Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

An inverse relation between CagA+ strains of Helicobacter pylori infection and risk of erosive GERD

Mohammad H. Somi, Ebrahim Fattahi, Rohollah F. Fouladi, Mohsen Karimi, Reza Bonyadi and Zohreh Baballou
Saudi Medical Journal March 2008, 29 (3) 393-396;
Mohammad H. Somi
Liver & Gastroenterology Diseases Research Center (LGDRG), Tabriz Medical Sciences University, Tabriz, Iran. Tel/Fax. +98 (411) 3352079. E-mail: [email protected]
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Ebrahim Fattahi
Liver & Gastroenterology Diseases Research Center (LGDRG), Tabriz Medical Sciences University, Tabriz, Iran. Tel/Fax. +98 (411) 3352079. E-mail: [email protected]
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Rohollah F. Fouladi
Liver & Gastroenterology Diseases Research Center (LGDRG), Tabriz Medical Sciences University, Tabriz, Iran. Tel/Fax. +98 (411) 3352079. E-mail: [email protected]
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Mohsen Karimi
Liver & Gastroenterology Diseases Research Center (LGDRG), Tabriz Medical Sciences University, Tabriz, Iran. Tel/Fax. +98 (411) 3352079. E-mail: [email protected]
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Reza Bonyadi
Liver & Gastroenterology Diseases Research Center (LGDRG), Tabriz Medical Sciences University, Tabriz, Iran. Tel/Fax. +98 (411) 3352079. E-mail: [email protected]
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Zohreh Baballou
Liver & Gastroenterology Diseases Research Center (LGDRG), Tabriz Medical Sciences University, Tabriz, Iran. Tel/Fax. +98 (411) 3352079. E-mail: [email protected]
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
  • Article
  • eLetters
  • Info & Metrics
  • PDF
Loading

Abstract

OBJECTIVE: The aim of this study is investigating the association of Helicobacter pylori H. pylori infection and its cytotoxic-associated gene A cagA strain with reflux esophagitis.

METHODS: In a case-control setting May 2005-2006, patients with reflux esophagitis case group were compared with age and gender matched people suffering from symptoms of gastroesophageal reflux disease with normal upper gastrointestinal endoscopic findings control group in Imam Khomeini Hospital, Tabriz, Iran. The rates of H. pylori and its cagA positive infections were separately compared between the 2 groups and the subgroups with different severity of reflux esophagitis.

RESULTS: Ninety-two and 93 patients were enrolled in the case and the control groups. The rate of H. pylori infection was insignificantly lower in the case group 81.5% versus 87.10%, p=0.29, odd ratio 0.654, 95% Confidence interval [CI] 0.293 to 1.495. The CagA positive infections were found significantly more frequent in the control group 59.1% versus 40.2%, p=0.01, odd ratio 0.465, 95% CI 0.258 to 0.836. There was no significant difference between the severity subgroups of the disease for H. pylori p=0.30 or cagA positive infection rates p=0.40.

CONCLUSION: The CagA positive strains might have a protective effect against reflux esophagitis.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PreviousNext
Back to top

In this issue

Saudi Medical Journal: 29 (3)
Saudi Medical Journal
Vol. 29, Issue 3
1 Mar 2008
  • Table of Contents
  • Cover (PDF)
  • Index by author
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
An inverse relation between CagA+ strains of Helicobacter pylori infection and risk of erosive GERD
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
An inverse relation between CagA+ strains of Helicobacter pylori infection and risk of erosive GERD
Mohammad H. Somi, Ebrahim Fattahi, Rohollah F. Fouladi, Mohsen Karimi, Reza Bonyadi, Zohreh Baballou
Saudi Medical Journal Mar 2008, 29 (3) 393-396;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
An inverse relation between CagA+ strains of Helicobacter pylori infection and risk of erosive GERD
Mohammad H. Somi, Ebrahim Fattahi, Rohollah F. Fouladi, Mohsen Karimi, Reza Bonyadi, Zohreh Baballou
Saudi Medical Journal Mar 2008, 29 (3) 393-396;
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • eLetters
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • The risk factors for cardiovascular disease and chronic kidney disease in patients with nonalcoholic fatty liver disease in Saudi Arabia
  • Prolonged flight exposure and its effects on sinonasal health among aircrew members
  • Identifying individuals at risk of post-stroke depression
Show more Original Article

Similar Articles

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire