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Brief CommunicationBrief Communication
Open Access

False-positive Xpert® Xpress SARS-CoV-2 assay in an emergency room and trauma center

A retrospective chart review study

Hyerim Kim, Soeun Jeon, Sun Hack Lee, Hyun-Su Ri, Hyeon-Jeong Lee, Jeong-Min Hong and Sung In Paek
Saudi Medical Journal August 2022, 43 (8) 965-970; DOI: https://doi.org/10.15537/smj.2022.43.8.20220317
Hyerim Kim
From the Department of Laboratory Medicine (Kim); from Biomedical Research Institute (Kim, Jeon, S. H. Lee, H-J. Lee, Hong); from the Department of Anesthesia and Pain Medicine (Jeon, H-J. Lee, Hong, Paek); from the Department of Internal Medicine (S. H. Lee), Division of Cardiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, and from the Department of Anesthesia and Pain Medicine (Ri), Kyungpook National University, School of Medicine, Daegu, Korea.
MD, PhD
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Soeun Jeon
From the Department of Laboratory Medicine (Kim); from Biomedical Research Institute (Kim, Jeon, S. H. Lee, H-J. Lee, Hong); from the Department of Anesthesia and Pain Medicine (Jeon, H-J. Lee, Hong, Paek); from the Department of Internal Medicine (S. H. Lee), Division of Cardiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, and from the Department of Anesthesia and Pain Medicine (Ri), Kyungpook National University, School of Medicine, Daegu, Korea.
MD, PhD
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  • For correspondence: [email protected]
Sun Hack Lee
From the Department of Laboratory Medicine (Kim); from Biomedical Research Institute (Kim, Jeon, S. H. Lee, H-J. Lee, Hong); from the Department of Anesthesia and Pain Medicine (Jeon, H-J. Lee, Hong, Paek); from the Department of Internal Medicine (S. H. Lee), Division of Cardiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, and from the Department of Anesthesia and Pain Medicine (Ri), Kyungpook National University, School of Medicine, Daegu, Korea.
MD
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Hyun-Su Ri
From the Department of Laboratory Medicine (Kim); from Biomedical Research Institute (Kim, Jeon, S. H. Lee, H-J. Lee, Hong); from the Department of Anesthesia and Pain Medicine (Jeon, H-J. Lee, Hong, Paek); from the Department of Internal Medicine (S. H. Lee), Division of Cardiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, and from the Department of Anesthesia and Pain Medicine (Ri), Kyungpook National University, School of Medicine, Daegu, Korea.
MD, PhD
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Hyeon-Jeong Lee
From the Department of Laboratory Medicine (Kim); from Biomedical Research Institute (Kim, Jeon, S. H. Lee, H-J. Lee, Hong); from the Department of Anesthesia and Pain Medicine (Jeon, H-J. Lee, Hong, Paek); from the Department of Internal Medicine (S. H. Lee), Division of Cardiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, and from the Department of Anesthesia and Pain Medicine (Ri), Kyungpook National University, School of Medicine, Daegu, Korea.
MD, PhD
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Jeong-Min Hong
From the Department of Laboratory Medicine (Kim); from Biomedical Research Institute (Kim, Jeon, S. H. Lee, H-J. Lee, Hong); from the Department of Anesthesia and Pain Medicine (Jeon, H-J. Lee, Hong, Paek); from the Department of Internal Medicine (S. H. Lee), Division of Cardiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, and from the Department of Anesthesia and Pain Medicine (Ri), Kyungpook National University, School of Medicine, Daegu, Korea.
MD, PhD
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Sung In Paek
From the Department of Laboratory Medicine (Kim); from Biomedical Research Institute (Kim, Jeon, S. H. Lee, H-J. Lee, Hong); from the Department of Anesthesia and Pain Medicine (Jeon, H-J. Lee, Hong, Paek); from the Department of Internal Medicine (S. H. Lee), Division of Cardiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, and from the Department of Anesthesia and Pain Medicine (Ri), Kyungpook National University, School of Medicine, Daegu, Korea.
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References

  1. 1.↵
    1. Dong X,
    2. Liu L,
    3. Tu Y,
    4. Zhang J,
    5. Miao G,
    6. Zhang L, et al.
    Rapid PCR powered by microfluidics: a quick review under the background of COVID-19 pandemic. Trends Analyt Chem 2021; 143: 116377.
    OpenUrl
  2. 2.↵
    1. Das R,
    2. Joshi S,
    3. Pednekar S,
    4. Karyakarte R
    . Comparison of Xpert Xpress SARS-CoV-2 assay and RT-PCR test in diagnosis of COVID-19. IOSR J Dent Med Sci 2021; 20: 12–17.
    OpenUrl
  3. 3.↵
    1. Mouliou DS,
    2. Gourgoulianis KI
    . False-positive and false-negative COVID-19 cases: respiratory prevention and management strategies, vaccination, and further perspectives. Expert Rev Respir Med 2021; 15: 993–1002.
    OpenUrlPubMed
  4. 4.↵
    1. Healy B,
    2. Khan A,
    3. Metezai H,
    4. Blyth I,
    5. Asad H
    . The impact of false positive COVID-19 results in an area of low prevalence. Clin Med (Lond) 2021; 21: e54–e56.
    OpenUrl
  5. 5.↵
    1. Kim TY,
    2. Kim JY,
    3. Shim HJ,
    4. Yun SA,
    5. Jang JH,
    6. Huh HJ, et al.
    Performance evaluation of the PowerChek SARS-CoV-2, influenza A & B multiplex real-time PCR kit in comparison with the BioFire respiratory panel. Ann Lab Med 2022; 42: 473–477.
    OpenUrl
  6. 6.↵
    1. May L,
    2. Tran N,
    3. Ledeboer NA
    . Point-of-care COVID-19 testing in the emergency department: current status and future prospects. Expert Rev Mol Diagn 2021; 21: 1333–1340.
    OpenUrl
  7. 7.↵
    Cepheid. Xpert® Xpress SARS-CoV-2 instructions for use. [Updated 2021; 2022 Apr 4]. Available from: https://www.fda.gov/media/136314/download
  8. 8.↵
    1. Dinnes J,
    2. Deeks JJ,
    3. Adriano A,
    4. Berhane S,
    5. Davenport C,
    6. Dittrich S, et al.
    Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection. Cochrane Database Syst Rev 2020; 8: CD013705.
  9. 9.↵
    Korean Centers for Disease Control and Prevention. Past updates on the COVID-19 (February 25, 2022). [Updated 2022; Cited 2022 Apr 4]. Available from: http://ncov.mohw.go.kr/tcmBoardView.do?brdId=3&brdGubun=31&dataGubun=&ncvContSeq=6420&contSeq=6420&board_id=312&gubun=ALL
  10. 10.↵
    1. Lee HJ,
    2. Park OK,
    3. Park JS,
    4. Park DB,
    5. Seo MG,
    6. Kim H, et al.
    Analysis of testing results on temporary testing stations for COVID-19 in the Seoul Metropolitan Area, 2020-2021. Public Health Weekly Rep 2021; 14: 3610–3613.
    OpenUrl
  11. 11.↵
    Korean Centers for Disease Control and Prevention. Findings from investigation and analysis of re-positive cases. [Updated 2020; 2022 Apr 4]. Available from: https://www.mofa.go.kr/eng/brd/m_22743/view.do?seq=3&srchFr=&srchTo=&srchWord=&srchTp=&multi_itm_seq=0&itm_seq_1=0&itm_seq_2=0&company_cd=&company_nm=&page=1&titleNm=
  12. 12.↵
    1. Xing Y,
    2. Mo P,
    3. Xiao Y,
    4. Zhao O,
    5. Zhang Y,
    6. Wang F
    . Post-discharge surveillance and positive virus detection in 2 medical staff recovered from coronavirus disease 2019 (COVID-19), China, January to February 2020. Euro Surveill 2020; 25: 2000191.
    OpenUrl
  13. 13.↵
    1. Kang YJ
    . South Korea’s COVID-19 infection status: from the perspective of re-positive test results after viral clearance evidenced by negative test results. Disaster Med Public Health Prep 2020; 14: 762–764.
    OpenUrl
  14. 14.↵
    Korean Centers for Disease Control and Prevention. Korean government’s COVID-19 response guideline (12th edition). [Updated 2022; 2022 Apr 4]. Available from: http://ncov.mohw.go.kr/shBoardView.do?brdId=2&brdGubun=23&ncvContSeq=6413
  15. 15.↵
    1. Kahn M,
    2. Schuierer L,
    3. Bartenschlager C,
    4. Zellmer S,
    5. Frey R,
    6. Freitag M, et al.
    Performance of antigen testing for diagnosis of COVID-19: a direct comparison of a lateral flow device to nucleic acid amplification based tests. BMC Infect Dis 2021; 21: 798.
    OpenUrl
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Saudi Medical Journal: 43 (8)
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False-positive Xpert® Xpress SARS-CoV-2 assay in an emergency room and trauma center
Hyerim Kim, Soeun Jeon, Sun Hack Lee, Hyun-Su Ri, Hyeon-Jeong Lee, Jeong-Min Hong, Sung In Paek
Saudi Medical Journal Aug 2022, 43 (8) 965-970; DOI: 10.15537/smj.2022.43.8.20220317

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False-positive Xpert® Xpress SARS-CoV-2 assay in an emergency room and trauma center
Hyerim Kim, Soeun Jeon, Sun Hack Lee, Hyun-Su Ri, Hyeon-Jeong Lee, Jeong-Min Hong, Sung In Paek
Saudi Medical Journal Aug 2022, 43 (8) 965-970; DOI: 10.15537/smj.2022.43.8.20220317
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Keywords

  • COVID-19
  • SARS-CoV-2
  • COVID-19 nucleic acid testing
  • polymerase chain reaction
  • false positive reactions

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