Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

Brucellosis in children of Dhofar Region, Oman

Eisa O. El-Amin, Lionel George, Naryanan K. Kutty, Padam P. Sharma, Rajkunari S. Choithramani, Vandavia P. Jhaveri, Panakanadan Salil and Said M. Bedair
Saudi Medical Journal July 2001, 22 (7) 610-615;
Eisa O. El-Amin
Pediatrics Department, Khoula Hospital, PO Box 3067, PC 112, Ruwi, Muscat, Sultanate of Oman. Fax. +968 561445. E-mail: [email protected]
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Lionel George
Department of Pediatrics, Sultan Qaboos Hospital, Salalah, Sultanate of Oman.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Naryanan K. Kutty
Department of Pediatrics, Sultan Qaboos Hospital, Salalah, Sultanate of Oman.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Padam P. Sharma
Department of Pediatrics, Sultan Qaboos Hospital, Salalah, Sultanate of Oman.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rajkunari S. Choithramani
Department of Pediatrics, Sultan Qaboos Hospital, Salalah, Sultanate of Oman.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vandavia P. Jhaveri
Department of Microbiology Sultan Qaboos Hospital, Salalah, Sultanate of Oman.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Panakanadan Salil
Department of Epidemiology, Sultan Qaboos Hospital, Salalah, Sultanate of Oman.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Said M. Bedair
Department of Radiology, Sultan Qaboos Hospital, Salalah, Sultanate of Oman.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • eLetters
  • Info & Metrics
  • PDF
Loading

Abstract

OBJECTIVE: To study the epidemiological and clinical pattern of brucellosis in children of Dhofar and to ascertain the efficacy of a pre-determined antibiotic regimen to treat the disease.

METHODS: The study was hospital based and was carried out prospectively for 3 years. All cases diagnosed to have brucellosis on clinical and serological basis were entered into the study. The epidemiological background and clinical presentations were analyzed and the clinical response to a combination of oral rifampicin and co-trimoxazole was evaluated.

RESULTS: Three hundred and seventy five cases of brucellosis were eligible for the study. Ingestion of raw milk and its products were responsible for causation of the disease in 63% of cases. Eighty three per cent had direct contact with animals mainly cattle. A minority of 4.5% denied ingestion of raw milk or coming into direct contact with animals. Fever was the most common presenting feature at 91%. We identified 2 distinct groups of presentation: Seventy per cent of those who presented with arthritis belonged to the older age group (7.34 years, standard deviation 2.64). They did not have a systemic illness. The younger age group presented with severe systemic illness associated with severe leucopenia and thrombocytopenia. The clinical response to the combination of rifampicin and co-trimoxazole was satisfactory in 90% of patients and 98% of brucella species isolated from the blood of patients were sensitive to both antibiotics used.

CONCLUSION: Ingestion of infected milk and contact with infected animals are the main causes of human brucellosis, although aerial transmission from contaminated environmental soil could not be excluded. The main clinical presentation of brucellosis in children is fever but the skeletal manifestations of the disease are significant. The hematological manifestations of the disease in endemic areas deserve special attention. The combination of oral rifampicin and co-trimoxazole for 6 weeks is adequate to treat most cases of brucellosis in children.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PreviousNext
Back to top

In this issue

Saudi Medical Journal: 22 (7)
Saudi Medical Journal
Vol. 22, Issue 7
1 Jul 2001
  • Table of Contents
  • Cover (PDF)
  • Index by author
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Brucellosis in children of Dhofar Region, Oman
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
Brucellosis in children of Dhofar Region, Oman
Eisa O. El-Amin, Lionel George, Naryanan K. Kutty, Padam P. Sharma, Rajkunari S. Choithramani, Vandavia P. Jhaveri, Panakanadan Salil, Said M. Bedair
Saudi Medical Journal Jul 2001, 22 (7) 610-615;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Brucellosis in children of Dhofar Region, Oman
Eisa O. El-Amin, Lionel George, Naryanan K. Kutty, Padam P. Sharma, Rajkunari S. Choithramani, Vandavia P. Jhaveri, Panakanadan Salil, Said M. Bedair
Saudi Medical Journal Jul 2001, 22 (7) 610-615;
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • eLetters
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • The factors affecting comfort and the comfort levels of patients hospitalized in the coronary intensive care unit
  • Exploring communication challenges with children and parents among pharmacists in Saudi Arabia
  • Exploring hypothyroidism’s effects on lipid profiles
Show more Original Article

Similar Articles

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire