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Research ArticleOriginal Article
Open Access

Effectiveness of generic sofosbuvir in the treatment of chronic hepatitis C virus infection in Saudi patients

Hamdan S. AlGhamdi, Ali A. AlHabobi, Rakan S. AlQahtani, Firas A. Ghomraoui, Khalefa M. AlThiab, Abdulrahman A. AlOun, Abduljaleel M. AlAlwan, Mutaz B. Abdelmahmoud, Ibrahim H. AlTraif and Abdulrahman A. Aljumah
Saudi Medical Journal December 2023, 44 (12) 1240-1247; DOI: https://doi.org/10.15537/smj.2023.44.12.20230481
Hamdan S. AlGhamdi
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Ali A. AlHabobi
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Rakan S. AlQahtani
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Firas A. Ghomraoui
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Khalefa M. AlThiab
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Abdulrahman A. AlOun
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Abduljaleel M. AlAlwan
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Mutaz B. Abdelmahmoud
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Ibrahim H. AlTraif
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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Abdulrahman A. Aljumah
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
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References

  1. 1.↵
    World Health Organization. The growing threats of hepatitis B and C in the Eastern Mediterranean Region: a call for action. [Udpated 2009; Accessed 2023 March 19] Available from: https://applications.emro.who.int/docs/EM_RC56_3_en.pdf
  2. 2.↵
    1. Aljumah AA,
    2. Kuriry H,
    3. Faisal N,
    4. Alghamdi H
    . Clinicopathologic characteristics and outcomes of hepatocellular carcinoma associated with chronic hepatitis B versus hepatitis C infection. Ann Saudi Med 2018; 38: 358–365.
    OpenUrl
  3. 3.↵
    1. Al MI,
    2. Abaalkhail FA,
    3. Bahili HA,
    4. Abdo AH,
    5. Elsiesy HA,
    6. Al MS, et al.
    Liver transplantation at KFSHRC: achievement and challenges. Ann Saudi Med 2014; 34: 103–106.
    OpenUrl
  4. 4.↵
    AASLD-IDSA. Recommendations for testing, managing, and treating hepatitis C. [Updated 2023: accessed 2023 May 20]. Available from: http://www.hcvguidelines.org
  5. 5.↵
    1. Sofia MJ,
    2. Bao D,
    3. Chang W,
    4. Du J,
    5. Nagarathnam D,
    6. Rachakonda S, et al.
    Discovery of a β-d-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine nucleotide prodrug (PSI-7977) for the treatment of hepatitis C virus. J Med Chem 2010; 53: 7202–7218.
    OpenUrlCrossRefPubMed
  6. 6.↵
    1. Gao M,
    2. Nettles RE,
    3. Belema M,
    4. Snyder LB,
    5. Nguyen VN,
    6. Fridell RA, et al.
    Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect. Nature 2010; 465: 96–100.
    OpenUrlCrossRefPubMedWeb of Science
  7. 7.↵
    1. Alghamdi AS,
    2. Alqutub A,
    3. Abaalkhail F,
    4. Sanai FM,
    5. Alghamdi H,
    6. Altraif I, et al.
    SASLT position statement on the direct-acting antiviral agents for the treatment of hepatitis C virus infection. Saudi J Gastroenterol 2015; 21: 60–63.
    OpenUrl
  8. 8.↵
    1. Cui F,
    2. Blach S,
    3. Manzengo Mingiedi C,
    4. Gonzalez MA,
    5. Sabry Alaama A,
    6. Mozalevskis A, et al.
    Global reporting of progress towards elimination of hepatitis B and hepatitis C. Lancet Gastroenterol Hepatol 2023; 8: 332–342.
    OpenUrl
  9. 9.↵
    1. Ward JW,
    2. Mermin JH
    . Simple, effective, but out of reach? public health implications of HCV drugs. N Engl J Med 2015; 3 73: 2678–2680.
    OpenUrl
  10. 10.↵
    World Health Organization. WHO moves to improve access to lifesaving medicines for hepatitis C, drug-resistant TB and cancers. [Updated 2015 May 8; Accessed 2023 March 19] Available from: https://www.who.int/news/item/08-05-2015-who-moves-to-improve-access-to-lifesaving-medicines-for-hepatitis-c-drug-resistant-tb-and-cancers
  11. 11.↵
    1. Elsharkawy A,
    2. El-Raziky M,
    3. El-Akel W,
    4. El-Saeed K,
    5. Eletreby R,
    6. Hassany M, et al.
    Planning and prioritizing direct-acting antivirals treatment for HCV patients in countries with limited resources: lessons from the Egyptian experience. J Hepatol 2018; 68: 691–698.
    OpenUrlCrossRefPubMed
  12. 12.↵
    1. Aljumah AA,
    2. Abaalkhail F,
    3. Al-Ashgar H,
    4. Assiri A,
    5. Babatin M,
    6. Al Faleh F, et al.
    Epidemiology, disease burden, and treatment strategies of chronic hepatitis C virus infections in Saudi Arabia in the new treatment paradigm shift. Saudi J Gastroenterol 2016; 22: 269–281.
    OpenUrl
  13. 13.↵
    European Association for the Study of the Liver. Electronic address: [email protected], Clinical Practice Guidelines Panel: Chair:, EASL Governing Board representative, Pawlotsky JM, Negro F, Aghemo A, et al. EASL recommendations on treatment of hepatitis C 2018. J Hepatol 2018; 69: 461–511.
    OpenUrlCrossRefPubMed
  14. 14.↵
    1. Sulkowski MS,
    2. Gardiner DF,
    3. Rodriguez-Torres M,
    4. Reddy KR,
    5. Hassanein T,
    6. Jacobson I, et al
    ; AI444040 Study Group. Daclatasvir plus sofosbuvir for previously treated or untreated chronic HCV infection. N Engl J Med 2014; 370: 211–221.
    OpenUrlCrossRefPubMedWeb of Science
  15. 15.↵
    1. Leroy V,
    2. Angus P,
    3. Bronowicki JP,
    4. Dore GJ,
    5. Hezode C,
    6. Pianko S, et al.
    Daclatasvir, sofosbuvir, and ribavirin for hepatitis C virus genotype 3 and advanced liver disease: A randomized phase III study (ALLY-3+). Hepatology 2016;63: 1430–1441.
    OpenUrlCrossRefPubMed
  16. 16.↵
    1. Perazzo H,
    2. Castro R,
    3. Luz PM,
    4. Banholi M,
    5. Goldenzon RV,
    6. Cardoso SW, et al.
    Effectiveness of generic direct-acting agents for the treatment of hepatitis C: systematic review and meta-analysis. Bull World Health Organ 2020; 98: 188–197K.
    OpenUrl
  17. 17.↵
    1. Al Traif I,
    2. Al Balwi MA,
    3. Abdulkarim I,
    4. Handoo FA,
    5. Alqhamdi HS,
    6. Alotaibi M, et al.
    HCV genotypes among 1013 Saudi nationals: a multicenter study. Ann Saudi Med 2013; 33: 10–12.
    OpenUrl
  18. 18.↵
    1. Joharji H,
    2. Alkortas D,
    3. Ajlan A,
    4. Ahmed M,
    5. Al-Ashgar H,
    6. Al-Quaiz M, et al.
    Efficacy of generic sofosbuvir with daclatasvir compared to sofosbuvir/ledipasvir in genotype 4 hepatitis C virus: A prospective comparison with historical control. Health Sci Rep 2022; 6: e980.
    OpenUrl
  19. 19.↵
    1. Kjellin M,
    2. Kileng H,
    3. Akaberi D,
    4. Palanisamy N,
    5. Duberg AS,
    6. Danielsson A, et al.
    Effect of the baseline Y93H resistance-associated substitution in HCV genotype 3 for direct-acting antiviral treatment: real-life experience from a multicenter study in Sweden and Norway. Scand J Gastroenterol 2019; 54: 1042–1050.
    OpenUrl
  20. 20.↵
    1. Nelson DR,
    2. Cooper JN,
    3. Lalezari JP,
    4. Lawitz E,
    5. Pockros PJ,
    6. Gitlin N, et al
    ; ALLY-3 Study Team. All-oral 12-week treatment with daclatasvir plus sofosbuvir in patients with hepatitis C virus genotype 3 infection: ALLY-3 phase III study. Hepatology. 2015 Apr;61(4):1127–35. https://doi.org/10.1002/hep.27726
    OpenUrlCrossRefPubMed
  21. 21.↵
    1. Wei L,
    2. Lim SG,
    3. Xie Q,
    4. Văn KN,
    5. Piratvisuth T,
    6. Huang Y, et al.
    Sofosbuvir-velpatasvir for treatment of chronic hepatitis C virus infection in Asia: a single-arm, open-label, phase 3 trial. Lancet Gastroenterol Hepatol 2019; 4: 127–134.
    OpenUrl
  22. 22.↵
    1. Butt N,
    2. Anoshia, Khan MA,
    3. Akbar A
    . Effectiveness of Sofosbuvir and Daclatasvir in treatment of Hepatitis-C: an experience of tertiary care hospital in Karachi. Pak J Med Sci 2021; 37: 2014–2019.
    OpenUrl
  23. 23.↵
    1. Mushtaq S,
    2. Mansoor A,
    3. Umar M,
    4. Khan A,
    5. Siddiqi S,
    6. Manzoor S
    . Direct-acting antiviral agents in the treatment of chronic hepatitis C-Real-life experience from clinical practices in Pakistan. J Med Virol 2020; 92: 3475–3487.
    OpenUrl
  24. 24.↵
    1. Zeuzem S,
    2. Foster GR,
    3. Wang S,
    4. Asatryan A,
    5. Gane E,
    6. Feld JJ, et al.
    Glecaprevir-Pibrentasvir for 8 or 12 Weeks in HCV Genotype 1 or 3 Infection. N Engl J Med 2018; 378: 354–369.
    OpenUrlCrossRefPubMed
  25. 25.
    1. Foster GR,
    2. Afdhal N,
    3. Roberts SK,
    4. Bräu N,
    5. Gane EJ,
    6. Pianko S, et al.
    ASTRAL-2 Investigators; ASTRAL-3 Investigators. Sofosbuvir and Velpatasvir for HCV Genotype 2 and 3 Infection. N Engl J Med 2015; 373: 2608–2617.
    OpenUrlCrossRefPubMed
  26. 26.
    1. Tasavon Gholamhoseini M,
    2. Sharafi H,
    3. Hl Borba H,
    4. Alavian SM,
    5. Sabermahani A,
    6. Hajarizadeh B
    . Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study. BMJ Open 2022; 12: e058757.
    OpenUrl
  27. 27.↵
    1. Soria A,
    2. Fava M,
    3. Bernasconi DP,
    4. Lapadula G,
    5. Colella E,
    6. Valsecchi MG, et al.
    Comparison of three therapeutic regimens for genotype-3 hepatitis C virus infection in a large real-life multicentre cohort. Liver Int 2020; 40: 769–777.
    OpenUrl
  28. 28.↵
    1. He S,
    2. Lockart I,
    3. Alavi M,
    4. Danta M,
    5. Hajarizadeh B,
    6. Dore GJ
    . Systematic review with meta-analysis: effectiveness of direct-acting antiviral treatment for hepatitis C in patients with hepatocellular carcinoma. Aliment Pharmacol Ther 2020; 51: 34–52.
    OpenUrl
  29. 29.↵
    1. Akbar DH,
    2. Siddique AM,
    3. Ahmed MM
    . Prevalence of Type-2 diabetes in patients with hepatitis C and B virus infection in Jeddah, Saudi Arabia. Med Princ Pract 2002; 11: 82–85.
    OpenUrlPubMed
  30. 30.↵
    1. Delgado-Borrego A,
    2. Jordan SH,
    3. Negre B,
    4. Healey D,
    5. Lin W,
    6. Kamegaya Y, et al
    ; Halt-C Trial Group. Reduction of insulin resistance with effective clearance of hepatitis C infection: results from the HALT-C trial. Clin Gastroenterol Hepatol 2010; 8: 458–462.
    OpenUrlCrossRefPubMedWeb of Science
  31. 31.↵
    1. Hum J,
    2. Jou JH,
    3. Green PK,
    4. Berry K,
    5. Lundblad J,
    6. Hettinger BD, et al.
    Improvement in glycemic control of type 2 diabetes after successful treatment of hepatitis C virus. Diabetes Care 2017; 40: 1173–1180.
    OpenUrlAbstract/FREE Full Text
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Effectiveness of generic sofosbuvir in the treatment of chronic hepatitis C virus infection in Saudi patients
Hamdan S. AlGhamdi, Ali A. AlHabobi, Rakan S. AlQahtani, Firas A. Ghomraoui, Khalefa M. AlThiab, Abdulrahman A. AlOun, Abduljaleel M. AlAlwan, Mutaz B. Abdelmahmoud, Ibrahim H. AlTraif, Abdulrahman A. Aljumah
Saudi Medical Journal Dec 2023, 44 (12) 1240-1247; DOI: 10.15537/smj.2023.44.12.20230481

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Effectiveness of generic sofosbuvir in the treatment of chronic hepatitis C virus infection in Saudi patients
Hamdan S. AlGhamdi, Ali A. AlHabobi, Rakan S. AlQahtani, Firas A. Ghomraoui, Khalefa M. AlThiab, Abdulrahman A. AlOun, Abduljaleel M. AlAlwan, Mutaz B. Abdelmahmoud, Ibrahim H. AlTraif, Abdulrahman A. Aljumah
Saudi Medical Journal Dec 2023, 44 (12) 1240-1247; DOI: 10.15537/smj.2023.44.12.20230481
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