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Review ArticleReview Article
Open Access

Immunological diagnosis of vasculitis

Khalil Abdul-Aziz and Abdul-Aziz Faizal
Saudi Medical Journal August 2006, 27 (8) 1105-1115;
Khalil Abdul-Aziz
Regional Department of Immunology, Birmingham Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, United Kingdom. Tel. +44 (121) 4240185. Fax. +44 (121) 4243229. E-mail: [email protected]
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  • For correspondence: [email protected]
Abdul-Aziz Faizal
Department of Rheumatology, Heart of England NHS Foundation Trust, Birmingham, United Kingdom.
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Abstract

Inflammation of blood vessels, or vasculitis, is caused by a heterogenous group of autoimmune conditions with wide spectrum of systemic, and often overlapping, clinical manifestations. Some of these conditions present acutely and result in major organ's damage and, therefore, require prompt diagnosis and treatment in order to avoid the high morbidity and mortality that otherwise occur. The clinical immunology laboratory plays a vital role in the diagnosis of vasculitis. Moreover, due to the availability of simple tests, with quick turn around time, immunological findings can provide an early picture of the type of vasculitis involved thereby allowing initiation of prompt treatment in life threatening situations. In the present review, we will outline the various tests available in the immunology laboratory for the investigation of vasculitides, discuss the assays used to carry out these tests and, finally, comment on the significance of the results produced in relation to the diagnosis, or exclusion, of vasculitis. We hope that such information would prove of great importance to physicians and immunologists alike and lead to more efficient diagnosis of these important and, often, life threatening conditions.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 27 (8)
Saudi Medical Journal
Vol. 27, Issue 8
1 Aug 2006
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Immunological diagnosis of vasculitis
Khalil Abdul-Aziz, Abdul-Aziz Faizal
Saudi Medical Journal Aug 2006, 27 (8) 1105-1115;

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Immunological diagnosis of vasculitis
Khalil Abdul-Aziz, Abdul-Aziz Faizal
Saudi Medical Journal Aug 2006, 27 (8) 1105-1115;
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© 2023 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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