Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
NewsThe Cochrane Library Newsalert
Open Access

Does obesity affect children’s likelihood of survival after being diagnosed with cancer?

Saudi Medical Journal February 2025, 46 (2) 204-205;
  • Article
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

JANUARY 13, 2025 - A recent population-based study indicates that among children with cancer, those with obesity at the time of diagnosis may face an elevated risk of dying. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

The retrospective study was based on information from the Cancer in Young People in Canada (CYP-C) database, including all children with newly diagnosed cancer aged 2 to 18 years across Canada from 2001 to 2020. Obesity was defined as age and sex-adjusted body mass index at or above the 95th percentile.

Among 11,291 children with cancer, 10.5% were obese at the time of diagnosis. Investigators assessed 5-year event-free survival (survival free of cancer relapse), as well as overall survival.

Compared with patients without obesity at the time of initial cancer diagnosis, those with obesity had lower rates of 5-year event-free survival (77.5% versus 79.6%) and overall survival (83.0% versus 85.9%).

After adjusting for factors including age, sex, ethnicity, neighborhood income quintile, treatment era, and cancer categories, obesity at diagnosis was linked with a 16% increase in the risk of relapse and a 29% increase in the risk of death. The negative impact of obesity on prognosis was especially pronounced in patients with acute lymphoblastic leukemia and brain tumors.

“Our study highlights the negative impact of obesity among all types of childhood cancers. It provides the rationale to evaluate different strategies to mitigate the adverse risk of obesity on cancer outcomes in future trials,” said co–senior author Thai Hoa Tran, MD, of the Centre Hospitalier Universitaire Sainte-Justine, in Montreal. “It also reinforces the urgent need to reduce the epidemic of childhood obesity as it can result in significant health consequences.”

URL upon publication: http://doi.wiley.com/10.1002/cncr.35673

Full citation: ““Impact of Obesity on Outcome in Children Diagnosed with Cancer in Canada: A Report from CYP-C.” Samuel Sassine, André P. Ilinca, Hallie Coltin, Henrique Bittencourt, Uma Athale, Lynette Bowes, Josée Brossard, Sara Israels, Donna L. Johnston, Ketan Kulkarni, Sarah McKillop, Meera Rayar, Roona Sinha, Tony Truong, Catherine Vézina, Laura Wheaton, Alexandra P. Zorzi, Lillian Sung, Marie-Claude Pelland-Marcotte, and Thai Hoa Tran. CANCER; Published Online: January 13, 2025 (DOI: 10.1002/cncr.35673).

Copyright © 2019 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd., Reproduced with permission.

  • Copyright: © Saudi Medical Journal

This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

PreviousNext
Back to top

In this issue

Saudi Medical Journal: 46 (2)
Saudi Medical Journal
Vol. 46, Issue 2
1 Feb 2025
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Does obesity affect children’s likelihood of survival after being diagnosed with cancer?
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
Does obesity affect children’s likelihood of survival after being diagnosed with cancer?
Saudi Medical Journal Feb 2025, 46 (2) 204-205;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Does obesity affect children’s likelihood of survival after being diagnosed with cancer?
Saudi Medical Journal Feb 2025, 46 (2) 204-205;
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Does cancer treatment affect connections in the brain?
  • Do disasters delay early cancer diagnoses?
  • Do lifetime body weight patterns affect kidney cancer risk?
Show more The Cochrane Library Newsalert

Similar Articles

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire