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Research ArticleOriginal Article
Open Access

The effect of COVID-19 vaccine on ovarian reserve

Çağanay Soysal and Elif Yılmaz
Saudi Medical Journal May 2022, 43 (5) 486-490; DOI: https://doi.org/10.15537/smj.2022.43.5.20220007
Çağanay Soysal
From the Department of Obstetrics and Gynecology, Dr. Sami Ulus Women’s and Children’s Health Teaching and Research Hospital, Ankara, Turkey.
MD, PhD
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Elif Yılmaz
From the Department of Obstetrics and Gynecology, Dr. Sami Ulus Women’s and Children’s Health Teaching and Research Hospital, Ankara, Turkey.
MD, PhD
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  • For correspondence: [email protected]
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    Table 1

    - Comparison of ages between groups.

    VariableExperimental group (n=30)Control group (n=30)Statistical analysis*
    Mean±SDMedian (min-max)Mean±SDMedian (min-max)Probability
    Age (years)27.30±1.6627.0 (25.0-30.0)27.40±1.6927.0 (25.0-30.0)Z= -0.233
    p=0.816
    • ↵* Mann-Whitney-U test (Z-table value) statistics were used to compare the measurement values of 2 independent groups that did not have a normal distribution. SD: standard deviation, min: minimum, max: maximum

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    Table 2

    - Examination of the relationships between the groups and certain characteristics (N=60).

    CharacteristicsExperimental group (n=30)Control group (n=30)Statistical analysis*
    Probability
    Educational status
    Primary school2 (6.7)1 (3.3) 
    High school16 (53.3)18 (60.0)χ2=0.494
    University12 (40.0)11 (36.7)p=0.781
    Employment
    Working21 (70.0)19 (63.3)χ2=0.075
    Not working9 (30.0)11 (36.7)p=0.784
    Marital status
    Married7 (23.3)5 (16.7)χ2=0.104
    Single23 (76.7)25 (83.3)p=0.747
    Partner’s employment status
    Working21 (91.3)22 (88.0)χ2=0.140
    Not working2 (8.7)3 (12.0)p=0.708

    Values are presented as a number and (%). *Continuity correction or Pearson-χ2 crosstabs were used according to the expected value levels in examining the relationship between 2 qualitative variables.

      • View popup
      Table 3

      - Comparison of anti-müllerian hormone values in terms of process according to groups (N=60).

      VariableSample (n=30)Control (n=30)Statistical analysis*
      Mean±SDMedian (min-max)Mean±SDMedian (min-max)Probability
      AMH
      Pre-test4.17±1.874.2 (0.9-7.9)4.14±2.793.5 (0.6-11.5)Z= -0.843, p=0.399
      Post-test4.13±1.944.3 (0.8-7.9)4.14±2.793.5 (0.6-11.5)Z= -0.591, p=0.554
      Statistical analysis (probability)t=0.275Z=0.000
      p=0.785p=1.000
      • ↵* Paired sample t-test (t-table value), Mann-Whitney-U test (Z-table value), and Wilcoxon test (Z-table value) statistics were used. AMH: anti-müllerian hormone, SD: standard deviation, min: minimum, max: maximum

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    Saudi Medical Journal: 43 (5)
    Saudi Medical Journal
    Vol. 43, Issue 5
    1 May 2022
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    The effect of COVID-19 vaccine on ovarian reserve
    Çağanay Soysal, Elif Yılmaz
    Saudi Medical Journal May 2022, 43 (5) 486-490; DOI: 10.15537/smj.2022.43.5.20220007

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    The effect of COVID-19 vaccine on ovarian reserve
    Çağanay Soysal, Elif Yılmaz
    Saudi Medical Journal May 2022, 43 (5) 486-490; DOI: 10.15537/smj.2022.43.5.20220007
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    Keywords

    • mRNA
    • vaccine
    • ovarian reserve
    • AMH
    • COVID-19

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