Prevalence of COVID-19 antibodies among operating room and critical care staff at a tertiary teaching hospital: A cross-sectional study

Article Figures & Data

Table 1

- Baseline characteristics for the 319 participants.

Variable	n	(%)
Age in years [mean ± SD] (n=282)	37.3 ± 8.6	NA
Female (n=298)	162	(54)
Division (n=317)
Nursing	130	(40.8)
Anesthesia	71	(22.3)
Surgery	54	(16.9)
Critical care	31	(9.7)
Respiratory therapy	13	(4.1)
Others	20	(6.3)
Occupation	312	(41.7)
Nurse	133	(17.2)
Consultant	55	(12.5)
Registrar	40	(11.3)
Resident	36	(6.5)
Technician	21	(4.4)
Respiratory therapist	14	(6.3)
Others	20
Chronic disease (n=294)	104	(32.6)
Hypertension^†	34	(32.6)
Asthma^†	25	(24.0)
Diabetes^†	17	(16.3)
Others	25	(24.0)
Smoker	35	(10.9)
Blood group	300	(42.9)
O	137	(24.8)
A	79	(20.7)
B	66	(5.3)
AB	17	(0.3)
Don’t know	1
Number of participants with history of COVID-19 infection (n=311)	25	(7.8)
Recovered at home
Admitted to hospital but did not require	21	(84.6)
oxygen	4	(13.4)
Number of participants with symptoms of COVID-19 infection	226	(70.8)

↵^† Some participants had more than one chronic disease. COVID-19, coronavirus disease; RT-PCR: reverse transcription polymerase chain reaction, NA: not applicable

Table 2

- Risk factors for acquiring COVID-19 infection.

Variables	n	(%)
Contact with patient(s) diagnosed with COVID-19 (n=310)	246	(77.1)
Contact with household member diagnosed with COVID-19 (n=313)	38	(11.9)
Contact with non-household member diagnosed with COVID-19 (n=309)	125	(39.2)
Working in ICU (n=314)	119	(37.3)
Part of airway team (n=312)	101	(31.7)
Lack of PPE material (n=315)	118	(37.0)
Have intubated patient(s) diagnosed with COVID-19 (n=313)	98	(30.7)

Table 3

- Results related to COVID-19 testing.

Variables	n	(%)
Antibodies positive for COVID-19^*	39	(12.2)
Participants previously diagnosed with COVID-19 using RT-PCR	19	(48.7)
Participants had symptoms of COVID-19	34	(87.1)
Number of participants who suspected they had COVID-19 infection	103	(32.2)
Participants previously diagnosed with COVID-19 using RT-PCR	24	(23.3)
Participants had symptoms of COVID-19	95	(92.2)
Participants who were antibody-positive but had no prior diagnosis of COVID-19	10	(9.7)

↵* One sample was equivocal and was considered negative in the final analysis. RT-PCR: reverse transcription polymerase chain reaction

Table 4

- Association between risk factors for COVID-19 and developing COVID-19 infection or antibodies.

Variable (yes/no)	Blood Test		Odds ratio	95% CI	P-value
Variable (yes/no)	Negative	Positive	Odds ratio	95% CI	P-value
Contract with family member who has COVID-19	23/243	15/30	5.3	2.5-11.2	<0.001
Contract with non-family member who has COVID-19	103/163	21/22	1.4	0.7-2.6	0.314
History of chronic disease†	107/159	21/27	1.3	0.6-2.4	0.417
Presence of COVID-19 symptoms	181/85	39/6	3.1	1.2-7.5	0.011
Lack of PPE	177/95	24/21	1.5	0.8-3.0	0.160
Contact with patient(s) with COVID-19	203/63	38/7	1.6	0.7-4.0	0.227
Working In ICU	94/172	22/23	1.8	0.9-3.3	0.082
Part of Airway team	85/181	16/29	1.2	0.6-2.3	0.633
Participants have intubated patient with COVID-19	79/187	18/27	1.6	0.8-3.0	0.168
Participants had previously tested for COVID-19	119/147	35/10	4.3	2.1-9.0	<0.001
Participants have suspected they had COVID-19 infection	67/199	34/11	8.1	3.8-17.4	<0.001
Participants have a blood group O (vs. other type)	122/128	14/31	0.5	0.2-0.9	0.028
Participants are female (versus male)	108/141	24/21	1.5	0.8-2.8	0.216