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Research ArticleOriginal Article
Open Access

Risk factors and molecular features of extended-spectrum beta-lactamase producing bacteria at southwest of Saudi Arabia

Saleh M. Al-Garni, Mabrouk M. Ghonaim, Mohamed Morsi M. Ahmed, Ali S. Al-Ghamdi and Farooq A. Ganai
Saudi Medical Journal December 2018, 39 (12) 1186-1194; DOI: https://doi.org/10.15537/smj.2018.12.23273
Saleh M. Al-Garni
From the Department of Biological Sciences (Al-Garni, Ahmed, Al-Ghamdi), Faculty of Science, King Abdulaziz University, Jeddah, from the Department of Microbiology (Ganai), CAP Accredited LAB, King Abdulaziz Specialist Hospital, Taif, Kingdom of Saudi Arabia, from the Department of Medical Microbiology & Immunology (Ghonaim), Faculty of Medicine, Menoufia University, Shebin El-Kom, and from the Department of Nucleic Acids Research (Ahmed), Genetic Engineering and Biotechnology Research Institute, Mubarak City for Scientific Research and Technology Applications, Alexandria, Egypt
MS, PhD
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Mabrouk M. Ghonaim
From the Department of Biological Sciences (Al-Garni, Ahmed, Al-Ghamdi), Faculty of Science, King Abdulaziz University, Jeddah, from the Department of Microbiology (Ganai), CAP Accredited LAB, King Abdulaziz Specialist Hospital, Taif, Kingdom of Saudi Arabia, from the Department of Medical Microbiology & Immunology (Ghonaim), Faculty of Medicine, Menoufia University, Shebin El-Kom, and from the Department of Nucleic Acids Research (Ahmed), Genetic Engineering and Biotechnology Research Institute, Mubarak City for Scientific Research and Technology Applications, Alexandria, Egypt
MD, PhD
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Mohamed Morsi M. Ahmed
From the Department of Biological Sciences (Al-Garni, Ahmed, Al-Ghamdi), Faculty of Science, King Abdulaziz University, Jeddah, from the Department of Microbiology (Ganai), CAP Accredited LAB, King Abdulaziz Specialist Hospital, Taif, Kingdom of Saudi Arabia, from the Department of Medical Microbiology & Immunology (Ghonaim), Faculty of Medicine, Menoufia University, Shebin El-Kom, and from the Department of Nucleic Acids Research (Ahmed), Genetic Engineering and Biotechnology Research Institute, Mubarak City for Scientific Research and Technology Applications, Alexandria, Egypt
MS, PhD
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Ali S. Al-Ghamdi
From the Department of Biological Sciences (Al-Garni, Ahmed, Al-Ghamdi), Faculty of Science, King Abdulaziz University, Jeddah, from the Department of Microbiology (Ganai), CAP Accredited LAB, King Abdulaziz Specialist Hospital, Taif, Kingdom of Saudi Arabia, from the Department of Medical Microbiology & Immunology (Ghonaim), Faculty of Medicine, Menoufia University, Shebin El-Kom, and from the Department of Nucleic Acids Research (Ahmed), Genetic Engineering and Biotechnology Research Institute, Mubarak City for Scientific Research and Technology Applications, Alexandria, Egypt
BS, MSc
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  • For correspondence: [email protected]
Farooq A. Ganai
From the Department of Biological Sciences (Al-Garni, Ahmed, Al-Ghamdi), Faculty of Science, King Abdulaziz University, Jeddah, from the Department of Microbiology (Ganai), CAP Accredited LAB, King Abdulaziz Specialist Hospital, Taif, Kingdom of Saudi Arabia, from the Department of Medical Microbiology & Immunology (Ghonaim), Faculty of Medicine, Menoufia University, Shebin El-Kom, and from the Department of Nucleic Acids Research (Ahmed), Genetic Engineering and Biotechnology Research Institute, Mubarak City for Scientific Research and Technology Applications, Alexandria, Egypt
BS
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References

  1. ↵
    1. Zowawi HM,
    2. Balkhy HH,
    3. Walsh TR,
    4. Paterson DL
    (2013) β-Lactamase production in key gram-negative pathogen isolates from the Arabian Peninsula. Clin Microbiol Rev 26:361–380.
    OpenUrlAbstract/FREE Full Text
  2. ↵
    1. Hariri G,
    2. Tankovic J,
    3. Boëlle PY,
    4. Dubée V,
    5. Leblanc G,
    6. Pichereau C,
    7. et al.
    (2017) Are third-generation cephalosporins unavoidable for empirical therapy of community-acquired pneumonia in adult patients who require ICU admission? A retrospective study. Ann Intensive Care 7:35.
    OpenUrl
  3. ↵
    1. Ur Rahman S,
    2. Ali T,
    3. Ali I,
    4. Khan NA,
    5. Han B,
    6. Gao J
    (2018) The Growing Genetic and Functional Diversity of Extended Spectrum Beta-Lactamases. Biomed Res Int 2018:9519718.
    OpenUrl
  4. ↵
    1. Shaikh S,
    2. Fatima J,
    3. Shakil S,
    4. Rizvi SM,
    5. Kamal MA
    (2015) Antibiotic resistance and extended spectrum beta-lactamases:Types, epidemiology and treatment. Saudi J Biol Sci 22:90–101.
    OpenUrlCrossRef
  5. ↵
    1. Alsultan AA,
    2. Aboulmagd E,
    3. Amin TT
    (2013) ESBL-producing E. coli and K. pneumoniae in Al-Ahsa, Saudi Arabia:antibiotic susceptibility and prevalence of blaSHV and blaTEM. J Infect Dev Ctries 7:1016–1019.
    OpenUrl
  6. ↵
    1. Asghar AH
    (2007) Prevalence and potential types of extended spectrum beta-lactamase among Escherichia coli and Klebsiella species in Makkah hospitals. Oxf Res For J 2:47–55.
    OpenUrl
  7. ↵
    1. Fischer J,
    2. Rodríguez I,
    3. Baumann B,
    4. Guiral E,
    5. Beutin L,
    6. Schroeter A,
    7. et al.
    (2014) blaCTX-M-₁₅-carrying Escherichia coli and Salmonella isolates from livestock and food in Germany. J Antimicrob Chemother 69:2951–2958.
    OpenUrlCrossRefPubMed
  8. ↵
    1. Al-Agamy MH,
    2. Shibl AM,
    3. Hafez MM,
    4. Al-Ahdal MN,
    5. Memish ZA,
    6. Khubnani H
    (2014) Molecular characteristics of extended-spectrum ß-lactamase-producing Escherichia coli in Riyadh:emergence of CTX-M-15-producing E. coli ST131. Ann Clin Microbiol Antimicrob 13:4.
    OpenUrlCrossRefPubMed
  9. ↵
    (2012) Clinical and Laboratory Standards Institute (CLSI), Performance Standards for Antimicrobial Susceptibility Testing (Clinical and Laboratory Standards Institute, Wayne (PA)), pp M100–S22.
  10. ↵
    1. Alzahrani AK,
    2. Faraga MM,
    3. Abbadia SH,
    4. Hassanc MM,
    5. Gaberc A,
    6. Abdel-Moneima AS
    (2016) Antibiotic resistance profile and random amplification typing of β-lactamase-producing Enterobacteriaceae from the local area of Al-Taif and nearby cities in Saudi Arabia. Asian Biomed 10:219–228.
    OpenUrl
  11. ↵
    1. Elhassan MM,
    2. Ozbazk HA,
    3. Hemeg HA,
    4. Ahmed AA
    (2016) Dissemination of CTX-M extended-spectrum ß-lactamases (ESBLs) among Escherichia coli and Klebsiella pneumoniae in Al-Madenah Al-Monawwarah region, Saudi Arabia. Int J Clin Exp Med 9:11051–11057.
    OpenUrl
  12. ↵
    1. Kandeel A
    (2014) Prevalence and risk factors of extended-spectrum ß-lactamases producing Enterobacteriaceae in a general hospital in Saudi Arabia. JMID 4:50–55.
    OpenUrl
  13. ↵
    1. Zaman RM,
    2. Aly MM,
    3. Helmi NR
    (2015) Antimicrobial susceptibility pattern of Gramnegative bacilli isolated from a Teaching Hospital in Jeddah, Saudi Arabia. Afr J Microbiol Res 9:2145–2158.
    OpenUrl
  14. ↵
    1. Al Mously N,
    2. Al Arfaj O,
    3. Al Fadhil L,
    4. Mukaddam S
    (2016) Antimicrobial susceptibility patterns of ESBL Escherichia coli isolated from community and hospital acquired urinary tract infections. JHS 4:133–139.
    OpenUrl
  15. ↵
    1. Somily AM,
    2. Habib HA,
    3. Absar MM,
    4. Arshad MZ,
    5. Manneh K,
    6. Al Subaie SS,
    7. et al.
    (2014) ESBL-producing Escherichia coli and Klebsiella pneumoniae at a tertiary care hospital in Saudi Arabia. J Infect Dev Ctries 8:1129–1136.
    OpenUrl
  16. ↵
    1. Mashwal FA,
    2. El Safi SH,
    3. George SK,
    4. Adam AA,
    5. Jebakumar AZ
    (2017) Incidence and molecular characterization of the extended spectrum beta lactamase-producing Escherichia coli isolated from urinary tract infections in Eastern Saudi Arabia. Saudi Med J 38:811–815.
    OpenUrlAbstract/FREE Full Text
  17. ↵
    1. Ahmed OB,
    2. Asghar AH,
    3. Bahwerth FS
    (2015) Prevalence of ESBL gene of Pseudomonas aeruginosa strains isolated from Makkah hospitals, Saudi Arabia. European Journal of Biology and Medical Science Research 3:12–18.
    OpenUrl
  18. ↵
    1. Tham J,
    2. Odenholt I,
    3. Walder M,
    4. Andersson L,
    5. Melander E
    (2013) Risk factors for infections with extended-spectrum beta-lactamase-producing Escherichia coli in a county of Southern Sweden. Infect Drug Resist 6:93–97.
    OpenUrlPubMed
  19. ↵
    1. Peerayeh SN,
    2. Rostami E,
    3. Eslami M,
    4. Rezaee MA
    (2016) High Frequency of Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae and Escherichia coli Isolates From Male Patients'Urine. Arch Clin Infect Dis 11:e32696.
    OpenUrl
  20. ↵
    1. Denis B,
    2. Lafaurie M,
    3. Donay JL,
    4. Fontaine JP,
    5. Oksenhendler E,
    6. Raffoux E,
    7. et al.
    (2015) Prevalence, risk factors, and impact on clinical outcome of extended-spectrum beta-lactamase-producing Escherichia coli bacteraemia:a five-year study. Int J Infect Dis 39:1–6.
    OpenUrlCrossRefPubMed
  21. ↵
    1. Singh N,
    2. Pattnaik D,
    3. Neogi DK,
    4. Jena J,
    5. Mallick B
    (2016) Prevalence of ESBL in Escherichia coli Isolates Among ICU Patients in a Tertiary Care Hospital. J Clin Diagn Res 10:DC19–DC22.
    OpenUrl
  22. ↵
    1. Kassakian S,
    2. Mermel LA
    (2014) Changing epidemiology of infections due to extended spectrum beta-lactamase producing bacteria. Antimicrob Resist Infect Control 3:9.
    OpenUrl
  23. ↵
    1. Leistner R,
    2. Meyer E,
    3. Gastmeier P,
    4. Pfeifer Y,
    5. Eller C,
    6. Dem P,
    7. et al.
    (2013) Risk factors associated with the community-acquired colonization of extended-spectrum beta-lactamase (ESBL) positive Escherichia Coli an exploratory case-control study. PLoS One 8:e74323.
    OpenUrlCrossRefPubMed
  24. ↵
    1. El-Kersh TA,
    2. Marie TA,
    3. Al-Sheikh YA,
    4. Al-Kahtani YA
    (2015) Prevalence and risk factors of community-acquired urinary tract infections due to ESBL-producing Gram negative bacteria in an Armed Forces Hospital in Sothern Saudi Arabia. Global Advanced Research Journal of Medicine and Medical Sciences 4:321–330.
    OpenUrl
  25. ↵
    1. Al-Otaibi FE,
    2. Bukhari EE
    (2013) Clinical and laboratory profiles of urinary tract infections caused by extended-spectrum beta-lactamase-producing Escherichia coli in a tertiary care center in central Saudi Arabia. Saudi Med J 34:171–176.
    OpenUrlPubMed
  26. ↵
    1. Al Yousef SA,
    2. Younis S,
    3. Farrag E,
    4. Moussa HSh,
    5. Bayoumi FS,
    6. Ali AM
    (2016) Clinical and Laboratory Profile of Urinary Tract Infections Associated with Extended Spectrum β-Lactamase Producing Escherichia coli and Klebsiella pneumoniae. Ann Clin Lab Sci 46:393–400.
    OpenUrlAbstract/FREE Full Text
  27. ↵
    1. Rahim MA,
    2. Mitram P,
    3. Haque A,
    4. Zaman S,
    5. Samad T,
    6. Wasim MD,
    7. et al.
    (2018) Urinary Tract Infection due to Extended-Spectrum Beta-Lactamase Producing Organisms is a Risk Factor for Acute Kidney Injury among Patients with Type 2 Diabetes Mellitus. J Medicine 19:40–43.
    OpenUrl
  28. ↵
    1. Kaya O,
    2. Akcam FZ,
    3. Gonen I,
    4. Unal O,
    5. Ceylan T
    (2013) Risk factors for bacteremia due to extended-spectrum beta-lactamase-producing Escherichia coli in a Turkish hospital. J Infect Dev Ctries 7:507–512.
    OpenUrl
  29. ↵
    1. Blom A,
    2. Ahl J,
    3. Månsson F,
    4. Resman F,
    5. Tham J
    (2016) The prevalence of ESBL-producing Enterobacteriaceae in a nursing home setting compared with elderly living at home:a cross-sectional comparison. BMC Infect Dis 16:111.
    OpenUrl
  30. ↵
    1. Vijayakanthi N,
    2. Bahl D,
    3. Kaur N,
    4. Maria A,
    5. Dubey NK
    (2013) Frequency and characteristics of infections caused by extended-spectrum beta-lactamase-producing organisms in neonates:a prospective cohort study. Biomed Res Int 2013:756209.
    OpenUrl
  31. ↵
    1. Quan J,
    2. Zhao D,
    3. Liu L,
    4. Chen Y,
    5. Zhou J,
    6. Jiang Y,
    7. et al.
    (2017) High prevalence of ESBL-producing Escherichia coli and Klebsiella pneumoniae in community-onset bloodstream infections in China. J Antimicrob Chemother 72:273–280.
    OpenUrlCrossRefPubMed
  32. ↵
    1. Khalid A,
    2. Javaid U,
    3. Fatima F,
    4. Afreenish H,
    5. Maria O,
    6. Rabia A
    (2013) The frequency and antimicrobial sensitivity pattern of extended spectrum -lactamase (ESBLs) producing gram negative bacilli isolated from urine in a tertiary care hospital of Pakistan. Afr J Microbiol Res 7:2040–2043.
    OpenUrl
  33. ↵
    1. Shakya P,
    2. Shrestha D,
    3. Maharjan E,
    4. Sharma VK,
    5. Paudyal R
    (2017) ESBL Production Among E. coli and Klebsiella spp. Causing Urinary Tract Infection:A Hospital Based Study. Open Microbiol J 11:23–30.
    OpenUrlCrossRef
  34. ↵
    1. Tham J
    (2012) Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae: Epidemiology, Risk Factors, and Duration of Carriage (Department of Clinical Sciences, Lund University, Sweden).
  35. ↵
    1. Sid Ahmed MA,
    2. Bansal D,
    3. Acharya A,
    4. Elmi AA,
    5. Hamid JM,
    6. Sid Ahmed AM,
    7. et al.
    (2016) Antimicrobial susceptibility and molecular epidemiology of extended-spectrum betalactamase-producing Enterobacteriaceae from intensive care units at Hamad Medical Corporation, Qatar. Antimicrob Resist Infect Control 5:4.
    OpenUrl
  36. ↵
    1. Evans BA,
    2. Amyesb SG
    (2014) OXA-Lactamases. Clin Microbiol Rev 27:241–263.
    OpenUrlAbstract/FREE Full Text
  37. ↵
    1. Sharma M,
    2. Pathak S,
    3. Srivastava P
    (2013) Prevalence and antibiogram of Extended Spectrum β-Lactamase (ESBL) producing Gram negative bacilli and further molecular characterization of ESBL producing Escherichia coli and Klebsiella spp. J Clin Diagn Res 7:2173–2177.
    OpenUrl
  38. ↵
    1. Dehshiri M,
    2. Khoramrooz SS,
    3. Zoladl M,
    4. Khosravani SA,
    5. Parhizgari N,
    6. Motazedian MH,
    7. et al.
    (2018) The frequency of Klebsiella pneumonia encoding genes for CTX-M, TEM-1 and SHV-1 extended-spectrum beta lactamases enzymes isolated from urinary tract infection. Ann Clin Microbiol Antimicrob 17:4.
    OpenUrl
  39. ↵
    1. Abdallah QM
    (2014) Medicines use among general public in Taif, KSA. Arch Pharma Pract 5:125–131.
    OpenUrl
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Saudi Medical Journal: 39 (12)
Saudi Medical Journal
Vol. 39, Issue 12
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Risk factors and molecular features of extended-spectrum beta-lactamase producing bacteria at southwest of Saudi Arabia
Saleh M. Al-Garni, Mabrouk M. Ghonaim, Mohamed Morsi M. Ahmed, Ali S. Al-Ghamdi, Farooq A. Ganai
Saudi Medical Journal Dec 2018, 39 (12) 1186-1194; DOI: 10.15537/smj.2018.12.23273

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Risk factors and molecular features of extended-spectrum beta-lactamase producing bacteria at southwest of Saudi Arabia
Saleh M. Al-Garni, Mabrouk M. Ghonaim, Mohamed Morsi M. Ahmed, Ali S. Al-Ghamdi, Farooq A. Ganai
Saudi Medical Journal Dec 2018, 39 (12) 1186-1194; DOI: 10.15537/smj.2018.12.23273
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