Research ArticleOriginal Article
Open Access

Post-amputation pain among lower limb amputees in a tertiary care hospital in Jeddah, Saudi Arabia

A retrospective study

Dareen A. AlMehman, Abrar S. Faden, Badr M. Aldahlawi, Mohammed S. Bafail, Maram T. Alkhatieb and Abdullah M. Kaki
Saudi Medical Journal February 2022, 43 (2) 187-196; DOI: https://doi.org/10.15537/smj.2022.43.2.20210609

References

  1. 1.↵
    2. Hsu E ,
    3. Cohen SP.
    Postamputation pain: epidemiology, mechanisms, and treatment. J Pain Res 2013; 6: 121–136.
    OpenUrlCrossRefPubMed
  2. 2.↵
    2. Grzebień A ,
    3. Chabowski M ,
    4. Malinowski M ,
    5. Uchmanowicz I ,
    6. Milan M ,
    7. Janczak D.
    Analysis of selected factors determining quality of life in patients after lower limb amputation- a review article. Pol Przegl Chir 2017; 89: 57–61.
    OpenUrl
  3. 3.↵
    2. Stern JR ,
    3. Wong CK ,
    4. Yerovinkina M ,
    5. Spindler SJ ,
    6. See AS ,
    7. Panjaki S , et al.
    A meta-analysis of long-term mortality and associated risk factors following lower extremity amputation. Ann Vasc Surg 2017; 42: 322–327.
    OpenUrlPubMed
  4. 4.↵
    2. Benzon H ,
    3. Raja SN ,
    4. Fishman S ,
    5. Liu S ,
    6. Cohen SP.
    Essentials of Pain Medicine 4th edition, In: Postamputation Pain. ELSEVIER; 2018. p 249.
  5. 5.↵
    2. Dillingham TR ,
    3. Pezzin LE ,
    4. MacKenzie EJ.
    Limb amputation and limb deficiency: epidemiology and recent trends in the United States. South Med J 2002; 95: 875–883.
    OpenUrlPubMedWeb of Science
  6. 6.↵
    2. Alotaibi A ,
    3. Perry L ,
    4. Gholizadeh L ,
    5. Al-Ganmi A.
    Incidence and prevalence rates of diabetes mellitus in Saudi Arabia: an overview. J Epidemiol Glob Health 2017; 7: 211–218.
    OpenUrl
  7. 7.↵
    2. Ephraim PL ,
    3. Wegener ST ,
    4. MacKenzie EJ ,
    5. Dillingham TR ,
    6. Pezzin LE.
    Phantom pain, residual limb pain, and back pain in amputees: results of a national survey. Arch Phys Med Rehabil 2005; 86: 1910–1919.
    OpenUrlCrossRefPubMedWeb of Science
  8. 8.↵
    2. Wartan SW ,
    3. Hamann W ,
    4. Wedley JR ,
    5. McColl I.
    Phantom pain and sensation among British veteran amputees. Br J Anaesth 1997; 78: 652–659.
    OpenUrlCrossRefPubMedWeb of Science
  9. 9.↵
    2. Smith DG ,
    3. Ehde DM ,
    4. Legro MW ,
    5. Reiber GE ,
    6. del Aguila M ,
    7. Boone DA.
    Phantom limb, residual limb, and back pain after lower extremity amputations. Clin Orthop Relat Res 1999: 29–38.
  10. 10.
    2. Ehde DM ,
    3. Czerniecki JM ,
    4. Smith DG ,
    5. Campbell KM ,
    6. Edwards WT ,
    7. Jensen MP , et al.
    Chronic phantom sensations, phantom pain, residual limb pain, and other regional pain after lower limb amputation. Arch Phys Med Rehabil 2000; 81: 1039–1044.
    OpenUrlCrossRefPubMedWeb of Science
  11. 11.↵
    2. Gallagher P ,
    3. Allen D ,
    4. Maclachlan M.
    Phantom limb pain and residual limb pain following lower limb amputation: a descriptive analysis. Disabil Rehabil 2001; 23: 522–530.
    OpenUrlCrossRefPubMedWeb of Science
  12. 12.↵
    2. Husum H ,
    3. Resell K ,
    4. Vorren G ,
    5. Heng YV ,
    6. Murad M ,
    7. Gilbert M , et al.
    Chronic pain in land mine accident survivors in Cambodia and Kurdistan. Soc Sci Med 2002; 55: 1813–1816.
    OpenUrlCrossRefPubMedWeb of Science
  13. 13.
    2. Ong BY ,
    3. Arneja A ,
    4. Ong EW.
    E ects of anesthesia on pain after lower-limb amputation. J Clin Anesth 2006; 18: 600–604.
    OpenUrlCrossRefPubMedWeb of Science
  14. 14.↵
    2. Hanley MA ,
    3. Jensen MP ,
    4. Smith DG ,
    5. Ehde DM ,
    6. Edwards WT ,
    7. Robinson LR.
    Preamputation pain and acute pain predict chronic pain after lower extremity amputation. J Pain 2007; 8: 102–109.
    OpenUrlCrossRefPubMedWeb of Science
  15. 15.
    2. Richardson C ,
    3. Glenn S ,
    4. Nurmikko T ,
    5. Horgan M.
    Incidence of phantom phenomena including phantom limb pain 6 months after major lower limb amputation in patients with peripheral vascular disease. Clin J Pain 2006; 22: 353–358.
    OpenUrlCrossRefPubMedWeb of Science
  16. 16.↵
    2. Probstner D ,
    3. uler LC ,
    4. Ishikawa NM ,
    5. Alvarenga RM
    . Phantom limb phenomena in cancer amputees. Pain Pract 2010; 10: 249–256.
    OpenUrlPubMed
  17. 17.↵
    2. Subedi B ,
    3. Grossberg GT.
    Phantom limb pain: mechanisms and treatment approaches. Pain Res Treat 2011; 2011: 864605.
    OpenUrlPubMed
  18. 18.↵
    2. Kooijman CM ,
    3. Dijkstra PU ,
    4. Geertzen JHB ,
    5. Elzinga A ,
    6. van der Schans CP.
    Phantom pain and phantom sensations in upper limb amputees: an epidemiological study. Pain 2000; 87: 33–41.
    OpenUrlCrossRefPubMedWeb of Science
  19. 19.↵
    2. Bouhassira D ,
    3. Attal N ,
    4. Alchaar H ,
    5. Boureau F ,
    6. Brochet B ,
    7. Bruxelle J , et al.
    Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). Pain 2005; 114: 29–36.
    OpenUrlCrossRefPubMedWeb of Science
  20. 20.↵
    2. Al-Wahbi AM.
    Impact of a diabetic foot care education program on lower limb amputation rate. Vasc Health Risk Manag 2010; 6: 923–934.
    OpenUrlPubMed
  21. 21.↵
    2. Krans-Schreuder HK ,
    3. Bodde MI ,
    4. Schrier E ,
    5. Dijkstra PU ,
    6. van den Dungen JA ,
    7. den Dunnen WF , et al.
    Amputation for long-standing, therapy-resistant type-I complex regional pain syndrome. J Bone Joint Surg Am 2012; 94: 2263–2268.
    OpenUrlAbstract/FREE Full Text
  22. 22.↵
    2. Davie-Smith F ,
    3. Coulter E ,
    4. Kennon B ,
    5. Wyke S ,
    6. Paul L.
    Factors influencing quality of life following lower limb amputation for peripheral arterial occlusive disease: a systematic review of the literature. Prosthet Orthot Int 2017; 41: 537–547.
    OpenUrl
  23. 23.↵
    2. Sin EI ,
    3. Thong SY ,
    4. Poon KH.
    Incidence of phantom limb phenomena after lower limb amputations in a Singapore tertiary hospital. Singapore Med J 2013; 54: 75–81.
    OpenUrlPubMedWeb of Science
  24. 24.↵
    2. Reiber GE.
    The epidemiology of diabetic foot problems. Diabet Med 1996; 13: S6–S11.
    OpenUrlPubMedWeb of Science
  25. 25.
    2. Qari FA ,
    3. Akbar D.
    Diabetic foot: presentation and treatment. Saudi Med J 2000; 21: 443–446.
    OpenUrlAbstract/FREE Full Text
  26. 26.↵
    2. Liu M ,
    3. Zhang W ,
    4. Yan Z ,
    5. Yuan X.
    Smoking increases the risk of diabetic foot amputation: a meta-analysis. Exp Ther Med 2018; 15: 1680–1685.
    OpenUrl
  27. 27.↵
    2. Al-Nozha MM ,
    3. Al-Maatouq MA ,
    4. Al-Mazrou YY ,
    5. Al-Harthi SS ,
    6. Arafah MR ,
    7. Khalil MZ , et al.
    Diabetes mellitus in Saudi Arabia. Saudi Med J 2004; 25: 1603–1610.
    OpenUrlAbstract/FREE Full Text
  28. 28.↵
    2. Finch DR ,
    3. Macdougal M ,
    4. Tibbs DJ ,
    5. Morris PJ.
    Amputation for vascular disease: the experience of a peripheral vascular unit. Br J Surg 1980; 67: 233–237.
    OpenUrlCrossRefPubMedWeb of Science
  29. 29.↵
    2. Hussain MA ,
    3. Al-Omran M ,
    4. Salata K ,
    5. Sivaswamy A ,
    6. Forbes TL ,
    7. Sattar N , et al.
    Population-based secular trends in lower- extremity amputation for diabetes and peripheral artery disease. CMAJ 2019; 191: E955–E961.
    OpenUrlAbstract/FREE Full Text
  30. 30.↵
    2. Nikolajsen L ,
    3. Jensen TS.
    Phantom limb pain. Br J Anaesth 2001; 87: 107–116.
    OpenUrlCrossRefPubMedWeb of Science
  31. 31.
    2. Flor H ,
    3. Nikolajsen L ,
    4. Staehelin Jensen T.
    Phantom limb pain: a case of maladaptive CNS plasticity? Nat Rev Neurosci 2006; 7: 873–881.
    OpenUrlCrossRefPubMedWeb of Science
  32. 32.
    2. Nikolajsen L ,
    3. Ilkjaer S ,
    4. Krøner K ,
    5. Christensen JH ,
    6. Jensen TS.
    Thee in uence of preamputation pain on postamputation stump and phantom pain. Pain 1997; 72: 393–405.
    OpenUrlCrossRefPubMedWeb of Science
  33. 33.↵
    2. Perkins FM ,
    3. Kehlet H.
    Chronic pain as an outcome of surgery. A review of predictive factors. Anesthesiology 2000; 93: 1123–1133.
    OpenUrlCrossRefPubMedWeb of Science
  34. 34.↵
    2. Yin Y ,
    3. Zhang L ,
    4. Xiao H ,
    5. Wen CB ,
    6. Dai YE ,
    7. Yang G , et al.
    e pre-amputation pain and the postoperative dea erentation are the risk factors of phantom limb pain: a clinical survey in a sample of Chinese population. BMC Anesthesiol 2017; 17: 69.
    OpenUrl
  35. 35.
    2. Dijkstra PU ,
    3. Geertzen JH ,
    4. Stewart R ,
    5. van der Schans CP.
    Phantom pain and risk factors: a multivariate analysis. J Pain Symptom Manage 2002; 24: 578–585.
    OpenUrlCrossRefPubMedWeb of Science
  36. 36.
    2. Weiser TG ,
    3. Regenbogen SE ,
    4. ompson KD ,
    5. Haynes AB ,
    6. Lipsitz SR ,
    7. Berry WR , et al.
    An estimation of the global volume of surgery: a modelling strategy based on available data. Lancet 2008; 372: 139–144.
    OpenUrlCrossRefPubMedWeb of Science
  37. 37.
    2. Manchikanti L ,
    3. Singh V.
    Managing phantom pain. Pain Physician 2004; 7: 365–375.
    OpenUrlPubMed
  38. 38.↵
    2. Kelle B ,
    3. Kozanoğlu E ,
    4. Biçer ÖS ,
    5. Tan İ.
    Association between phantom limb complex and the level of amputation in lower limb amputee. Acta Orthop Traumatol Turc 2017; 51: 142–145.
    OpenUrl
  39. 39.↵
    2. Stone PA ,
    3. Flaherty SK ,
    4. Aburahma AF ,
    5. Hass SM ,
    6. Jackson JM ,
    7. Hayes JD , et al.
    Factors a ecting perioperative mortality and wound-related complications following major lower extremity amputations. Ann Vasc Surg 2006; 20: 209–216.
    OpenUrlCrossRefPubMedWeb of Science
  40. 40.↵
    2. Woolf CJ.
    Pain: moving from symptom control toward mechanism-specific pharmacologic management. Ann Intern Med 2004; 140: 441–451.
    OpenUrlCrossRefPubMedWeb of Science
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