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Research ArticleOriginal Articles
Open Access

Impacts and effects of COVID-19 infection in pregnancy

Amala Sunder, Bessy Varghese, Basma Darwish, Noor Shaikho and Mooza Rashid
Saudi Medical Journal January 2022, 43 (1) 67-74; DOI: https://doi.org/10.15537/smj.2022.43.1.20210694
Amala Sunder
From the Department of Obstetrics and Gynaecology, Bahrain Defence Force Hospital, Riffa, Bahrain.
MRCPI (OBG)
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  • For correspondence: [email protected]
Bessy Varghese
From the Department of Obstetrics and Gynaecology, Bahrain Defence Force Hospital, Riffa, Bahrain.
DGO
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Basma Darwish
From the Department of Obstetrics and Gynaecology, Bahrain Defence Force Hospital, Riffa, Bahrain.
MD
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Noor Shaikho
From the Department of Obstetrics and Gynaecology, Bahrain Defence Force Hospital, Riffa, Bahrain.
MD, BCh BAO
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Mooza Rashid
From the Department of Obstetrics and Gynaecology, Bahrain Defence Force Hospital, Riffa, Bahrain.
FRCOG
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    Figure 1

    - Scatter plot for correlation between gestational age (GA) at diagnosis and GA at delivery. Gestational age at diagnosis and GA at delivery were not found to be significantly associated. COVID-19: coronavirus disease -19

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    Figure 2

    - Complications by age. No significant association between the complications and maternal age of coronavirus disease -19 population. P-values of preeclampsia (p=0.610), miscarriage (p>0.05), stillborn (p>0.05), preterm (p=0.310), intrauterine growth restriction (p=0.510), neonatal intensive care unit (p=0.468)

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    Figure 3

    - Complications by body mass index (BMI). No significant association between the complications and maternal BMI of coronavirus disease -19 population. P-values of miscarriage (p>0.168), stillborn (p>0.05), preterm (p=0.555), intrauterine growth restriction (p=0.572), neonatal intensive care unit (p=0.872)

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    Figure 4

    - Outcome of pregnancy by gestational period at diagnosis.

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    Figure 5

    - Complications by gestational period at diagnosis. Significant association between miscarriage and trimester at diagnosis. P-values of preeclampsia (p>0.05), miscarriage (p<0.01), stillborn (p=0.292), preterm (p=0.300), intrauterine growth restriction (p=0.877), neonatal intensive care unit (p=0.703)

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    Table 1

    - Comparison of complications in COVID-19 positive and negative groups.

    ParametersCOVID-19 positive (n=74)COVID-19 negative (N=2870)P-valueTest
    n (%)
    PET3 (4.5)83 (3.1)0.476Fishers exact
    FGR10 (15.2)56 (2.1)<0.001Chi-square
    APH0 (0)17 (0.6)1.000Fishers exact
    Pre-term15 (22.7)363 (13.4)0.053Chi-square
    Miscarriage8 (10.8)168 (5.9)0.076Chi-square
    Preterm premature rupture of membranes2 (3.03)19 (0.7)0.096Fishers exact
    Stillborn1 (1.5)20 (0.7)0.415Fishers exact
    PPH (EBL)1 (1.5)24 (0.9)0.472Fishers exact
    NICU Admission8 (12.1)443 (16.4)0.275Chi-square
    • COVID-19: coronavirus disease -19, PET: pre-eclampsia, FGR: fetal growth restriction, APH: antepartum haemorrhage, PPH: postpartum haemorrhage, NICU: neonatal intensive care unit

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Saudi Medical Journal: 43 (1)
Saudi Medical Journal
Vol. 43, Issue 1
1 Jan 2022
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Impacts and effects of COVID-19 infection in pregnancy
Amala Sunder, Bessy Varghese, Basma Darwish, Noor Shaikho, Mooza Rashid
Saudi Medical Journal Jan 2022, 43 (1) 67-74; DOI: 10.15537/smj.2022.43.1.20210694

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Impacts and effects of COVID-19 infection in pregnancy
Amala Sunder, Bessy Varghese, Basma Darwish, Noor Shaikho, Mooza Rashid
Saudi Medical Journal Jan 2022, 43 (1) 67-74; DOI: 10.15537/smj.2022.43.1.20210694
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Keywords

  • fetal growth restriction
  • miscarriage
  • stillborn
  • gestational age
  • mortality

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