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Research ArticleOriginal Article
Open Access

Investigation of the effect of ginger on the lipid levels. A double blind controlled clinical trial.

Reza Alizadeh-Navaei, Fatemeh Roozbeh, Mehrdad Saravi, Mehdi Pouramir, Farzad Jalali and Ali A. Moghadamnia
Saudi Medical Journal September 2008, 29 (9) 1280-1284;
Reza Alizadeh-Navaei
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Fatemeh Roozbeh
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Mehrdad Saravi
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Mehdi Pouramir
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Farzad Jalali
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Ali A. Moghadamnia
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Abstract

OBJECTIVES To study the effect of fine powder of ginger on lipid level in volunteer patients. METHODS This is a double blind controlled clinical trial study in 2 cardiac clinics Cardiac Disease Clinic, Babol, north of Iran, between April to May 2004. We randomly divided the patients with hyperlipidemia into 2 groups, treatment group (receiving ginger capsules 3 g/day in 3 divided doses) and placebo group (lactose capsule 3 g/day in 3 divided doses) for 45 days. All subjects with diabetes mellitus, hypothyroidism, nephrotic syndrome, and alcohol drinking, pregnancy and peptic ulcer were excluded. Lipid concentrations profile before and after treatment was measured by enzymatic assay. RESULTS Forty-five patients in the treatment group and 40 patients in placebo group participated in this study. There was a significant reduce in triglyceride, cholesterol, low density lipoprotein (LDL), very low density lipoprotein (VLDL), levels of before and after study separately in each group (p<0.05). Mean changes in triglyceride and cholesterol levels of ginger group were significantly higher than placebo group (p<0.05). Mean reduction in LDL level and increase in high density lipoprotein level of ginger group were higher than the placebo group, but in VLDL level of placebo was higher than ginger (p>0.05). CONCLUSIONS The results show that ginger has a significant lipid lowering effect compared to placebo.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 29 (9)
Saudi Medical Journal
Vol. 29, Issue 9
1 Sep 2008
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Investigation of the effect of ginger on the lipid levels. A double blind controlled clinical trial.
Reza Alizadeh-Navaei, Fatemeh Roozbeh, Mehrdad Saravi, Mehdi Pouramir, Farzad Jalali, Ali A. Moghadamnia
Saudi Medical Journal Sep 2008, 29 (9) 1280-1284;

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Investigation of the effect of ginger on the lipid levels. A double blind controlled clinical trial.
Reza Alizadeh-Navaei, Fatemeh Roozbeh, Mehrdad Saravi, Mehdi Pouramir, Farzad Jalali, Ali A. Moghadamnia
Saudi Medical Journal Sep 2008, 29 (9) 1280-1284;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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