Research ArticleOriginal Article
Open Access
Effectiveness of generic sofosbuvir in the treatment of chronic hepatitis C virus infection in Saudi patients
Hamdan S. AlGhamdi, Ali A. AlHabobi, Rakan S. AlQahtani, Firas A. Ghomraoui, Khalefa M. AlThiab, Abdulrahman A. AlOun, Abduljaleel M. AlAlwan, Mutaz B. Abdelmahmoud, Ibrahim H. AlTraif and Abdulrahman A. Aljumah
Saudi Medical Journal December 2023, 44 (12) 1240-1247; DOI: https://doi.org/10.15537/smj.2023.44.12.20230481
Hamdan S. AlGhamdi
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MBBS, MRCPAli A. AlHabobi
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MBBSRakan S. AlQahtani
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MBBSFiras A. Ghomraoui
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MBBSKhalefa M. AlThiab
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
PharmBAbdulrahman A. AlOun
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MBBSAbduljaleel M. AlAlwan
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MBBSMutaz B. Abdelmahmoud
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MBBS, MRCPIbrahim H. AlTraif
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MBBS, FRCPAbdulrahman A. Aljumah
From the Hepatobiliary Sciences & Organs Transplant Department (AlGhamdi, AlAlwan, Alqahtani, Aloun, Abdelmahmoud, ATtraif), Hepatology Section and From the Department of Internal Medicine (AlHabobi), King Abdulaziz Medical City of National Guard; from King Saud Bin Abdulaziz University for health sciences (AlGhamdi, AlAlwan, AlThiab); from King Abdullah International Research Centre (AlGhamdi, AlAlwan, AlThiab), Ministry of National Guard Health Affairs; From the Department of Pharmaceutical Care Services (AlThiab), King Abdulaziz Medical City of National Guard; Form the College of Medicine (AlJumah), Dar Al-Uloom University, Riyadh, Kingdom of Saudi Arabia; and From the Department of Internal Medicine (Ghomraoui), Sisters of Charity Hospital, Buffalo, New York, United States of America.
MD, FRCP (I)References
- 1.↵World Health Organization. The growing threats of hepatitis B and C in the Eastern Mediterranean Region: a call for action. [Udpated 2009; Accessed 2023 March 19] Available from: https://applications.emro.who.int/docs/EM_RC56_3_en.pdf
- 2.↵
- Aljumah AA,
- Kuriry H,
- Faisal N,
- Alghamdi H
- 3.↵
- Al MI,
- Abaalkhail FA,
- Bahili HA,
- Abdo AH,
- Elsiesy HA,
- Al MS, et al.
- 4.↵AASLD-IDSA. Recommendations for testing, managing, and treating hepatitis C. [Updated 2023: accessed 2023 May 20]. Available from: http://www.hcvguidelines.org
- 5.↵
- 6.↵
- Gao M,
- Nettles RE,
- Belema M,
- Snyder LB,
- Nguyen VN,
- Fridell RA, et al.
- 7.↵
- Alghamdi AS,
- Alqutub A,
- Abaalkhail F,
- Sanai FM,
- Alghamdi H,
- Altraif I, et al.
- 8.↵
- Cui F,
- Blach S,
- Manzengo Mingiedi C,
- Gonzalez MA,
- Sabry Alaama A,
- Mozalevskis A, et al.
- 9.↵
- Ward JW,
- Mermin JH
- 10.↵World Health Organization. WHO moves to improve access to lifesaving medicines for hepatitis C, drug-resistant TB and cancers. [Updated 2015 May 8; Accessed 2023 March 19] Available from: https://www.who.int/news/item/08-05-2015-who-moves-to-improve-access-to-lifesaving-medicines-for-hepatitis-c-drug-resistant-tb-and-cancers
- 11.↵
- 12.↵
- Aljumah AA,
- Abaalkhail F,
- Al-Ashgar H,
- Assiri A,
- Babatin M,
- Al Faleh F, et al.
- 13.↵European Association for the Study of the Liver. Electronic address: [email protected], Clinical Practice Guidelines Panel: Chair:, EASL Governing Board representative, Pawlotsky JM, Negro F, Aghemo A, et al. EASL recommendations on treatment of hepatitis C 2018. J Hepatol 2018; 69: 461–511.
- 14.↵
- Sulkowski MS,
- Gardiner DF,
- Rodriguez-Torres M,
- Reddy KR,
- Hassanein T,
- Jacobson I, et al
- 15.↵
- 16.↵
- Perazzo H,
- Castro R,
- Luz PM,
- Banholi M,
- Goldenzon RV,
- Cardoso SW, et al.
- 17.↵
- Al Traif I,
- Al Balwi MA,
- Abdulkarim I,
- Handoo FA,
- Alqhamdi HS,
- Alotaibi M, et al.
- 18.↵
- Joharji H,
- Alkortas D,
- Ajlan A,
- Ahmed M,
- Al-Ashgar H,
- Al-Quaiz M, et al.
- 19.↵
- Kjellin M,
- Kileng H,
- Akaberi D,
- Palanisamy N,
- Duberg AS,
- Danielsson A, et al.
- 20.↵
- Nelson DR,
- Cooper JN,
- Lalezari JP,
- Lawitz E,
- Pockros PJ,
- Gitlin N, et al
- 21.↵
- Wei L,
- Lim SG,
- Xie Q,
- Văn KN,
- Piratvisuth T,
- Huang Y, et al.
- 22.↵
- Butt N,
- Anoshia, Khan MA,
- Akbar A
- 23.↵
- Mushtaq S,
- Mansoor A,
- Umar M,
- Khan A,
- Siddiqi S,
- Manzoor S
- 24.↵
- 25.
- 26.
- Tasavon Gholamhoseini M,
- Sharafi H,
- Hl Borba H,
- Alavian SM,
- Sabermahani A,
- Hajarizadeh B
- 27.↵
- Soria A,
- Fava M,
- Bernasconi DP,
- Lapadula G,
- Colella E,
- Valsecchi MG, et al.
- 28.↵
- He S,
- Lockart I,
- Alavi M,
- Danta M,
- Hajarizadeh B,
- Dore GJ
- 29.↵
- 30.↵
- Delgado-Borrego A,
- Jordan SH,
- Negre B,
- Healey D,
- Lin W,
- Kamegaya Y, et al
- 31.↵
- Hum J,
- Jou JH,
- Green PK,
- Berry K,
- Lundblad J,
- Hettinger BD, et al.
In this issue
Effectiveness of generic sofosbuvir in the treatment of chronic hepatitis C virus infection in Saudi patients
Hamdan S. AlGhamdi, Ali A. AlHabobi, Rakan S. AlQahtani, Firas A. Ghomraoui, Khalefa M. AlThiab, Abdulrahman A. AlOun, Abduljaleel M. AlAlwan, Mutaz B. Abdelmahmoud, Ibrahim H. AlTraif, Abdulrahman A. Aljumah
Saudi Medical Journal Dec 2023, 44 (12) 1240-1247; DOI: 10.15537/smj.2023.44.12.20230481
Effectiveness of generic sofosbuvir in the treatment of chronic hepatitis C virus infection in Saudi patients
Hamdan S. AlGhamdi, Ali A. AlHabobi, Rakan S. AlQahtani, Firas A. Ghomraoui, Khalefa M. AlThiab, Abdulrahman A. AlOun, Abduljaleel M. AlAlwan, Mutaz B. Abdelmahmoud, Ibrahim H. AlTraif, Abdulrahman A. Aljumah
Saudi Medical Journal Dec 2023, 44 (12) 1240-1247; DOI: 10.15537/smj.2023.44.12.20230481
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