Research ArticleOriginal Article
Open Access

Impact of cyclooxygenase-2 over-expression on the prognosis of colorectal cancer patients

An experience from Western Saudi Arabia

Abdulkader M. Albasri, Mohammed A. Elkablawy, Akbar S. Hussainy, Hala M. Yousif and Ahmed S. Alhujaily
Saudi Medical Journal August 2018, 39 (8) 773-780; DOI: https://doi.org/10.15537/smj.2018.8.22837

Article Figures & Data

Figures

  • Figure 1
    Figure 1

    Different patterns of immunohistochemical COX-2 expression in A) normal colon (weak cytoplasmic positivity), B) colonic adenoma (mild to moderate cytoplasmic positivity), C) colorectal carcinoma (marked granular cytoplasmic expression), and D) lymph node metastasis CRC (marked granular cytoplasmic expression). Arrows indicate COX-2 cytoplasmic expression.

  • Figure 2
    Figure 2

    Immunohistochemical characterization of colorectal cancer specimens showing high levels of Ki67 expression confirming the association between increased (+++) COX-2 immunoexpression and increased (+++) Ki67 immunoexpression. Arrows indicate COX-2 cytoplasmic expression and Ki67 nuclear expression.

  • Figure 3
    Figure 3

    Shows Kaplan-meier curves for significant overall survival functions for Cox2 expression in CRC.

Tables

  • Table 1
  • Table 2
  • Table 3
Back to top

In this issue

Print
Download PDF
Email Article
Citation Tools
Bookmark this article

Jump to section