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Research ArticleOriginal Article
Open Access

Use of dexamethasone to reduce postoperative vomiting and pain after pediatric tonsillectomy procedures

Abdulhamid H. Samarkandi, Mussarat A. Shaikh, Rana A. Ahmad and Ahmed Y. Alammar
Saudi Medical Journal November 2004, 25 (11) 1636-1639;
Abdulhamid H. Samarkandi
Department of Anesthesia, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
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Mussarat A. Shaikh
Department of Anesthesia, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
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Rana A. Ahmad
Department of Anesthesia, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
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Ahmed Y. Alammar
Department of Anesthesia, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
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Abstract

OBJECTIVE: The purpose of this study is to determine whether a single dose of dexamethasone 0.5mg/kg administered before surgery could decrease post operative vomiting and pain and improves oral intake in the first 24-hours after pediatric tonsillectomy procedures.

METHODS: It is a randomized, double blind, placebo controlled study. Sixty children age 2-12-years ASA 1 and11 were scheduled for tonsillectomy, dexamethasone (n=29) and control group (n=31) were enrolled in the study. Dexamethasone group received 0.5mg/kg intravenous dexamethasone and control group received saline at the time of induction. The anesthetic regimen and surgical procedures were standardized for all patients. All patients were observed in post anesthesia care unit (PACU) and ward for post operative vomiting, pain, need for rescue antiemetic or analgesia and time for first oral intake for 24-hours.

RESULTS: Data from 60 patients were analyzed. The overall incidence of early as well as late vomiting was significantly less in dexamethasone as compared to control group (37% versus 74% P=0.016), overall incidence of retching was 29% in control and 3.4% in dexamethasone (p=0.008). Vomiting once or more than once was significantly high in control as compared to dexamethasone group. The need for rescue antiemetic, the time to first oral intake and analgesic requirements did not show any significant difference in both groups.

CONCLUSION: Dexamethasone is considered safe and there was no adverse effects associated with a single dose of dexamethasone. Although the need for rescue antiemetic, time to oral intake and analgesia requirements in both groups were not significant, however, we found that dexamethasone does have antiemetic properties as overall incidence of retching and vomiting was significantly less in dexamethasone group as compared to control group in children who underwent tonsillectomy.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 25 (11)
Saudi Medical Journal
Vol. 25, Issue 11
1 Nov 2004
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Use of dexamethasone to reduce postoperative vomiting and pain after pediatric tonsillectomy procedures
Abdulhamid H. Samarkandi, Mussarat A. Shaikh, Rana A. Ahmad, Ahmed Y. Alammar
Saudi Medical Journal Nov 2004, 25 (11) 1636-1639;

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Use of dexamethasone to reduce postoperative vomiting and pain after pediatric tonsillectomy procedures
Abdulhamid H. Samarkandi, Mussarat A. Shaikh, Rana A. Ahmad, Ahmed Y. Alammar
Saudi Medical Journal Nov 2004, 25 (11) 1636-1639;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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