Post-vaccination survey for monitoring the side effects associated with COVID-19 vaccines among healthcare professionals of Jazan province, Saudi Arabia

Article Figures & Data

Table 1

- Participants’ socio-demographics.

Variable	n (%)
Exact age, mean±SD	34.43±6.73
Gender
Male	209 (52.6)
Female	188 (47.4)
Age group (in years)
27-36	306 (77.1)
37-46	68 (17.1)
47-56	23 (5.8)
Nationality
Saudi	201 (50.6)
Non-Saudi	196 (49.4)
*Education qualification*
Bachelors	260 (65.5)
Masters	101 (25.4)
PhD	36 (9.1)
Occupation
Physician	87 (21.9)
Pharmacist	178 (44.8)
Nurse	59 (14.9)
Teacher/preceptor	22 (5.5)
Other health care professional	51 (12.8)

Table 2

- Descriptive statistics of vaccine related side effects.

Variables	n (%)
Severity of vaccine related side effects
Major	57 (14.4)
Minor	238 (59.9)
No side effect reported	102 (25.7)
Minor side effects
Low grade fever, chills & headache	85 (35.7)
Pain at the injection site	73 (30.7)
Myalgia and arthralgia	33 (13.9)
Fatigue & tiredness	47 (19.6)
Major side effects
High grade fever	47 (82.4)
Dyspnea	8 (14.0)
Anxiety	2 (3.5)
Timeline after which the side effects were experienced
<12 hours	23 (7.8)
12-24 hours	234 (79.3)
24-48 hours	38 (12.9)
Medical assistance due to minor side effects
Yes	0 (0.0)
No	238 (100)
Medical assistance due to major side effects
Yes	7 (12.3)
No	50 (87.7)
Medication taken to treat minor side effects
Yes	172 (72.2)
No	66 (27.7)
Medication taken to treat major side effects
Yes	57 (100)
No	0 (0.0)
Complete recovery after medical assistance
Yes	7 (100)
No	0 (0.0)
Days to recover after medical assistance
1-2	5 (71.4)
>2	2 (28.6)

Table 3

- Cross tabulations of the severity of side effects with sample characteristics.

Variables	No side effect reported	Minor	Major	Chi-square (χ²)	P-value
Gender
Male	89 (42.6)	106 (50.7)	14 (6.7)	73.32	<0.001
Female	13 (6.9)	132 (70.2)	43 (22.9)	73.32	<0.001
Age group (in years)
27-36	70 (22.9)	190 (62.1)	46 (15.0)	10.19	0.03*
37-46	24 (35.3)	33 (48.5)	11 (16.2)
47-56	8 (34.8)	15 (65.2)	0 (0.0)
Nationality
Saudi	70 (34.8)	114 (56.7)	17 (8.5)	23.80	<0.001
Non-Saudi	32 (16.3)	124 (63.3)	40 (20.4)	23.80	<0.001
Educational qualification
Bachelors degree	65 (25.0)	156 (60.0)	39 (15.0)	5.22	0.27
Masters degree	24 (23.8)	66 (65.3)	11 (10.9)
Doctorate	13 (36.1)	16 (44.4)	7 (19.4)
Occupation
Physician	26 (30.2)	52 (60.5)	8 (9.3)	10.60	0.10
Pharmacist	37 (21.6)	113 (66.1)	21 (12.3)
Nurse	18 (32.1)	27 (48.2)	11 (19.6)
Other HCP	21 (25.0)	46 (54.8)	17 (20.2)
Type of vaccine
Covishield (Oxford-AstraZeneca)	34 (11.7)	208 (71.5)	49 (16.8)	112.08	<0.001
Pfizer (Pfizer BioNTech)	68 (64.2)	30 (28.3)	8 (7.5)	112.08	<0.001
Comorbidities/current medical condition
Diabetes	4 (30.8)	8 (61.5)	1 (7.7)	3.68	0.72*
Hypertension/cardiac disorders	7 (43.8)	7 (43.8)	2 (12.5)
Others	7 (21.2)	22 (66.7)	4 (12.1)
No serious medical condition	84 (25.1)	201 (60.0)	50 (14.9)
Known allergies
No allergies	96 (27.8)	223 (64.6)	26 (7.5)	99.69	<0.001
Allergies present	6 (11.5)	15 (28.8)	31 (59.6)	99.69	<0.001
Current medications
Currently not on any medications	77 (21.5)	232 (64.8)	49 (13.7)	40.30	<0.001
Currently taking medications	25 (64.1)	6 (15.4)	8 (20.5)	40.30	<0.001
Previous COVID-19 infection
Yes	95 (27.1)	209 (59.7)	46 (13.1)	5.49	0.06
No	7 (14.9)	29 (61.7)	11 (23.4)	5.49	0.06

Values are presented as numbers and percentages (%). HCP: health care professional, * Fisher exact (p<0.05)

Table 4

- Binary logistic regression between severity of side effects and selected variables.

Determinants	AOR	95% CI		P-value
Determinants	AOR	Lower	Upper	P-value
Gender
Male	3.72	1.79	7.75	<0.001
Female				Ref
Name of the vaccine
Covishield	1.07	0.43	2.65	0.89
Pfizer				Ref
Known allergies
Yes	16.29	7.76	34.17	<0.001
No				Ref
Nationality
Saudi	2.51	1.24	5.09	0.01
Non-Saudi				(p<0.05) Ref