Review ArticleReview Article
Open Access

The potential role of microbes in oncogenesis with particular emphasis on oral cancer

Asmaa A. Faden
Saudi Medical Journal June 2016, 37 (6) 607-612; DOI: https://doi.org/10.15537/smj.2016.6.14048

References

  1. ↵
    1. Rodrigues VC,
    2. Moss SM,
    3. Tuomainen H
    (1998) Oral cancer in the UK: to screen or not to screen. Oral Oncol 34:454–465.
    OpenUrlCrossRefPubMedWeb of Science
  2. ↵
    1. Chen AY,
    2. Myers JN
    (2000) Cancer of the oral cavity. Curr Probl Surg 37:633–731.
    OpenUrlPubMed
  3. ↵
    1. Silverman S Jr.
    (2003) Oral Cancer (American Cancer Society Atlas of Clinical Oncology) (PMPH USA, Shelton (CT)), 5th ed.
  4. ↵
    1. Hindle I,
    2. Downer MC,
    3. Moles DR,
    4. Speight PM
    (2000) Is alcohol responsible for more intra-oral cancer? Oral Oncol 36:328–333.
    OpenUrlCrossRefPubMed
  5. ↵
    1. Brown KR
    (2006) The unequal burden related to the risk of oral cancer in the different regions of the Kingdom of Saudi Arabia. Community Dent Health 23:101–106.
    OpenUrlPubMed
  6. ↵
    1. Wainwright M
    (2002) Do fungi play a role in the aetiology of cancer? Reviews in Medical Microbiology 13:37–42.
    OpenUrl
  7. ↵
    1. Wainwright M
    (2010) The overlooked link between non-virus microbes and cancer. Sci Prog 93:393–402.
    OpenUrlCrossRefPubMed
  8. ↵
    1. Mager D
    (2006) Bacteria and cancer: cause, coincidence or cure? A review. J Transl Med 28:14.
    OpenUrl
  9. ↵
    1. Schwabe RF,
    2. Jobin C
    (2013) The microbiome and cancer. Nat Rev Cancer 13:800–812.
    OpenUrlCrossRefPubMedWeb of Science
  10. ↵
    1. Dudgeon LS,
    2. Dunkley EV
    (1906) The Micrococcus neoformans. Epidemiol Infect 7:13–21.
    OpenUrl
  11. ↵
    1. Cantwell A
    (1990) The cancer microbe (Aries Rising Press, Los Angeles (CA)), p 283.
  12. ↵
    1. Cantwell A
    (2005) Four women against cancer (Aries Rising Press, Los Angeles (CA)), 144.
  13. ↵
    1. Wainwright M
    (1998) Hypothesis-can UV produced by intracellular bacteria cause cancer? Microbiology 144(Pt 12):3239–3240.
    OpenUrlCrossRefPubMed
  14. ↵
    1. Wainwright M,
    2. De Wulf P,
    3. Tao T,
    4. Grulich P,
    5. Kucharski L,
    6. Smith R
    (1998) When heresies collide - extreme bacterial pleomorphism and the cancer germ. Microbiology 144:595–596.
    OpenUrlCrossRefPubMed
  15. ↵
    1. Wainwright M
    (1998) James Young and the “cancer germ” J Med Biogr 6:203–205.
    OpenUrlCrossRefPubMed
  16. ↵
    1. Wainwright M,
    2. Al Talih A
    (2003) Is this the historical “cancer germ”? Med Hypotheses 60:290–292.
    OpenUrlCrossRefPubMedWeb of Science
  17. ↵
    1. Wainwright M
    (1999) Nanobacteria and associated ‘elementary bodies’ in human disease and cancer. Microbiology 145:2623–2624.
    OpenUrlPubMed
  18. ↵
    1. Marshall BJ
    (1995) The 1995 Albert Lasker Medical Research Award Helicobacter pylori. The etiologic agent for peptic ulcer. JAMA 274:1064–1066.
    OpenUrlCrossRefPubMedWeb of Science
  19. ↵
    1. Kim SS,
    2. Ruiz VE,
    3. Carroll JD,
    4. Moss SF
    (2011) Helicobacter pylori in the pathogenesis of gastric cancer and gastric lymphoma. Cancer Lett 305:228–238.
    OpenUrlCrossRefPubMedWeb of Science
  20. ↵
    1. Crowe SE
    (2005) Helicobacter infection, chronic inflammation, and the development of malignancy. Curr Opin Gastroenterol 21:32–38.
    OpenUrlPubMedWeb of Science
  21. ↵
    1. Morrissey D,
    2. O’Sullivan G,
    3. Tangney M
    (2010) Tumour targeting with systemically administered bacteria. Curr Gene Ther 10:3–14.
    OpenUrlCrossRefPubMedWeb of Science
  22. ↵
    1. Michaud DS
    (2013) Role of bacterial infections in pancreatic cancer. Carcinogenesis 34:2193–2197.
    OpenUrlCrossRefPubMed
  23. ↵
    1. Koyi H,
    2. Brandén E,
    3. Gnarpe J,
    4. Gnarpe H,
    5. Steen B
    (2001) An association between chronic infection with Chlamydia pneumoniae and lung cancer. A prospective 2-year study note. APMIS 109:72–80.
    OpenUrl
  24. ↵
    1. Welton J,
    2. Marr J,
    3. Friedman S
    (1979) Association between hepatobiliary cancer and typhoid carrier state. Lancet 313:791–794.
    OpenUrlCrossRef
  25. ↵
    1. Khan AA
    1. Ferreccio C
    (2012) in Bacteria and cancer, Salmonella typhi and Gallbladder cancer, ed Khan AA (Springer, Dordrecht (NL)), pp 117–137.
  26. ↵
    1. Lax AJ,
    2. Thomas W
    (2002) How bacteria could cause cancer: one step at a time. Trends Microbiol 10:293–299.
    OpenUrlCrossRefPubMedWeb of Science
  27. ↵
    1. Ellmerich S,
    2. Schöller M,
    3. Duranton B,
    4. Gossé F,
    5. Galluser M,
    6. Klein JP,
    7. et al.
    (2000) Promotion of intestinal carcinogenesis by Streptococcus bovis. Carcinogenesis 21:753–756.
    OpenUrlCrossRefPubMedWeb of Science
  28. ↵
    1. zur Hausen H
    (2006) Streptococcus bovis: Causal or incidental involvement in cancer of the colon? Int J Cancer 1(119):xi–xii.
    OpenUrl
  29. ↵
    1. Gately S
    (2000) The contributions of cyclooxygenase-2 to tumor angiogenesis. Cancer Metastasis Rev 19:19–27.
    OpenUrlCrossRefPubMedWeb of Science
  30. ↵
    1. Viljoen KS,
    2. Dakshinamurthy A,
    3. Goldberg P,
    4. Blackburn JM
    (2015) Quantitative profiling of colorectal cancer-associated bacteria reveals associations between fusobacterium spp., enterotoxigenic Bacteroides fragilis (ETBF) and clinicopathological features of colorectal cancer. PloS One 10:e0119462.
    OpenUrlCrossRefPubMed
  31. ↵
    1. Hooper SJ,
    2. Crean SJ,
    3. Fardy MJ,
    4. Lewis MA,
    5. Spratt DA,
    6. Wade WG,
    7. et al.
    (2008) A molecular analysis of the bacteria present within oral squamous cell carcinoma. J Med Microbiol 56:1651–1659.
    OpenUrl
  32. ↵
    1. Hooper SJ,
    2. Wilson MJ,
    3. Crean SJ
    (2009) Exploring the link between microorganisms and oral cancer: a systematic review of the literature. Head Neck 31:1228–1239.
    OpenUrlCrossRefPubMedWeb of Science
  33. ↵
    1. Hajishengallis G,
    2. Lamont RJ
    (2012) Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology. Mol Oral Microbiol 27:409–419.
    OpenUrlCrossRefPubMedWeb of Science
  34. ↵
    1. Whitmore SE,
    2. Lamont RJ
    (2014) Oral bacteria and cancer. PLoS Pathog 10:e1003933.
    OpenUrlCrossRefPubMed
  35. ↵
    1. Chocolatewala N,
    2. Chaturvedi P,
    3. Desale R
    (2010) The role of bacteria in oral cancer. Indian J Med Paediatr Oncol 31:126–131.
    OpenUrlPubMed
  36. ↵
    1. Raghunand N,
    2. Gatenby RA,
    3. Gillies RJ
    (2003) Microenvironmental and cellular consequences of altered blood flow in tumors. Br J Radiol 76:S11–S22.
    OpenUrlAbstract/FREE Full Text
  37. ↵
    1. Rakoff-Nahoum S
    (2006) Why cancer and inflammation? Yale J Biol Med 79:123–130.
    OpenUrlPubMed
  38. ↵
    1. Sasaki H,
    2. Ishizuka T,
    3. Muto M,
    4. Nezu M,
    5. Nakanishi Y,
    6. Inagaki Y,
    7. et al.
    (1998) Presence of Streptococcus anginosus DNA in esophageal cancer, dysplasia of esophagus, and gastric cancer. Cancer Res 58:2991–2995.
    OpenUrlAbstract/FREE Full Text
  39. ↵
    1. Shiga K,
    2. Tateda M,
    3. Saijo S,
    4. Hori T,
    5. Sato I,
    6. Tateno H,
    7. et al.
    (2001) Presence of Streptococcus infection extra-orpharyngeal head neck squamous cell carcinoma and its implication in carcinogenesis. Oncol Rep 8:245–248.
    OpenUrlPubMed
  40. ↵
    1. Katz J,
    2. Onate MD,
    3. Pauley KM,
    4. Bhattacharyya I,
    5. Cha S
    (2011) Presence of Porphyromonas gingivalis in gingival squamous cell carcinoma. Int J Oral Sci 3:209–215.
    OpenUrlCrossRefPubMed
  41. ↵
    1. Moore PS,
    2. Chang Y
    (2010) Why do viruses cause cancer?Highlights of the first century of human tumour virology. Nat Rev Cancer 10:878–889.
    OpenUrlCrossRefPubMedWeb of Science
  42. ↵
    1. Nagy KN,
    2. Sonkodi I,
    3. Szöke I,
    4. Nagy E,
    5. Newman HN
    (1998) The microflora associated with human oral carcinomas. Oral Oncol 34:304–308.
    OpenUrlCrossRefPubMedWeb of Science
  43. ↵
    1. McCoy AN,
    2. Araújo-Pérez F,
    3. Azcárate-Peril A,
    4. Yeh JJ,
    5. Sandler RS,
    6. Keku TO
    (2013) Fusobacterium is associated with colorectal adenomas. PLoS ONE 8:e53653.
    OpenUrlCrossRefPubMed
  44. ↵
    1. Castellarin M,
    2. Warren RL,
    3. Freeman JD,
    4. Dreolini L,
    5. Krzywinski M,
    6. Strauss J,
    7. et al.
    (2012) Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Res 22:299–306.
    OpenUrlAbstract/FREE Full Text
  45. ↵
    1. Yilmaz Ö,
    2. Yao L,
    3. Maeda K,
    4. Rose TM,
    5. Lewis EL,
    6. Duman M,
    7. et al.
    (2008) ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis. Cell Microbiol 10:863–875.
    OpenUrlCrossRefPubMed
  46. ↵
    1. Nougayrède JP,
    2. Taieb F,
    3. Rycke JD,
    4. Oswald E
    (2005) Cyclomodulins: bacterial effectors that modulate the eukaryotic cell cycle. Trends Microbiol 13:103–110.
    OpenUrlCrossRefPubMedWeb of Science
  47. ↵
    1. Coussens LM,
    2. Werb Z
    (2002) Inflammation and cancer. Nature 420:860–867.
    OpenUrlCrossRefPubMedWeb of Science
  48. ↵
    1. Calmels S,
    2. Ohshima H,
    3. Vincent P,
    4. Gounot AM,
    5. Bartsch H
    (1985) Screening of microorganisms for nitrosation catalysis at pH 7 and kinetic studies on nitrosamine formation from secondary amines by E. coli strains. Carcinogenesis 6:911–915.
    OpenUrlCrossRefPubMedWeb of Science
  49. ↵
    1. Salaspuro MP
    (2003) Acetaldehyde, microbes, and cancer of the digestive tract. Crit Rev Clin Lab Sci 40:183–208.
    OpenUrlCrossRefPubMedWeb of Science
  50. ↵
    1. Langenbach R,
    2. Nesnow S,
    3. Rice JM
    1. Lijinsky W
    (1983) in Organ and species specificity in chemical carcinogenesis, Species specificity in nitrosamine carcinogenesis, eds Langenbach R, Nesnow S, Rice JM (Springer-Verlag, New York (NY)), pp 63–75.
  51. ↵
    1. Biarc J,
    2. Nguyen IS,
    3. Pini A,
    4. Gossé F,
    5. Richert S,
    6. Thiersé D,
    7. et al.
    (2004) Carcinogenic properties of proteins with pro-inflammatory activity from Streptococcus infantarius (formerly S. bovis ). Carcinogenesis 25:1477–1484.
    OpenUrlCrossRefPubMedWeb of Science
  52. ↵
    1. Han YW,
    2. Wang X
    (2013) Mobile microbiome: oral bacteria in extra-oral infections and inflammation. J Dent Res 92:485–491.
    OpenUrlCrossRefPubMed
  53. ↵
    1. Kostic AD,
    2. Gevers D,
    3. Pedamallu CS,
    4. Michaud M,
    5. Duke F,
    6. Earl AM,
    7. et al.
    (2012) Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res 22:292–298.
    OpenUrlAbstract/FREE Full Text
  54. ↵
    1. Takeuchi H,
    2. Hirano T,
    3. Whitmore SE,
    4. Morisaki I,
    5. Amano A,
    6. Lamont RJ
    (2013) The Serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-kB RelA/p65. PLoS Pathog 9:e1003326.
    OpenUrlCrossRefPubMed
  55. ↵
    1. Kerr AR
    (2015) The oral microbiome and cancer. J Dent Hyg 89:20–23.
    OpenUrlFREE Full Text
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