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NewsThe Cochrane Library Newsalert
Open Access

Cardiovascular disease risk in adults with compromised bone health

Saudi Medical Journal January 2023, 44 (1) 111;
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DECEMBER 05, 2022 - Adolescent and young adult (AYA) cancer survivors are at risk of experiencing treatment-related effects later in life, including damage to the heart. New research has identified various sociodemographic and modifiable risk factors associated with these patients’ risk of developing cardiovascular disease (CVD). The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

The study by investigators at Duke University and The University of Texas MD Anderson Cancer Center relied on 2009-2018 data from the National Health Interview Survey, which collects information on a broad range of health topics through personal interviews of US households. Responses from 4,766 AYA cancer survivors and 47,660 controls (without a history of cancer) were included.

The risk of CVD was significantly higher in survivors than controls by sex, race/ethnicity, income, education, smoking status, and physical activity. Also, household income <$50K/year disproportionately increased the odds of CVD in survivors compared with controls.

In the AYA survivor population, male sex, Black race, household income <$50K/year, and current or former smoking were all associated with higher odds of CVD. Performing any moderate to vigorous intensity physical activity was associated with lower CVD odds.

“These results highlight the importance of long-term surveillance of AYAs after cancer treatment to ensure that appropriate screenings are initiated to reduce the risk of CVD and to promote healthy behavioral changes, such as physical activity, which impact long-term CVD outcomes,” said lead author Amy Berkman, MD, of the Duke University School of Medicine.

Full Citation: “Cardiovascular disease in AYA cancer survivors: impact of sociodemographic and modifiable risk factors.” Amy M. Berkman, Clark R. Andersen, Michael E. Roth, and Susan C. Gilchrist. CANCER; Published Online: December 5, 2022 (DOI: 10.1002/cncr.34505).

URL Upon Publication: http://doi.wiley.com/10.1002/cncr.34505

Copyright © 2021 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd., reproduced with permission.

  • Copyright: © Saudi Medical Journal

This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Saudi Medical Journal: 44 (1)
Saudi Medical Journal
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1 Jan 2023
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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