1. Oh BL,
    2. Kim MK,
    3. Wee WR
    (2013) Comparison of clinical outcomes of same-size grafting between deep anterior lamellar keratoplasty and penetrating keratoplasty for keratoconus. Korean J Ophthalmol 27:322–330.
    OpenUrlCrossRefPubMed
  46. ↵
    1. Sarnicola V,
    2. Toro P,
    3. Gentile D,
    4. Hannush SB
    (2010) Descemetic DALK and predescemetic DALK: outcomes in 236 cases of keratoconus. Cornea 29:53–59.
    OpenUrlCrossRefPubMedWeb of Science
    1. Fontana L,
    2. Parente G,
    3. Sincich A,
    4. Tassinari G
    (2011) Influence of graft-host interface on the quality of vision after deep anterior lamellar keratoplasty in patients with keratoconus. Cornea 30:497–502.
    OpenUrlPubMedWeb of Science
  48. ↵
    1. Schiano-Lomoriello D,
    2. Colabelli-Gisoldi RA,
    3. Nubile M,
    4. Oddone F,
    5. Ducoli G,
    6. Villani CM,
    7. et al.
    (2014) Descemetic and predescemetic DALK in keratoconus patients: a clinical and confocal perspective study. Biomed Res Int 2014:123156.
    OpenUrl
  49. ↵
    1. Chew AC,
    2. Mehta JS,
    3. Tan DT
    (2011) Deep lamellar keratoplasty after resolution of hydrops in keratoconus. Cornea 30:454–459.
    OpenUrlCrossRefPubMed
  50. ↵
    1. Anwar HM,
    2. Anwar M
    (2011) Predescemetic dissection for healed hydrops--judicious use of air and fluid. Cornea 30:1502–1509.
    OpenUrlCrossRefPubMed
  51. ↵
    1. Tan DT,
    2. Dart JK,
    3. Holland EJ,
    4. Kinoshita S
    (2012) Corneal transplantation. Lancet 379:1749–1761.
    OpenUrlCrossRefPubMedWeb of Science
  52. ↵
    1. Tan DT,
    2. Anshu A
    (2010) Anterior lamellar keratoplasty: ‘Back to the Future’- a review. Clin Experiment Ophthalmol 38:118–127.
    OpenUrlPubMed
  53. ↵
    1. Archila EA
    (1984-1985) Deep lamellar keratoplasty dissection of host tissue with intrastromal air injection. Cornea 3:217–218.
    OpenUrlPubMed
  54. ↵
    1. Panda A,
    2. Singh R
    (2000) Intralamellar dissection techniques in lamellar keratoplasty. Cornea 19:22–25.
    OpenUrlCrossRefPubMed
  55. ↵
    1. Tsubota K,
    2. Kaido M,
    3. Monden Y,
    4. Satake Y,
    5. Bissen-Miyajima H,
    6. Shimazaki J
    (1998) A new surgical technique for deep lamellar keratoplasty with single running suture adjustment. Am J Ophthalmol 126:1–8.
    OpenUrlCrossRefPubMedWeb of Science
  56. ↵
    1. Manche EE,
    2. Holland GN,
    3. Maloney RK
    (1999) Deep lamellar keratoplasty using viscoelastic dissection. Arch Ophthalmol 117:1561–1565.
    OpenUrlCrossRefPubMedWeb of Science
  57. ↵
    1. Melles GR,
    2. Remeijer L,
    3. Geerards AJ,
    4. Beekhuis WH
    (2000) A quick surgical technique for deep, anterior lamellar keratoplasty using visco-dissection. Cornea 19:427–432.
    OpenUrlCrossRefPubMedWeb of Science
  58. ↵
    1. Bahar I,
    2. Kaiserman I,
    3. Srinivasan S,
    4. Ya-Ping J,
    5. Slomovic AR,
    6. Rootman DS
    (2008) Comparison of three different techniques of corneal transplantation for keratoconus. Am J Ophthalmol 146:905–912.e1.
    OpenUrlCrossRefPubMedWeb of Science
    1. MacIntyre R,
    2. Chow SP,
    3. Chan E,
    4. Poon A
    (2014) Long-term outcomes of deep anterior lamellar keratoplasty versus penetrating keratoplasty in Australian keratoconus patients. Cornea 33:6–9.
    OpenUrlCrossRefPubMed
  60. ↵
    1. Cano-Ortiz A,
    2. Villarrubia A
    (2015) [Corneal transplantation in keratoconus: penetrating keratoplasty versus deep anterior lamellar keratoplasty with Melles technique]. Arch Soc Esp Oftalmol 90:4–8, Spanish.
    OpenUrl
  61. ↵
    1. Anwar M,
    2. Teichmann KD
    (2002) Big-bubble technique to bare Descemet’s membrane in anterior lamellar keratoplasty. J Cataract Refract Surg 28:398–403.
    OpenUrlCrossRefPubMedWeb of Science
  62. ↵
    1. Al-Torbak AA,
    2. Al-Motowa S,
    3. Al-Assiri A,
    4. Al-Kharashi S,
    5. Al-Shahwan S,
    6. Al-Mezaine H,
    7. et al.
    (2006) Deep anterior lamellar keratoplasty for keratoconus. Cornea 25:408–412.
    OpenUrlPubMedWeb of Science
    1. Fogla R,
    2. Padmanabhan P
    (2006) Results of deep lamellar keratoplasty using the big-bubble technique in patients with keratoconus. Am J Ophthalmol 141:254–259.
    OpenUrlCrossRefPubMedWeb of Science
    1. Fontana L,
    2. Parente G,
    3. Tassinari G
    (2007) Clinical outcomes after deep anterior lamellar keratoplasty using the big-bubble technique in patients with keratoconus. Am J Ophthalmol 143:117–124.
    OpenUrlCrossRefPubMed
  65. ↵
    1. Feizi S,
    2. Javadi MA,
    3. Jamali H,
    4. Mirbabaee F
    (2010) Deep anterior lamellar keratoplasty in patients with keratoconus: big-bubble technique. Cornea 29:177–182.
    OpenUrlCrossRefPubMedWeb of Science
    1. Romano V,
    2. Iovieno A,
    3. Parente G,
    4. Soldani AM,
    5. Fontana L
    (2015) Long-term clinical outcomes of deep anterior lamellar keratoplasty in patients with keratoconus. Am J Ophthalmol 159:505–511.
    OpenUrl
  67. ↵
    1. Khakshoor H,
    2. Eslampoor A,
    3. Rad SS,
    4. Vejdani A
    (2014) Modified deep anterior lamellar keratoplasty for the treatment of advanced keratoconus with steep corneal curvature to help in eliminating the wrinkles in the Descemet’s membrane. Indian J Ophthalmol 62:392–395.
    OpenUrl
  68. ↵
    1. Ghanem RC,
    2. Bogoni A,
    3. Ghanem VC
    (2015) Pachymetry-guided intrastromal air injection (“pachy-bubble”) for deep anterior lamellar keratoplasty: results of the first 110 cases. Cornea 34:625–631.
    OpenUrl
  69. ↵
    1. Yao YF
    (2008) A novel technique for performing full-bed deep lamellar keratoplasty. Cornea 27(Suppl 1):S19–S24.
    OpenUrl
  70. ↵
    1. Dua HS,
    2. Faraj LA,
    3. Said DG,
    4. Gray T,
    5. Lowe J
    (2013) Human corneal anatomy redefined: a novel pre-Descemet’s layer (Dua’s layer). Ophthalmology 120:1778–1785.
    OpenUrlCrossRefPubMedWeb of Science
  71. ↵
    1. Farid M,
    2. Steinert RF
    (2009) Deep anterior lamellar keratoplasty performed with the femtosecond laser zigzag incision for the treatment of stromal corneal pathology and ectatic disease. J Cataract Refract Surg 35:809–813.
    OpenUrlCrossRefPubMed
  72. ↵
    1. Buzzonetti L,
    2. Laborante A,
    3. Petrocelli G
    (2010) Standardized big-bubble technique in deep anterior lamellar keratoplasty assisted by the femtosecond laser. J Cataract Refract Surg 36:1631–1636.
    OpenUrlCrossRefPubMed
  73. ↵
    1. Buzzonetti L,
    2. Petrocelli G,
    3. Valente P
    (2012) Femtosecond laser and big-bubble deep anterior lamellar keratoplasty: a new chance. J Ophthalmol 2012:264590.
    OpenUrlPubMed
  74. ↵
    1. Tan DTH,
    2. Mehta JS
    (2007) Future directions in lamellar corneal transplantation. Cornea 26(9 Suppl 1):S21–S28.
    OpenUrlCrossRefPubMedWeb of Science
  75. ↵
    1. Sarnicola V,
    2. Toro P
    (2011) Blunt cannula for descemetic deep anterior lamellar keratoplasty. Cornea 30:985–988.
    OpenUrl
  76. ↵
    1. Urrets-Zavalia A
    (1963) Fixed dilated pupil, iris atrophy and secondary glaucoma: a distinct clinical entity following penetrating keratoplasty for keratoconus. Am J Ophthalmol 56:257–265.
    OpenUrlCrossRefPubMed
Back to top

In this issue

Print
Download PDF
Email Article
Citation Tools
Bookmark this article

Jump to section