Article Figures & Data
Tables
- Table 1
-Comparison of the demographic variables between type 2 diabetes mellitus patients and healthy control group.
Variables T2DM (n=271) Control (n=275) P-values Gender (male/female) 128/143 124/151 0.616 Age (years) 56.2±11.9 55.8±13.6 0.512 Weight (kg) 74.4±12.9 70.6±12.6 <0.0001 Height (cm) 161.8±8.6 163.3±7.3 0.015 BMI (kg/m2) 28.4±4.6 26.6±4.9 <0.0001 FPG (mmol/L) 13.4±5.6 5.7±1.0 <0.0001 HbA1c (%) 8.9±1.6 5.8±0.8 <0.0001 Values are presented as means ± standard deviations (SD). T2DM: type 2 diabetes mellitus, BMI: body mass index, FPG: fasting plasma glucose, HbA1c: glycosylated hemoglobin
- Table 2
-Allele change (frequency) of the nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 rs35829419 single-nucleotide polymorphism among type 2 diabetes mellitus and control group.
SNP Total (n=546) T2DM (n=271) Control (n=275) HWE’s P-value OR (95% CI) P-values* CC 494 (90.5) 237 (87.4) 257 (93.5) 0.575 1.00 - CA 51 (9.3) 33 (12.2) 18 (6.5) 1.99 (1.11-3.61) 0.027 AA 1 (0.2) 1 (0.4) 0 (0.0) NA NA CA+AA 52 (9.5) 34 (12.5) 18 (6.5) 2.05 (1.16-3.75) 0.019 C 1039 (95.1) 507 (93.5) 532 (96.7) 1.00 - A 53 (4.9) 35 (6.5) 18 (3.3) 2.04 (1.15-3.70) 0.016 ↵Values are presented as numbers and precentages (%). *Fisher exact test. SNP: single-nucleotide polymorphism, T2DM: type 2 diabetes mellitus, HWE: Hardy-Weinberg equilibrium, OR: odds ratio, CI: confidence interval, NA: not available
- Table 3
-Basic characteristics of studied groups by nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 rs35829419 genotype.
Variables T2DM Control CC CA P-values CC CA P-values Age (years) 56.4±11.6 59.2±13.9 0.192 56.2±13.9 54.7±9.6 0.329 Weight (kg) 73.5±11.8 78.2±9.9 0.032 70.6±11.1 66.9±15.6 0.188 Height (cm) 161.9±8.4 162.5±7.7 0.711 163.5±7.0 162.9±10.3 0.874 BMI (kg/m2) 28.1±4.2 29.7±4.2 0.031 26.8±4.3 26.0±4.3 0.677 FPG (mmol/L) 11.9±4.7 10.9±3.9 0.287 5.7±1.0 5.7±0.8 0.977 HbA1c (%) 8.9±1.8 8.5±1.4 0.179 5.9±0.5 5.3±0.4 0.191 Values are presented as means ± standard deviations (SD). T2DM: type 2 diabetes mellitus, BMI: body mass index, FPG: fasting plasma glucose, HbA1c: glycated hemoglobin