Prevalence, clinical characteristics, and predictors of obesity hypoventilation syndrome in a large sample of Saudi patients with obstructive sleep apnea

References

1. ↵
   1. Punjabi NM

   (2008) The epidemiology of adult obstructive sleep apnea. Proc Am Thorac Soc 5:136–143.

   OpenUrlCrossRefPubMed
2. ↵
   1. Al Dabal L,
   2. Bahammam AS

   (2009) Obesity hypoventilation syndrome. Ann Thorac Med 4:41–49.

   OpenUrlCrossRefPubMed
3. ↵
   1. Auchincloss JH Jr.,
   2. Cook E,
   3. Renzetti AD

   (1955) Clinical and physiological aspects of a case of obesity, polycythemia and alveolar hypoventilation. J Clin Invest 34:1537–1545.

   OpenUrlCrossRefPubMedWeb of Science
4. ↵
   1. American Academy of Sleep Medicine

   (2014) International classification of sleep disorders (ICSD) (American Academy of Sleep Medicine, Darien (IL)), 3rd ed.
5. ↵
   1. Pépin JL,
   2. Borel JC,
   3. Janssens JP

   (2012) Obesity hypoventilation syndrome: an underdiagnosed and undertreated condition. Am J Respir Crit Care Med 186:1205–1207.

   OpenUrlCrossRefPubMed
6. ↵
   1. BaHammam A,
   2. Syed S,
   3. Al-Mughairy A

   (2005) Sleep-related breathing disorders in obese patients presenting with acute respiratory failure. Respir Med 99:718–725.

   OpenUrlCrossRefPubMedWeb of Science
7. ↵
   1. Berg G,
   2. Delaive K,
   3. Manfreda J,
   4. Walld R,
   5. Kryger MH

   (2001) The use of health-care resources in obesity-hypoventilation syndrome. Chest 120:377–383.

   OpenUrlCrossRefPubMedWeb of Science
8. ↵
   1. BaHammam A

   (2010) Acute ventilatory failure complicating obesity hypoventilation: update on a ’critical care syndrome’ Curr Opin Pulm Med 16:543–551.

   OpenUrlCrossRefPubMed
9. ↵
   1. Miller MR,
   2. Hankinson J,
   3. Brusasco V,
   4. Burgos F,
   5. Casaburi R,
   6. Coates A,
   7. et al.

   (2005) Standardisation of spirometry. Eur Respir J 26:319–338.

   OpenUrlAbstract/FREE Full Text
10. ↵
    1. Johns MW

    (1992) Reliability and factor analysis of the Epworth Sleepiness Scale. Sleep 15:376–381.

    OpenUrlCrossRefPubMedWeb of Science
11. ↵
    1. Berry RB,
    2. Brooks R,
    3. Gamaldo CE,
    4. Harding SM,
    5. Lloyd RM,
    6. Marcus CL,
    7. et al.

    (2014) The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications (American Academy of Sleep Medicine, Darien (IL)) Available from URL: http://www.aasmnet.org. updated January 2014. Version 2.1.
12. ↵
    1. Bursac Z,
    2. Gauss CH,
    3. Williams DK,
    4. Hosmer DW

    (2008) Purposeful selection of variables in logistic regression. Source Code Biol Med 3:17.

    OpenUrlCrossRefPubMed
13. ↵
    1. Mokhlesi B,
    2. Kryger MH,
    3. Grunstein RR

    (2008) Assessment and management of patients with obesity hypoventilation syndrome. Proc Am Thorac Soc 5:218–225.

    OpenUrlCrossRefPubMed
14. ↵
    1. Akashiba T,
    2. Akahoshi T,
    3. Kawahara S,
    4. Uematsu A,
    5. Katsura K,
    6. Sakurai S,
    7. et al.

    (2006) Clinical characteristics of obesity-hypoventilation syndrome in Japan: a multi-center study. Intern Med 45:1121–1125.

    OpenUrlCrossRefPubMed
15. ↵
    1. Alzaabi A,
    2. Fizal S,
    3. Moilothkandy R,
    4. Mahboub B,
    5. Nagelkerke N

    (2013) Obesity hypoventilation syndrome in obstructive sleep apnea patients in the United Arab Emirates: a retrospective cross-sectional study. JRSM Short Rep 4:2042533313510156.
16. 1. Golpe R,
    2. Jiménez A,
    3. Carpizo R

    (2002) Diurnal hypercapnia in patients with obstructive sleep apnea syndrome. Chest 122:1100–1101.

    OpenUrlCrossRefPubMedWeb of Science
17. 1. Kessler R,
    2. Chaouat A,
    3. Schinkewitch P,
    4. Faller M,
    5. Casel S,
    6. Krieger J,
    7. et al.

    (2001) The obesity-hypoventilation syndrome revisited: a prospective study of 34 consecutive cases. Chest 120:369–376.

    OpenUrlCrossRefPubMedWeb of Science
18. ↵
    1. Laaban JP,
    2. Chailleux E

    (2005) Daytime hypercapnia in adult patients with obstructive sleep apnea syndrome in France, before initiating nocturnal nasal continuous positive airway pressure therapy. Chest 127:710–715.

    OpenUrlCrossRefPubMedWeb of Science
19. 1. Resta O,
    2. Foschino Barbaro MP,
    3. Bonfitto P,
    4. Talamo S,
    5. Mastrosimone V,
    6. Stefano A,
    7. et al.

    (2000) Hypercapnia in obstructive sleep apnoea syndrome. Neth J Med 56:215–222.

    OpenUrlCrossRefPubMedWeb of Science
20. ↵
    1. Trakada GP,
    2. Steiropoulos P,
    3. Nena E,
    4. Constandinidis TC,
    5. Bouros D

    (2010) Prevalence and clinical characteristics of obesity hypoventilation syndrome among individuals reporting sleep-related breathing symptoms in northern Greece. Sleep Breath 14:381–386.

    OpenUrlCrossRefPubMed
21. 1. Verin E,
    2. Tardif C,
    3. Pasquis P

    (2001) Prevalence of daytime hypercapnia or hypoxia in patients with OSAS and normal lung function. Respir Med 95:693–696.

    OpenUrlCrossRefPubMedWeb of Science
22. ↵
    1. Mokhlesi B,
    2. Tulaimat A,
    3. Faibussowitsch I,
    4. Wang Y,
    5. Evans AT

    (2007) Obesity hypoventilation syndrome: prevalence and predictors in patients with obstructive sleep apnea. Sleep Breath 11:117–124.

    OpenUrlCrossRefPubMedWeb of Science
23. ↵
    1. Mokhlesi B

    (2010) Obesity hypoventilation syndrome: a state-of-the-art review. Respir Care 55:1347–1362, discussion 1363-1365.

    OpenUrlAbstract/FREE Full Text
24. 1. Nowbar S,
    2. Burkart KM,
    3. Gonzales R,
    4. Fedorowicz A,
    5. Gozansky WS,
    6. Gaudio JC,
    7. et al.

    (2004) Obesity-associated hypoventilation in hospitalized patients: prevalence, effects, and outcome. Am J Med 116:1–7.

    OpenUrlCrossRefPubMedWeb of Science
25. ↵
    1. Masa JF,
    2. Celli BR,
    3. Riesco JA,
    4. Hernández M,
    5. Sánchez De Cos J,
    6. Disdier C

    (2001) The obesity hypoventilation syndrome can be treated with noninvasive mechanical ventilation. Chest 119:1102–1107.

    OpenUrlCrossRefPubMedWeb of Science
26. ↵
    1. Alotair H,
    2. Bahammam A

    (2008) Gender differences in Saudi patients with obstructive sleep apnea. Sleep Breath 12:323–329.

    OpenUrlPubMed
27. ↵
    1. Young T,
    2. Finn L,
    3. Austin D,
    4. Peterson A

    (2003) Menopausal status and sleep-disordered breathing in the Wisconsin Sleep Cohort Study. Am J Respir Crit Care Med 167:1181–1185.

    OpenUrlCrossRefPubMedWeb of Science
28. ↵
    1. Kanter R,
    2. Caballero B

    (2012) Global gender disparities in obesity: a review. Adv Nutr 3:491–498.

    OpenUrlAbstract/FREE Full Text
29. ↵
    1. Martin SS,
    2. Qasim A,
    3. Reilly MP

    (2008) Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease. J Am Coll Cardiol 52:1201–1210.

    OpenUrlFREE Full Text
30. ↵
    1. Polotsky VY,
    2. Wilson JA,
    3. Smaldone MC,
    4. Haines AS,
    5. Hurn PD,
    6. Tankersley CG,
    7. et al.

    (2001) Female gender exacerbates respiratory depression in leptin-deficient obesity. Am J Respir Crit Care Med 164:1470–1475.

    OpenUrlCrossRefPubMedWeb of Science
31. ↵
    1. Phipps PR,
    2. Starritt E,
    3. Caterson I,
    4. Grunstein RR

    (2002) Association of serum leptin with hypoventilation in human obesity. Thorax 57:75–76.

    OpenUrlAbstract/FREE Full Text
32. ↵
    1. Shimura R,
    2. Tatsumi K,
    3. Nakamura A,
    4. Kasahara Y,
    5. Tanabe N,
    6. Takiguchi Y,
    7. et al.

    (2005) Fat accumulation, leptin, and hypercapnia in obstructive sleep apnea-hypopnea syndrome. Chest 127:543–549.

    OpenUrlCrossRefPubMedWeb of Science
33. ↵
    1. Kapsimalis F,
    2. Kryger MH

    (2002) Gender and obstructive sleep apnea syndrome, part 2: mechanisms. Sleep 25:499–506.

    OpenUrlPubMedWeb of Science
34. ↵
    1. BaHammam A

    (2007) Is apnea hypopnea index a good predictor for obesity hypoventilation syndrome in patients with obstructive sleep apnea? Sleep Breath 11:201, author reply 203-204.

    OpenUrlPubMed
35. ↵
    1. Kaw R,
    2. Hernandez AV,
    3. Walker E,
    4. Aboussouan L,
    5. Mokhlesi B

    (2009) Determinants of hypercapnia in obese patients with obstructive sleep apnea: a systematic review and metaanalysis of cohort studies. Chest 136:787–796.

    OpenUrlCrossRefPubMedWeb of Science
36. ↵
    1. Borel JC,
    2. Borel AL,
    3. Monneret D,
    4. Tamisier R,
    5. Levy P,
    6. Pepin JL

    (2012) Obesity hypoventilation syndrome: from sleep-disordered breathing to systemic comorbidities and the need to offer combined treatment strategies. Respirology 17:601–610.

    OpenUrlPubMed
37. ↵
    1. Budweiser S,
    2. Riedl SG,
    3. Jörres RA,
    4. Heinemann F,
    5. Pfeifer M

    (2007) Mortality and prognostic factors in patients with obesity-hypoventilation syndrome undergoing noninvasive ventilation. J Intern Med 261:375–383.

    OpenUrlCrossRefPubMedWeb of Science
38. ↵
    1. Borel JC,
    2. Burel B,
    3. Tamisier R,
    4. Dias-Domingos S,
    5. Baguet JP,
    6. Levy P,
    7. et al.

    (2013) Comorbidities and mortality in hypercapnic obese under domiciliary noninvasive ventilation. PLoS One 8:e52006.

    OpenUrlCrossRefPubMed
39. ↵
    1. Quint JK,
    2. Ward L,
    3. Davison AG

    (2007) Previously undiagnosed obesity hypoventilation syndrome. Thorax 62:462–463.

    OpenUrlFREE Full Text
40. ↵
    1. Pérez de Llano LA,
    2. Golpe R,
    3. Ortiz Piquer M,
    4. Veres Racamonde A,
    5. Vázquez Caruncho M,
    6. Caballero Muinelos O,
    7. et al.

    (2005) Short-term and long-term effects of nasal intermittent positive pressure ventilation in patients with obesity-hypoventilation syndrome. Chest 128:587–594.

    OpenUrlCrossRefPubMedWeb of Science
41. ↵
    1. Bahammam AS,
    2. Al-Jawder SE

    (2012) Managing acute respiratory decompensation in the morbidly obese. Respirology 17:759–771.

    OpenUrlCrossRefPubMed