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NewsThe Cochrane Library Newsalert
Open Access

Could Botox make walking easier in children with cerebral palsy?

Saudi Medical Journal September 2024, 45 (9) 1000;
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JULY 24, 2024 - A recent randomized clinical trial published in Developmental Medicine & Child Neurology assessed whether injections of botulinumtoxin-A in calf muscles benefit children with cerebral palsy.

“We hypothesized that injections with botulinumtoxin-A in the calf muscles would make walking easier, caused by improved ankle joint functioning following spasticity reduction,” the authors wrote.

In the trial, one botulinumtoxin-A treatment was not superior to placebo in making walking easier (measured as a reduction in energy cost or improved walking capacity); however, there was some evidence of a delayed improvement in energy cost. Moreover, there was some evidence of a decrease in calf pain intensity. No serious adverse events related to botulinumtoxin-A treatment were recorded.

URL upon publication: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16038

Full citation: “Does botulinum neurotoxin A make walking easier in children with cerebral palsy? A randomized clinical trial.” Siri Merete Brændvik, Anne Elisabeth Ross Raftemo, Karin Roeleveld, Guro Lillemoen Andersen, Kjersti Ramstad, Turid Follestad, Ånen Aarli, Marcin Bonikowski, Torstein Vik, Walking Easier. Dev Med Child Neurol; Published Online: 12 June 2024 (DOI: 10.1111/dmcn.16038).

Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd., Reproduced with permission.

  • Copyright: © Saudi Medical Journal

This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Saudi Medical Journal: 45 (9)
Saudi Medical Journal
Vol. 45, Issue 9
1 Sep 2024
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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