Hughes’ antiphospholipid syndrome; 40 years on

Article Figures & Data

Table 1

- Other clinical manifestations of antiphospholipid syndrome.

Systems	Clinical features
Neurologic	Choreoathetosis, cognitive decline, migraine, myelitis, retinal ischemia, and seizures
Cardiovascular	Accelerated atherosclerosis, aortic and mitral valve thickening, cardiomyopathy, and non-infectious vegetations
Pulmonary	Diffuse alveolar haemorrhage, pulmonary hypertension
Renal	APS nephropathy, renal artery stenosis
Endocrine	Adrenal insufficiency
Haematologic	Autoimmune haemolytic anaemia, bleeding (due to hypothrombonemia), Evans syndrome, and thrombocytopenia
Articular	Arthralgia, arthritis, and avascular necrosis
Cutaneous	Digital ischemia, livedo racemosa/reticularis, livedoid vasculopathy, and splinter haemorrhages