Assessing the adverse effects of COVID-19 vaccine in different scenarios in Saudi Arabia: A cross-sectional study

Ahad Amer Alsaiari; Mamdouh Allahyani; Abdulelah Aljuaid; Alaa Shafie; Ayman Al-hazmi; Haytham A. Dahlawi; Osama Abdulaziz; Ebtisam Alosimi; Albatool Alzaidi; Mazen Almehmadi

doi:10.15537/smj.2023.44.2.20220680

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2. Alhazmi A,
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4. Alamer R,
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6. Gohal G,et al.
Side Effects of COVID-19 Pfizer-BioNTech vaccine in children aged 12-18 years in Saudi Arabia. Vaccines (Basel) 2021; 9: 1512739.
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2. Ibrahim A,
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4. Joseph M,
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A cross-sectional survey of side effects after COVID-19 vaccination in Saudi Arabia: male versus female outcomes. J Adv Pharm Educ Res 2021; 11: 51–56.
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1. Alharbi NK,
2. Al-Tawfiq JA,
3. Alghnam S,
4. Alwehaibe A,
5. Alasmari A,
6. Alsagaby SA, et al.
Outcomes of single dose COVID-19 vaccines: Eight month follow-up of a large cohort in Saudi Arabia. J Infect Public Health 2022; 15: 573–577.
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1. Alhazmi A,
2. Alamer E,
3. Daws D,
4. Hakami M,
5. Darraj M,
6. Abdelwahab S, et al.
Evaluation of side effects associated with COVID-19 vaccines in Saudi Arabia. Vaccines 2021; 9: 674.
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1. Al-Hanawi MK,
2. Keetile M,
3. Kadasah NA,
4. Alshareef N,
5. Qattan AMN,
6. Alsharqi O.
Side effects and perceptions of COVID-19 vaccination in Saudi Arabia: A cross-sectional study. Front Med (Lausanne) 2022; 9: 899517.
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1. Alhowaymel F,
2. Abdelmalik MA,
3. Mohammed AM.
Reported side effects of COVID-19 vaccination among adults in Saudi Arabia: A cross-sectional study. SAGE Open Nurs 2022; 8: 1–9.
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7.↵
1. Almughais ES,
2. Alharbi AH,
3. Aldarwish HA,
4. Alshammari AF,
5. Alsuhaymi RS,
6. Almuaili JA, et al.
Side-effects of COVID-19 vaccines among the Saudi population: A cross-sectional study. Saudi Med J 2022; 43: 386–393.
OpenUrl Abstract/FREE Full Text
8.↵
1. Alzarea AI,
2. Khan YH,
3. Alatawi AD,
4. Alanazi AS,
5. Alzarea SI,
6. Butt MH, et al.
Surveillance of post-vaccination side effects of COVID-19 vaccines among Saudi Population: A real-world estimation of safety profile. Vaccines 2022; 10: 924.
OpenUrl
9.↵
1. Andrzejczak-Grządko S,
2. Czudy Z,
3. Donderska M.
Side effects after COVID-19 vaccinations among residents of Poland. Eur Rev Med Pharm Sci 2021; 25: 4418–4421.
OpenUrl
10.↵
1. Bukhari AE,
2. Almutlq MM,
3. Bin Dakhil AA,
4. Alhetheli GI,
5. Alfouzan SK,
6. Alqahtani MA, et al.
Cutaneous adverse reactions to coronavirus vaccines: A Saudi nationwide study. Dermatol Ther 2022; 35: e15452.
OpenUrl
11.↵
1. Dar-Odeh N,
2. Abu-Hammad O,
3. Qasem F,
4. Alhodhodi A,
5. Othman A,
6. Abu-Hammad A, et al.
Long-term adverse events of three COVID-19 vaccines as reported by vaccinated physicians and dentists; A study from Jordan and Saudi Arabia. Hum Vaccines Immunother 2022; 18: 2039017.
OpenUrl
12.↵
1. Elgendy MO,
2. El-Gendy AO,
3. Abdelrahim ME.
Public awareness in Egypt about COVID-19 spread in the early phase of the pandemic. Patient Educ Couns 2020; 103: 2598–2601.
OpenUrl
13.↵
1. Elgendy MO,
2. Elmawla MNA,
3. Hamied AMA,
4. El Gendy SO,
5. Abdelrahim MEA.
COVID-19 patients and contacted person awareness about home quarantine instructions. Int J Clin Pract 2021; 75: e13810.
OpenUrl
14.↵
1. Lupu L,
2. Palmer A,
3. Huber-Lang M.
Inflammation, thrombosis, and destruction: The three-headed cerberus of trauma- and SARS-CoV-2-induced ARDS. Front Immunol 2020; 11: 584514.
OpenUrl
15.
1. Ibrahim F,
2. Alzayyat R,
3. Alzayyat N,
4. Alomran S,
5. Wafai S,
6. Alabssi H, et al.
Side Effects of COVID-19 Vaccines (Pfizer, AstraZeneca) in Saudi Arabia, Eastern Province. Cureus 2022; 14: e27297.
OpenUrl
16.
1. Kar SK,
2. Saxena SK,
3. Kabir R.
The relevance of digital mental healthcare during COVID-19: Need for innovations. Nepal J. Epidemiol 2020; 10: 928–929.
OpenUrl
17.↵
1. Klugar M,
2. Riad A,
3. Mekhemar M,
4. Conrad J,
5. Buchbender M,
6. Howaldt HP, et al.
Side effects of mRNA-based and viral vector-based COVID-19 vaccines among German healthcare workers. Biology 2021; 10: 752.
OpenUrl
18.↵
1. Mehboob R,
2. Ahmad JF,
3. Qayyum A,
4. Rana AM,
5. Gilani AS,
6. Tariq AM, et al.
Aprepitant as a combinant with Dexamethasone reduces the inflammation via Neurokinin 1 Receptor Antagonism in severe to critical COVID-19 patients and potentiates respiratory recovery: A novel therapeutic approach. medRxiv 2020.
19.
1. Noda K,
2. Matsuda K,
3. Yagishita S,
4. Maeda K,
5. Akiyama Y,
6. Hirashima-Terada J, et al.
A novel highly quantitative and reproducible assay for the detection of anti-SARS-CoV-2 IgG and IgM antibodies. Sci Rep 2021; 11: 1–10.
OpenUrl CrossRef PubMed
20.↵
1. Othman SS,
2. Alsuwaidi A,
3. Aseel R,
4. Alotaibi R,
5. Bablgoom R,
6. Alsulami G, et al.
Association between social media use and the acceptance of COVID-19 vaccination among the general population in Saudi Arabia – A cross-sectional study. BMC Public Health 2022; 22: 375.
OpenUrl
21.↵
1. Riad A,
2. Sağıroğlu D,
3. Üstün B,
4. Pokorná A,
5. Klugarová J,
6. Attia S,
7. Klugar M.
Prevalence and risk factors of CoronaVac side effects: An independent cross-sectional study among healthcare workers in Turkey. J Clin Med 2021; 10: 2629.
OpenUrl
22.
1. Solomon, Y.;
2. Eshete, T.;
3. Mekasha, B.;
4. Assefa, W.
COVID-19 vaccine: side effects after the first dose of the Oxford AstraZeneca vaccine among health professionals in low-income country: Ethiopia J Multidiscip Healthc 2021; 14: 2577.
OpenUrl
23.↵
1. Tripathy, S.;
2. Kabir, R.;
3. Arafat, S.Y.;
4. Saxena, S.K.
Futuristic Technologies for advanced detection, prevention, and control of COVID-19. Diagnostic strategies for COVID-19 and other Coronaviruses; Springer: Singapore, 2020; pp. 161–173.

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Keywords

[1] 1.↵
Alamer E,
Alhazmi A,
Qasir NA,
Alamer R,
Areeshi H,
Gohal G,et al.
Side Effects of COVID-19 Pfizer-BioNTech vaccine in children aged 12-18 years in Saudi Arabia. Vaccines (Basel) 2021; 9: 1512739.
OpenUrl

[2] Alamer E,

[3] Alhazmi A,

[4] Qasir NA,

[5] Alamer R,

[6] Areeshi H,

[7] Gohal G,et al.

[8] 2.
Alghamdi A,
Ibrahim A,
Almutairi R,
Joseph M,
Alghamdi G,
Alhamza A.
A cross-sectional survey of side effects after COVID-19 vaccination in Saudi Arabia: male versus female outcomes. J Adv Pharm Educ Res 2021; 11: 51–56.
OpenUrl

[9] Alghamdi A,

[10] Ibrahim A,

[11] Almutairi R,

[12] Joseph M,

[13] Alghamdi G,

[14] Alhamza A.

[15] 3.↵
Alharbi NK,
Al-Tawfiq JA,
Alghnam S,
Alwehaibe A,
Alasmari A,
Alsagaby SA, et al.
Outcomes of single dose COVID-19 vaccines: Eight month follow-up of a large cohort in Saudi Arabia. J Infect Public Health 2022; 15: 573–577.
OpenUrl

[16] Alharbi NK,

[17] Al-Tawfiq JA,

[18] Alghnam S,

[19] Alwehaibe A,

[20] Alasmari A,

[21] Alsagaby SA, et al.

[22] 4.↵
Alhazmi A,
Alamer E,
Daws D,
Hakami M,
Darraj M,
Abdelwahab S, et al.
Evaluation of side effects associated with COVID-19 vaccines in Saudi Arabia. Vaccines 2021; 9: 674.
OpenUrl

[23] Alhazmi A,

[24] Alamer E,

[25] Daws D,

[26] Hakami M,

[27] Darraj M,

[28] Abdelwahab S, et al.

[29] 5.
Al-Hanawi MK,
Keetile M,
Kadasah NA,
Alshareef N,
Qattan AMN,
Alsharqi O.
Side effects and perceptions of COVID-19 vaccination in Saudi Arabia: A cross-sectional study. Front Med (Lausanne) 2022; 9: 899517.
OpenUrl

[30] Al-Hanawi MK,

[31] Keetile M,

[32] Kadasah NA,

[33] Alshareef N,

[34] Qattan AMN,

[35] Alsharqi O.

[36] 6.↵
Alhowaymel F,
Abdelmalik MA,
Mohammed AM.
Reported side effects of COVID-19 vaccination among adults in Saudi Arabia: A cross-sectional study. SAGE Open Nurs 2022; 8: 1–9.
OpenUrl

[37] Alhowaymel F,

[38] Abdelmalik MA,

[39] Mohammed AM.

[40] 7.↵
Almughais ES,
Alharbi AH,
Aldarwish HA,
Alshammari AF,
Alsuhaymi RS,
Almuaili JA, et al.
Side-effects of COVID-19 vaccines among the Saudi population: A cross-sectional study. Saudi Med J 2022; 43: 386–393.
OpenUrl Abstract/FREE Full Text

[41] Almughais ES,

[42] Alharbi AH,

[43] Aldarwish HA,

[44] Alshammari AF,

[45] Alsuhaymi RS,

[46] Almuaili JA, et al.

[47] 8.↵
Alzarea AI,
Khan YH,
Alatawi AD,
Alanazi AS,
Alzarea SI,
Butt MH, et al.
Surveillance of post-vaccination side effects of COVID-19 vaccines among Saudi Population: A real-world estimation of safety profile. Vaccines 2022; 10: 924.
OpenUrl

[48] Alzarea AI,

[49] Khan YH,

[50] Alatawi AD,

[51] Alanazi AS,

[52] Alzarea SI,

[53] Butt MH, et al.

[54] 9.↵
Andrzejczak-Grządko S,
Czudy Z,
Donderska M.
Side effects after COVID-19 vaccinations among residents of Poland. Eur Rev Med Pharm Sci 2021; 25: 4418–4421.
OpenUrl

[55] Andrzejczak-Grządko S,

[56] Czudy Z,

[57] Donderska M.

[58] 10.↵
Bukhari AE,
Almutlq MM,
Bin Dakhil AA,
Alhetheli GI,
Alfouzan SK,
Alqahtani MA, et al.
Cutaneous adverse reactions to coronavirus vaccines: A Saudi nationwide study. Dermatol Ther 2022; 35: e15452.
OpenUrl

[59] Bukhari AE,

[60] Almutlq MM,

[61] Bin Dakhil AA,

[62] Alhetheli GI,

[63] Alfouzan SK,

[64] Alqahtani MA, et al.

[65] 11.↵
Dar-Odeh N,
Abu-Hammad O,
Qasem F,
Alhodhodi A,
Othman A,
Abu-Hammad A, et al.
Long-term adverse events of three COVID-19 vaccines as reported by vaccinated physicians and dentists; A study from Jordan and Saudi Arabia. Hum Vaccines Immunother 2022; 18: 2039017.
OpenUrl

[66] Dar-Odeh N,

[67] Abu-Hammad O,

[68] Qasem F,

[69] Alhodhodi A,

[70] Othman A,

[71] Abu-Hammad A, et al.

[72] 12.↵
Elgendy MO,
El-Gendy AO,
Abdelrahim ME.
Public awareness in Egypt about COVID-19 spread in the early phase of the pandemic. Patient Educ Couns 2020; 103: 2598–2601.
OpenUrl

[73] Elgendy MO,

[74] El-Gendy AO,

[75] Abdelrahim ME.

[76] 13.↵
Elgendy MO,
Elmawla MNA,
Hamied AMA,
El Gendy SO,
Abdelrahim MEA.
COVID-19 patients and contacted person awareness about home quarantine instructions. Int J Clin Pract 2021; 75: e13810.
OpenUrl

[77] Elgendy MO,

[78] Elmawla MNA,

[79] Hamied AMA,

[80] El Gendy SO,

[81] Abdelrahim MEA.

[82] 14.↵
Lupu L,
Palmer A,
Huber-Lang M.
Inflammation, thrombosis, and destruction: The three-headed cerberus of trauma- and SARS-CoV-2-induced ARDS. Front Immunol 2020; 11: 584514.
OpenUrl

[83] Lupu L,

[84] Palmer A,

[85] Huber-Lang M.

[86] 15.
Ibrahim F,
Alzayyat R,
Alzayyat N,
Alomran S,
Wafai S,
Alabssi H, et al.
Side Effects of COVID-19 Vaccines (Pfizer, AstraZeneca) in Saudi Arabia, Eastern Province. Cureus 2022; 14: e27297.
OpenUrl

[87] Ibrahim F,

[88] Alzayyat R,

[89] Alzayyat N,

[90] Alomran S,

[91] Wafai S,

[92] Alabssi H, et al.

[93] 16.
Kar SK,
Saxena SK,
Kabir R.
The relevance of digital mental healthcare during COVID-19: Need for innovations. Nepal J. Epidemiol 2020; 10: 928–929.
OpenUrl

[94] Kar SK,

[95] Saxena SK,

[96] Kabir R.

[97] 17.↵
Klugar M,
Riad A,
Mekhemar M,
Conrad J,
Buchbender M,
Howaldt HP, et al.
Side effects of mRNA-based and viral vector-based COVID-19 vaccines among German healthcare workers. Biology 2021; 10: 752.
OpenUrl

[98] Klugar M,

[99] Riad A,

[100] Mekhemar M,

[101] Conrad J,

[102] Buchbender M,

[103] Howaldt HP, et al.

[104] 18.↵
Mehboob R,
Ahmad JF,
Qayyum A,
Rana AM,
Gilani AS,
Tariq AM, et al.
Aprepitant as a combinant with Dexamethasone reduces the inflammation via Neurokinin 1 Receptor Antagonism in severe to critical COVID-19 patients and potentiates respiratory recovery: A novel therapeutic approach. medRxiv 2020.

[105] Mehboob R,

[106] Ahmad JF,

[107] Qayyum A,

[108] Rana AM,

[109] Gilani AS,

[110] Tariq AM, et al.

[111] 19.
Noda K,
Matsuda K,
Yagishita S,
Maeda K,
Akiyama Y,
Hirashima-Terada J, et al.
A novel highly quantitative and reproducible assay for the detection of anti-SARS-CoV-2 IgG and IgM antibodies. Sci Rep 2021; 11: 1–10.
OpenUrl CrossRef PubMed

[112] Noda K,

[113] Matsuda K,

[114] Yagishita S,

[115] Maeda K,

[116] Akiyama Y,

[117] Hirashima-Terada J, et al.

[118] 20.↵
Othman SS,
Alsuwaidi A,
Aseel R,
Alotaibi R,
Bablgoom R,
Alsulami G, et al.
Association between social media use and the acceptance of COVID-19 vaccination among the general population in Saudi Arabia – A cross-sectional study. BMC Public Health 2022; 22: 375.
OpenUrl

[119] Othman SS,

[120] Alsuwaidi A,

[121] Aseel R,

[122] Alotaibi R,

[123] Bablgoom R,

[124] Alsulami G, et al.

[125] 21.↵
Riad A,
Sağıroğlu D,
Üstün B,
Pokorná A,
Klugarová J,
Attia S,
Klugar M.
Prevalence and risk factors of CoronaVac side effects: An independent cross-sectional study among healthcare workers in Turkey. J Clin Med 2021; 10: 2629.
OpenUrl

[126] Riad A,

[127] Sağıroğlu D,

[128] Üstün B,

[129] Pokorná A,

[130] Klugarová J,

[131] Attia S,

[132] Klugar M.

[133] 22.
Solomon, Y.;
Eshete, T.;
Mekasha, B.;
Assefa, W.
COVID-19 vaccine: side effects after the first dose of the Oxford AstraZeneca vaccine among health professionals in low-income country: Ethiopia J Multidiscip Healthc 2021; 14: 2577.
OpenUrl

[134] Solomon, Y.;

[135] Eshete, T.;

[136] Mekasha, B.;

[137] Assefa, W.

[138] 23.↵
Tripathy, S.;
Kabir, R.;
Arafat, S.Y.;
Saxena, S.K.
Futuristic Technologies for advanced detection, prevention, and control of COVID-19. Diagnostic strategies for COVID-19 and other Coronaviruses; Springer: Singapore, 2020; pp. 161–173.

[139] Tripathy, S.;

[140] Kabir, R.;

[141] Arafat, S.Y.;

[142] Saxena, S.K.

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Assessing the adverse effects of COVID-19 vaccine in different scenarios in Saudi Arabia

A cross-sectional study

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Assessing the adverse effects of COVID-19 vaccine in different scenarios in Saudi Arabia

A cross-sectional study

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