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Effects of mechanical forces on the formation of cutaneous wounds during skin expansion and emerging therapies for wound healing and scar prevention

Jiménez Ibañez E. Oswaldo, Domenico Tripodi, Yousuf Al-Shaqsi, Oscar E. Flores Woods and Rodrigo Valero
Saudi Medical Journal January 2023, 44 (1) 106-109; DOI: https://doi.org/10.15537/smj.2023.44.1.20220556

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Figures

  • Figure 1
    Figure 1

    - Histology of a scar following treatment with Cicolea. The epidermis has recovered a normal thickness and a regular organization with epidermal crests separated by superficial dermal papillae. The deeper dermis contains organized collagen fibers, which are still relatively thick in comparison to a normal dermis but are not hyalinized (x10).

  • Figure 2
    Figure 2

    - Histology of a scar following petrolatum treatment. The epidermis is thin and relatively atrophic with a flattened basement membrane and an almost total absence of epidermal crests. The dermis, with no clear distinction between a superficial and a deep zone, contain collagen fibers which are both thick and hyalizined (H&E 40x).

Tables

  • Table 1

    - Demographic data and histopathological results of the patients included in the current study.

    Patient’s no.ProductageLocalisationSurgical procedureHistology scar before procedureHistology scar after procedure
    1cicolea54Scar on rigt breastLatissmus dorsi flap expandendfibrous scar with chronic inflammationorganized scar process
    2cicolea47Scar on rigt breastfibrous scar with chronic inflammationscar process
    3cicolea61Scar on rigt breastfibrous scarorganized scar process
    4cicolea64bilateral breast scarfibrous scarorganized scar process
    5cicolea62left breast scarfibrous scarscar process
    6cicolea38rigt breast scarfibrous scarscar process
    7cicolea54left breast scarfibrous scarscar process
    8Petrolatum50Scar on rigt breastfibrous scarscar process
    9Petrolatum58left breast scarfibrous scar with granuloma processscar process
    10Petrolatum42left breast scarfibrous scarNon organized scar process
    11Petrolatum35left breast scarfibrous scarNon organized scar process
    12Petrolatum50Scar on rigt breastfibrous scarscar process
    13Petrolatum58left breast scarfibrous scar with cronic inflammationNon organized scar process
    14Petrolatum50Scar on rigt breastfibrous scarNon organized scar process
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