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Research ArticleOriginal Article
Open Access

Hope for clomiphene citrate resistant ovaries

Mahmoud N. Abdul Salam, Fathia H. Hasanain and Bothina K. Greiew
Saudi Medical Journal June 2001, 22 (6) 508-511;
Mahmoud N. Abdul Salam
Department of Obstetrics & Gynecology, Al-Galaa Teaching Maternity Hospital, Egypt
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Fathia H. Hasanain
Department of Obstetrics & Gynecology, King Abdul Aziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia. Tel. +966 (2) 6313072/6312850/6401000. Fax. +966 (2) 6408316/6313072.
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Bothina K. Greiew
Department of Obstetrics & Gynecology, Al-Jamahiriya Hospital, Benghazi, Libya.
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Abstract

OBJECTIVE: To assess the presentation, different surgical modalities and their outcome in the treatment of polycystic ovarian disease.

METHODS: A retrospective study was carried out on 66 patients with polycystic ovarian disease. The majority of the cases had a history of infertility for at least 2 years and were known to be clomiphene citrate resistant in the Saudi German Hospital, Jeddah between 1994 and 1998 undergoing laparoscopic ovarian drilling.

RESULTS: More than 80% of the patients were below 30 years of age. The majority of cases below 30 years had primary infertility. Irregular cycle was the main clinical presentation in 75% of cases; ovarian volume was more than 5.5cm3 in all of the cases. Diathermy drilling was carried out for 50 patients, laser for 12 patients and wedge resection for 4 patients. The follow-up treatment showed that pregnancy rate was 23%, 38% and 0% in the 3 groups. Cases that failed to conceive had significantly higher luteinizing hormone level.

CONCLUSION: Laparoscopic ovarian drilling using diathermy or laser is effective during the induction of ovulation and increases the pregnancy rate in cases of polycystic ovarian disease resistant to clomiphene citrate.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 22 (6)
Saudi Medical Journal
Vol. 22, Issue 6
1 Jun 2001
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Hope for clomiphene citrate resistant ovaries
Mahmoud N. Abdul Salam, Fathia H. Hasanain, Bothina K. Greiew
Saudi Medical Journal Jun 2001, 22 (6) 508-511;

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Hope for clomiphene citrate resistant ovaries
Mahmoud N. Abdul Salam, Fathia H. Hasanain, Bothina K. Greiew
Saudi Medical Journal Jun 2001, 22 (6) 508-511;
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© 2023 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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