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Research ArticleOriginal Article
Open Access

Stem cell transplantation in hematological disorders. A developing country experience-impact of cost considerations

Maha M. El-Zimaity, Essam A. Hassan, Soha E. Abd El-Wahab, Afaf A. Abd El-Ghaffar, Nazek A. Mahmoud, Amal M. Elafifi, Mohamed M. Moussa, Ghada M. El-Gohary, Mona M. Hagras and Nadia M. Mowafy
Saudi Medical Journal October 2008, 29 (10) 1484-1489;
Maha M. El-Zimaity
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Essam A. Hassan
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Soha E. Abd El-Wahab
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Afaf A. Abd El-Ghaffar
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Nazek A. Mahmoud
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Amal M. Elafifi
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Mohamed M. Moussa
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Ghada M. El-Gohary
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Mona M. Hagras
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Nadia M. Mowafy
10 elsheik Ahmed eldardiry st apt # 303, Golfland Cairo, 11361 Egypt. Tel. +202 22906848/+202 (12) 7460920. Fax. +202 25880592. E-mail: [email protected]
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Abstract

OBJECTIVE: To describe the experience in setting up a bone marrow transplant program at Ain Shams University, Cairo, Egypt.

METHODS: Sixteen patients were transplanted at Ain Shams University Bone Marrow Transplantation unit from March 2005 to January 2008.

RESULTS: Sixteen patients were transplanted with a median age of 25 years. Indications for transplantation were chronic myeloid leukemia, acute myeloid leukemia, aplastic anemia, acute lymphoblastic leukemia, and aggressive lymphoma. Seven donors and 6 patients were positive for cytomegalovirus immunoglobulin G (IgG) antibody (Ab) pretransplant. Only one patient was positive for toxoplasma IgG Ab and another had a high titre for toxoplasma IgM Ab pretransplant. Two donors and 2 recipients were positive for hepatitis B antibody markers; however, none were positive for hepatitis B virus DNA by polymerase chain reaction (PCR). None of the patients or donors were positive for hepatitis C virus via PCR pre-transplant. Acute graft versus host disease (GVHD) was seen in 3 patients, while chronic GVHD was seen in 5 patients. Primary cause of death was recurrence in 2 patients and graft failure in one patient. Thirteen are alive and disease free with a median follow-up of 20 months.

CONCLUSION: Although our unit is a relatively new unit, these results are comparable to those achieved in the Western world and cost a mean of US$250,000.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 29 (10)
Saudi Medical Journal
Vol. 29, Issue 10
1 Oct 2008
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Stem cell transplantation in hematological disorders. A developing country experience-impact of cost considerations
Maha M. El-Zimaity, Essam A. Hassan, Soha E. Abd El-Wahab, Afaf A. Abd El-Ghaffar, Nazek A. Mahmoud, Amal M. Elafifi, Mohamed M. Moussa, Ghada M. El-Gohary, Mona M. Hagras, Nadia M. Mowafy
Saudi Medical Journal Oct 2008, 29 (10) 1484-1489;

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Stem cell transplantation in hematological disorders. A developing country experience-impact of cost considerations
Maha M. El-Zimaity, Essam A. Hassan, Soha E. Abd El-Wahab, Afaf A. Abd El-Ghaffar, Nazek A. Mahmoud, Amal M. Elafifi, Mohamed M. Moussa, Ghada M. El-Gohary, Mona M. Hagras, Nadia M. Mowafy
Saudi Medical Journal Oct 2008, 29 (10) 1484-1489;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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