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Research ArticleOriginal Article
Open Access

The role of hydroxyurea in decreasing the occurrence of vasso-occulusive crisis in pediatric patients with sickle cell disease at King Saud Medical City in Riyadh, Saudi Arabia

Fauzia R. Azmet, Fawaz Al-Kasim, Walid M. Alashram and Khawar Siddique
Saudi Medical Journal January 2020, 41 (1) 46-52; DOI: https://doi.org/10.15537/smj.2020.1.24698
Fauzia R. Azmet
From the Department of Pediatric Hematology and Oncology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia
MRCPCH, SFPHO
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  • For correspondence: [email protected]
Fawaz Al-Kasim
From the Department of Pediatric Hematology and Oncology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia
FRCP, CFPHO
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Walid M. Alashram
From the Department of Pediatric Hematology and Oncology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia
MBBS, DCH
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Khawar Siddique
From the Department of Pediatric Hematology and Oncology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia
MSc, MBA
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Article Information

vol. 41 no. 1 46-52
DOI 
https://doi.org/10.15537/smj.2020.1.24698
PubMed 
31915794

Published By 
Saudi Medical Journal
Online ISSN 
1658-3175
History 
  • Received July 15, 2019
  • Accepted October 29, 2019
  • Published online January 1, 2020.

Copyright & Usage 
Copyright: © Saudi Medical Journal This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Information

  1. Fauzia R. Azmet, MRCPCH, SFPHO⇑,
  2. Fawaz Al-Kasim, FRCP, CFPHO,
  3. Walid M. Alashram, MBBS, DCH and
  4. Khawar Siddique, MSc, MBA
  1. From the Department of Pediatric Hematology and Oncology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia
  1. Address correspondence and reprint request to: Dr. Fauzia Azmet, Department of Pediatric Hematology and Oncology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail: fauziarehmanazmet{at}yahoo.com ORCID ID: orcid.org/0000-0002-7643-8653
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Cited By...

  • 7 Citations
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  • The impact of Hydroxyurea on the rates of Vaso–occlusive crises in patients with sickle cell disease in Saudi Arabia: a single–center study
    Sahar Abdullah Alkhalifah, Miteb Alanazi, Majed Ali Almasaoud, Hazim Saeed Al-Malki, Faisal Mohammed Al-Murdhi, Mohammed Saad Al-hazzaa, Suliaman Musaed Al-Mufarrij, Mohammed Ali Albabtain, Abdulrahman Abdullah Alshiakh, Yazed AlRuthia
    BMC Emergency Medicine 2022 22 1
  • Utilization of Hydroxyurea Among Patients Diagnosed with Sickle Cell Disease in Jazan, Saudi Arabia
    Gassem A Gohal, Ibrahim M Gosadi, Basheer Ahmed Cittana Iqbal, Yahya H Ghazwani, Amal M Daghriri, Ahmad A Shugairi, Khaled A Daghriri, Atyaf J Zurayyir, Abdulrhman A Nemri, Monera A Abdulhaq
    Patient Preference and Adherence 2022 Volume 16
  • Frequency of Painful Crisis and Other Associated Complications of Sickle Cell Anemia Among Children
    Jana S Sendy, Mohammed S Alsadun, Sarah S Alamer, Shujon M Alazzam, Mansour M Alqurashi, Adel H Almudaibigh
    Cureus 2023
  • Utilization and Perceptions of Hydroxyurea Therapy Among Adult Patients With Sickle Cell Disease in Al Ahsa, Saudi Arabia: A Cross-Sectional Study
    Intithar H Alherz, Zainab J Al-Nass, Mohammed A Alkadi
    Cureus 2024
  • Clinical Insights into Sickle Cell Disease: A Comprehensive Multicenter Retrospective Analysis of Clinical Characteristics and Outcomes Across Different Age Groups
    Daniyah A. Almarghalani, Renad A. Alotaibi, Teef T. Alzlami, Ozouf F. Alhumaidi, Najla M. Alharthi, Fatimah M. Alboqami, Khulood A. Almehmadi, Samar F. Miski, Ali Alshahrani, Faisal F. Alamri, Khadeejah Alsolami, Suhaib Mamduh Doman, Maha T. Alhamdi, Areej Zubaid, Wasan S. Aloufi
    Journal of Clinical Medicine 2024 13 23
  • Prevalence, Risk Factors, and Complications of Sickle Cell Disease in Saudi Arabia: A Systematic Review
    Nazim F Hamed, Yousef Dakheel Allah Alatawi, Danya Mohammed Zuhair AlKabbani
    Cureus 2024
  • The vaso-occlusive pain crisis in sickle cell patients: A focus on pathogenesis
    Fatemeh Javaherforoosh Zadeh, Azadeh Fateh, Hamed Saffari, Mohammadtaghi Khodadadi, Mohammadamin Eslami Samarin, Nasim Nikoubakht, Fatemeh Dadgar, Vahid Goodarzi
    Current Research in Translational Medicine 2025 73 3
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The role of hydroxyurea in decreasing the occurrence of vasso-occulusive crisis in pediatric patients with sickle cell disease at King Saud Medical City in Riyadh, Saudi Arabia
Fauzia R. Azmet, Fawaz Al-Kasim, Walid M. Alashram, Khawar Siddique
Saudi Medical Journal Jan 2020, 41 (1) 46-52; DOI: 10.15537/smj.2020.1.24698

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The role of hydroxyurea in decreasing the occurrence of vasso-occulusive crisis in pediatric patients with sickle cell disease at King Saud Medical City in Riyadh, Saudi Arabia
Fauzia R. Azmet, Fawaz Al-Kasim, Walid M. Alashram, Khawar Siddique
Saudi Medical Journal Jan 2020, 41 (1) 46-52; DOI: 10.15537/smj.2020.1.24698
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Keywords

  • sickle cell disease
  • hydroxyurea
  • pediatric
  • vaso-occlusive crisis

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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