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Review ArticleReview Article
Open Access

Management of Crigler-Najjar Syndrome type I

Haider A. Al-Shurafa, Atef F. Bassas, Dieter C. Broering, Xavier G. Rogiers, Sami H. Wali and Martin M. Burdelski
Saudi Medical Journal June 2001, 22 (6) 486-489;
Haider A. Al-Shurafa
Department of Hepatobiliary Surgery and Transplantation, University Hospital Hamburg-Eppendorf, Martini Street 52, 20246 Hamburg, Germany. Tel. +49 (40) 42803 6135/6136. Fax. +49 (40) 42803 3431. Email:[email protected]
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Atef F. Bassas
Riyadh Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia.
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Dieter C. Broering
Department of Hepatobiliary Surgery and Transplantation, University Hospital Hamburg-Eppendorf, Germany
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Xavier G. Rogiers
Department of Hepatobiliary Surgery and Transplantation, University Hospital Hamburg-Eppendorf, Germany
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Sami H. Wali
Riyadh Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia.
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Martin M. Burdelski
Department of Hepatobiliary Surgery and Transplantation, University Hospital Hamburg-Eppendorf, Germany
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Abstract

Crigler-Najjar Syndrome type I is a rare congenital disease with high mortality and morbidity rates due to brain complications. It has been treated by life-long phototherapy until the era of liver transplantation. Liver transplantation is currently the only curative treatment for this syndrome. Liver transplantation prevents the severe neurological complications that are the main cause of life-long disability in Crigler-Najjar Syndrome type I. The ideal age for transplantation is 3-5 years. Despite the advent of auxiliary transplantation we believe that orthotopic liver transplantation is the optimal treatment and the ideal method of liver transplantation for Crigler-Najjar Syndrome type I.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 22 (6)
Saudi Medical Journal
Vol. 22, Issue 6
1 Jun 2001
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Management of Crigler-Najjar Syndrome type I
Haider A. Al-Shurafa, Atef F. Bassas, Dieter C. Broering, Xavier G. Rogiers, Sami H. Wali, Martin M. Burdelski
Saudi Medical Journal Jun 2001, 22 (6) 486-489;

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Management of Crigler-Najjar Syndrome type I
Haider A. Al-Shurafa, Atef F. Bassas, Dieter C. Broering, Xavier G. Rogiers, Sami H. Wali, Martin M. Burdelski
Saudi Medical Journal Jun 2001, 22 (6) 486-489;
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© 2023 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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